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(E)-cinnamate compounds and synthetic methods thereof, and medicines containing compounds and application thereof

A technology of cinnamate esters and compounds, which is applied in the field of plant antibacterial drugs, can solve the problems that have not been seen-the research report of cinnamate ester compounds against plant pathogenic bacteria

Inactive Publication Date: 2017-04-26
NORTHWEST A & F UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, so far, no information on ( E )-Cinnamate Compounds Anti-Plant Pathogenic Bacteria Research Report

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  • (E)-cinnamate compounds and synthetic methods thereof, and medicines containing compounds and application thereof
  • (E)-cinnamate compounds and synthetic methods thereof, and medicines containing compounds and application thereof
  • (E)-cinnamate compounds and synthetic methods thereof, and medicines containing compounds and application thereof

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Embodiment Construction

[0028] The present invention will be described in detail below in combination with specific embodiments.

[0029] The present invention is based on the research on the anti-phytopathogenic fungus activity of various cinnamic acid esters, and adopts the strategy of combining active structural units to design and synthesize a new class of ( E )-cinnamate compounds, and found that these compounds have significant inhibitory activity on various plant diseases, and have the potential to be used as active ingredients in the preparation of plant antibacterial agents.

[0030] The (E)-cinnamate compounds involved in the present invention have the following molecular structure characteristics:

[0031]

[0032] in:

[0033] R 1 is a saturated or unsaturated non-aromatic hydrocarbon group, phenyl, substituted phenyl, aromatic heterocyclic group, hydrocarbon group containing phenyl, substituted phenyl or aromatic heterocyclic group;

[0034] R 2 , R 3 , R 4 , R 5 , R 6 are the...

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Abstract

The invention relates to (E)-cinnamate compounds and synthetic methods thereof, and medicines containing the compounds and application thereof. According to the invention, on the basis of research on the activity of various cinnamates to resistance of plant pathogenic fungi, the novel (E)-cinnamate compounds are designed and synthesized by using a strategy of combination of active structure units; and it is found that the compounds have substantial inhibitory activity to a plurality of plant diseases and have the potential to application as active components to preparation of antibacterial agents for plants.

Description

technical field [0001] The invention relates to plant antibacterial drugs, in particular to a class of (E)-cinnamate compounds and their synthesis methods, as well as drugs and applications containing the compounds. Background technique [0002] Phytopathogenic bacteria have a very serious impact on the healthy growth and development of plants, the yield and quality of crop products. Therefore, the application of plant fungicides is of great significance in modern agriculture. However, long-term repeated use of the same fungicide has resulted in strong resistance of plant pathogens to many current plant fungicides. In addition, many countries have banned the use of some agricultural fungicides that have adverse effects on the environment, people or ecology. Therefore, it is of great significance to research and develop new plant fungicides with high efficiency, low toxicity and environmental protection. [0003] The research and development of new drugs led by natural act...

Claims

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Application Information

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IPC IPC(8): C07C69/732C07C69/736C07C69/73C07C69/618C07C67/14C07C67/39A01N37/38A01N37/10A01P3/00
CPCA01N37/10A01N37/38C07C69/618C07C69/73C07C69/732C07C69/736
Inventor 周乐周琨陈栋栋张冰玉周搏航
Owner NORTHWEST A & F UNIV
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