Same-kind costicartilage material for nasal part plastic filling and preparation method therefor
A costal cartilage and nasal technology, which is applied in the field of rhinoplasty to fill the same kind of costal cartilage material and its preparation, can solve the problems of complex production process, easy displacement and wear, and achieve the effect of preventing pain and movement
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[0039] refer to image 3 As shown, the present invention also proposes a preparation method for filling the same costal cartilage material for rhinoplasty, comprising the following steps:
[0040] A) Bone extraction, the costal cartilage is obtained under a sterile environment, wherein the costal cartilage is a region.
[0041] B) processing, the obtained costal cartilage is sequentially degreased, decalcified, deproteinized and sterilized;
[0042] C) Carve, carve the costal cartilage after the above treatment into the desired shape.
[0043] Concrete process in the step B of the present invention comprises:
[0044] (1) immerse the costal cartilage in the mixed liquid of chloroform and methanol for 6-24 hours; wherein: the volume ratio of chloroform and methanol in the mixed liquid of chloroform and methanol is 1:1;
[0045] (2) adding the costal cartilage treated in the above step (1) into the hydrochloric acid solution, and continuously stirring for 8-12 hours; the conc...
Embodiment 1
[0050] 1. Obtain autologous rib cartilage in a sterile environment; preferably remove the eleventh or twelfth rib, clean it with distilled water and soak it;
[0051] 2. Immerse the costal cartilage in a mixed liquid of chloroform and methanol for 24 hours to degrease; wherein: the volume ratio of chloroform and methanol in the mixed liquid of chloroform and methanol is 1:1, and clean it with distilled water after taking it out;
[0052] 3. Immerse the degreased costal cartilage in a hydrochloric acid solution with a concentration of 0.5mol / L, and keep stirring for 12 hours to decalcify it, and wash it with distilled water after taking it out;
[0053] 4. Immerse the decalcified costal cartilage in a mixed solution of TritonX-100 and ammonia water for 72 hours to deproteinize; wherein, the volume percentage of TritonX-100 in the mixed solution of TritonX-100 and ammonia water is 1.5%, The mass percentage of ammonia is 0.3%, and after taking it out, it is cleaned with distilled...
Embodiment 2
[0057] 1. Obtain non-autologous rib cartilage in a sterile environment; preferably remove the eleventh or twelfth rib, clean it with distilled water and soak it;
[0058] 2. Immerse the costal cartilage in a mixed liquid of chloroform and methanol for 24 hours to degrease; wherein: the volume ratio of chloroform and methanol in the mixed liquid of chloroform and methanol is 1:1, and clean it with distilled water after taking it out;
[0059] 3. Immerse the degreased costal cartilage in a hydrochloric acid solution with a concentration of 0.6mol / L, and keep stirring for 12 hours for decalcification, and wash it with distilled water after taking it out;
[0060] 4. Immerse the decalcified costal cartilage in a mixed solution of TritonX-100 and ammonia water for 72 hours to deproteinize; wherein, the volume percentage of TritonX-100 in the mixed solution of TritonX-100 and ammonia water is 0.5%, The mass percentage of ammonia is 0.3%, and after taking it out, it is cleaned with d...
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