Cooperative medicament level sodium alginate and alginate-originated oligosaccharide technological method

Abstract

The application discloses cooperative medicament level sodium alginate and alginate-originated oligosaccharide technological method, wherein the provided steps include taking dry sodium alginate and leaching, digesting, diluting, foaming, floating, and primary fine filtrating, and resulting in clear solution C, exploiting soda solution and regulating pH, adding activated charcoal in the clear solution C and tarnishing through absorption, then fine filtrating two stage through a closed frame filter and paper board filter, conducting weight metal absorption of the filtrating solution through ion exchange resin, and resulting in clear solution F, acidifying, dewatering, rinsing the clear solution F, partially degrading and decomposing by adding lyase, centrifugally separating undissolved acid block, solid neutralizing to result in medicament level sodium alginate, mist spray drying the filtration solution and resulting in alginate-originated oligosaccharide. The composite yield of the two types of products is high, the weight metal content of sodium alginate is low, the endotoxin is low, the weight metal content of alginate-originated oligosaccharide is low, the cooperative medicament level sodium alginate and alginate-originated oligosaccharide technological method satisfies applications in cosmetic industry.

Description

technical field [0001] The invention belongs to the technical field of seaweed chemical industry, and in particular relates to a process capable of co-producing pharmaceutical-grade alginate and alginate oligosaccharide. Background technique [0002] Alginate is a substance extracted and separated from brown algae, and it is a white or light yellow powder. Alginate is composed of mannuronic acid (M) and guluronic acid (G) in different proportions. The M / G ratio is generally determined by the raw materials. The ratio of M / G prepared from macroalgae is 0.842-1.66. The M / G ratio of alginate prepared from kelp is 2.15-2.35. The gel formed by the alginate product with a higher M / G ratio is softer, which is more in line with market demand, but a large number of literatures show that changing the ratio of M / G is often at the expense of raw material yield. In addition, some pharmaceutical grade alginate currently require low endotoxin, low heavy metals, and low viscosity. However...

AI Technical Summary

Problems solved by technology

However, algin itself has a strong ability to adsorb heavy metals. The end product of the existing algin production technology has a relatively high heavy metal content, which cannot meet the standards for the use of pharmaceutical grade algin.

Images