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Material used for autologous cortical bone synostosis silica gel particle for nasal plasty and preparation method of material

A technology of silica gel particles and cortical bone, applied in prostheses, nose implants, medical science, etc., can solve the problems of complex production process, easy displacement and wear, and achieve the effect of preventing pain and movement

Inactive Publication Date: 2017-02-22
大连裕辰科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The invention provides a material and a preparation method for filling autologous cortical bone combined with silica gel particles for nasal plastic surgery, so as to solve the problems in the prior art that the production process is relatively complicated and prone to displacement and wear.

Method used

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  • Material used for autologous cortical bone synostosis silica gel particle for nasal plasty and preparation method of material
  • Material used for autologous cortical bone synostosis silica gel particle for nasal plasty and preparation method of material
  • Material used for autologous cortical bone synostosis silica gel particle for nasal plasty and preparation method of material

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preparation example Construction

[0044] refer to image 3 As shown, the present invention also proposes a method for preparing a material for filling autologous cortical bone combined with silica gel particles for rhinoplasty, comprising the following steps:

[0045] A) matrix production, using silica gel particles to make the nasal bone matrix;

[0046] B) taking bone, and obtaining autologous cortical bone in a sterile environment;

[0047] C) processing, performing degreasing, decalcifying, deproteinizing and sterilizing the obtained autologous cortical bone in sequence;

[0048] D) culturing, assembling the treated autologous cortical bone in step C onto the nasal bone matrix, and culturing for 24 hours,

[0049] E) Carve, carve the nasal bone matrix into the required shape after the cultivation in step D).

[0050] Concrete processing in the step C of the present invention comprises:

[0051](1) immersing the autologous cortical bone in a mixed liquid of chloroform and methanol for 6-24 hours; wherei...

Embodiment 1

[0057] 1. The nasal bone matrix is ​​made of silica gel particles, and there are many hollow holes on the nasal bone matrix;

[0058] 2. Obtain autologous rib cartilage in a sterile environment; preferably take the eleventh or twelfth rib, clean it with distilled water and soak it;

[0059] 3. Immerse the autologous cortical bone in a mixed liquid of chloroform and methanol for 24 hours to degrease; wherein: the volume ratio of chloroform and methanol in the mixed liquid of chloroform and methanol is 1:1, and wash it with distilled water after taking it out;

[0060] 4. Immerse the degreased autologous cortical bone in a hydrochloric acid solution with a concentration of 0.5 mol / L, and keep stirring for 12 hours for decalcification, and wash it with distilled water after taking it out;

[0061] 5. Immerse the decalcified autologous cortical bone in a mixed solution of TritonX-100 and ammonia water for 72 hours to deproteinize; wherein, the volume percentage of TritonX-100 in t...

Embodiment 2

[0066] 1. The nasal bone matrix is ​​made of silica gel particles, and there are many hollow holes on the nasal bone matrix;

[0067] 2. Obtain autologous ear cartilage in a sterile environment; clean and soak in distilled water;

[0068] 3. Immerse the autologous cortical bone in a mixed liquid of chloroform and methanol for 24 hours to degrease; wherein: the volume ratio of chloroform and methanol in the mixed liquid of chloroform and methanol is 1:1, and wash it with distilled water after taking it out;

[0069] 4. Immerse the degreased autologous cortical bone in a hydrochloric acid solution with a concentration of 0.6 mol / L, and keep stirring for 12 hours for decalcification, and wash it with distilled water after taking it out;

[0070] 5. Immerse the decalcified autologous cortical bone in a mixed solution of TritonX-100 and ammonia water for 72 hours to deproteinize; wherein, the volume percentage of TritonX-100 in the mixed solution of TritonX-100 and ammonia water is...

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Abstract

The invention relates to a material used for an autologous cortical bone synostosis silica gel particle for nasal plasty and a preparation method of the material. The material structurally comprises a nasal bone base body made of the silica gel particle, the nasal bone base body comprises an apex nasi, a columella nasi and a nose ridge, the nose ridge is connected with the columella nasi through the apex nasi; the lower part of the nose ridge comprises two nose ridge sections arranged in a V shape in a crossing manner, a nasal bone of a human body is located between the two nose ridge sections to ensure that a prosthesis does not displace or abrade, the nasal bone base body is provided with a hollow body, and the hollow body is filled with an autologous cortical bone. The material and the preparation method have the beneficial effects that due to the design of the nose ridge section, the prosthesis is tightly in contact with the nose bone and does not displace or abrade; and a body fluid flows into a hole in the nose ridge to grow a human tissue, so that the stable fusion of the nose and the nose prosthesis is promoted, the nose prosthesis is prevented from moving, falling off or festering, and the pain of a patient is prevented after the operation. The method is suitable for treating the autologous or allogeneic bone synostosis silica gel particles.

Description

technical field [0001] The invention relates to the technical field of plastic surgery, in particular to a material for filling autologous cortical bone combined with silica gel particles for nasal plastic surgery and a preparation method thereof. Background technique [0002] Rhinoplasty (facelift) surgery is to change the height and shape of the nose by implanting appropriate materials so that it is in harmony with other parts of the face. It is the most common surgery in the field of plastic surgery. [0003] In medicine, there are many kinds of rhinoplasty materials, such as medical silicone rubber, autologous cartilage, allogeneic cartilage, animal tendon or ligament, expanded body (polytetrafluoroethylene), hyaluronic acid, etc. There are also many preparation methods for nasal bridge prosthesis. Among them, autologous cartilage is self-sourced, so it will not be rejected or sensitized, but it is difficult to shape during the production process, which increases the pai...

Claims

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Application Information

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IPC IPC(8): A61L27/02A61L27/36A61L27/56A61F2/18
CPCA61L27/025A61L27/3608A61L27/3683A61L27/56A61F2/186A61F2210/00A61L2430/40
Inventor 于浩
Owner 大连裕辰科技发展有限公司
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