Application of taxol in prevention and treatment of pericardial effusion of chickens

A technology of Ankara disease and paclitaxel, applied in the direction of application, medical preparations containing active ingredients, antiviral agents, etc., to achieve the effects of improving the body's immunity, high feed conversion rate and production performance

Inactive Publication Date: 2017-02-22
ANHUI HUAAO BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Ankara is a new chicken disease that mainly affects broiler chickens aged 3-6 weeks. Occasionally occurs in replacement hens and laying hens. The disease was first discovered near Ankara in Karachi, Pakistan. When the affected chickens are more than 3 weeks old Death begins and reaches a peak at 4-5 weeks of age. The peak duration is 4-8 days. The mortality rate decreases at 5-6 weeks of age. The disease course is 8-15 days, and the mortality rate reaches 20-80%. It can be transmitted vertically and horizontally. Easily associated with infectious bursa and infectious anemia, characterized by sudden fall to the ground without obvious aura, depression, feathers in bundles, yellow and thin feces, and empty legs. In the summer of 1988, the disease had passed Spread to the whole of Pakistan, resulting in the death of hundreds of millions of broiler chickens, and now this case is gradually appearing in our country. At present, peptide nucleic acid, amoxicillin, or doxycycline and other drugs are usually used in combination with seasoning. The disease has been controlled to a certain extent, but it has not been able to complete prevention
[0003] Paclitaxel is a tetracyclic diterpene compound. According to Ⅱ-Ⅲ clinical research, paclitaxel is mainly suitable for ovarian cancer and breast cancer, and also has certain effects on lung cancer, colorectal cancer, melanoma, head and neck cancer, lymphoma and brain tumor. Efficacy, by promoting tubulin polymerization, inhibiting depolymerization, maintaining tubulin stability, and inhibiting cell mitosis, there is currently no related technology for paclitaxel for adenovirus Ankara

Method used

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Effect test

Embodiment 1

[0014] The invention relates to the application of paclitaxel in the prevention and treatment of chicken Ankara disease, and is used as a feed additive for preventing and treating chicken Ankara disease.

[0015] Wherein, the chicken feed is a full-price feed for corresponding day-old chickens.

[0016] Wherein, the feed additive also includes evening primrose oil equivalent to 50% by weight of paclitaxel, and 40% tylosin.

[0017] Wherein, the paclitaxel is extracted from yew bark with a water content of 15-18%.

[0018] In actual use, the feed additive containing paclitaxel is prevented when the broiler chicken is 2-6 weeks old, and the content in the chicken feed at this stage is: 0.65-0.95kg / ton of chicken feed; when symptoms of illness appear, To treat it, the content in chicken feed is: 0.95-1.35kg / ton of chicken feed, and it can be used continuously for 5-7 days.

[0019] In the susceptible area, paclitaxel, evening primrose oil and tylosin were added to the feed, whi...

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Abstract

The invention belongs to the technical field of disease prevention of agricultural breeding, and particularly relates to application of taxol in prevention and treatment of pericardial effusion of chickens. The taxol is used for a feed additive for preventing and treating the pericardial effusion of the chickens. Compared with the prior art, the application of taxol in prevention and treatment of pericardial effusion of chickens has the advantages that new application of the taxol is provided, and the taxol is used for preventing and treating the pericardial effusion of the chickens, and plays an important role in large-scale breeding of broilers; and the taxol, evening primrose oil and tylosin are used in feedstuff in a matched manner, and the pericardial effusion of the chickens can be effectively prevented and treated in a growth stage of the chickens, meanwhile, immunity of the organism can further be improved, and high feed conversion ratio and high production performance can be kept.

Description

technical field [0001] The invention belongs to the technical field of agricultural breeding and disease prevention, and in particular relates to the application of paclitaxel in preventing and treating chicken Ankara disease. Background technique [0002] Ankara is a new chicken disease that mainly affects broiler chickens aged 3-6 weeks. Occasionally occurs in replacement hens and laying hens. The disease was first discovered near Ankara in Karachi, Pakistan. When the affected chickens are more than 3 weeks old Death begins and reaches a peak at 4-5 weeks of age. The peak duration is 4-8 days. The mortality rate decreases at 5-6 weeks of age. The disease course is 8-15 days, and the mortality rate reaches 20-80%. It can be transmitted vertically and horizontally. Easily associated with infectious bursa and infectious anemia, characterized by sudden fall to the ground without obvious aura, depression, feathers in bundles, yellow and thin feces, and empty legs. In the summer...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/337A61K36/185A61P31/20A61P37/04A23K50/75A23K20/121A23K20/158A23K20/195
CPCA61K31/337A61K31/7048A61K36/13A61K36/185A61K2300/00
Inventor 袁士雄王君王丽霞
Owner ANHUI HUAAO BIOTECH
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