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A traditional Chinese medicine composition for improving bone pain in tumor patients and its application in analgesia

A tumor patient and composition technology, which can be used in drug combinations, anti-tumor drugs, and medical preparations containing active ingredients, etc., can solve the addiction and tolerance of painkillers. To improve the quality of life and immune function, and to synergistically treat bone metastases

Active Publication Date: 2019-09-27
LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to overcome the problems of addiction and tolerance of the existing analgesic drugs and the limited efficacy of bisphosphonate drugs in the prior art as an analgesic drug for tumor bone metastasis, and the accompanying It has the problem of reducing the quality of life and immune function of patients and producing side effects of drug toxicity, and provides a traditional Chinese medicine composition for improving bone pain in tumor patients

Method used

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  • A traditional Chinese medicine composition for improving bone pain in tumor patients and its application in analgesia
  • A traditional Chinese medicine composition for improving bone pain in tumor patients and its application in analgesia
  • A traditional Chinese medicine composition for improving bone pain in tumor patients and its application in analgesia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Take drynaria rhizoma drynariae 15g, sunburnt centipede 2g, epimedium 15g, natural copper 9g, Zhichuanwu 9g and Zhicaowu 9g, add water and use a decoction machine instead of decocting, and prepare a Chinese medicine composition decoction 1 for improving bone pain in tumor patients Bag 150ml is used for the treatment of effect embodiment 1.

Embodiment 2

[0030] Take drynaria fortunei 15g, centipede 2g, epimedium 15g, natural copper 6g, aconitum 3g and aconitum 3g, add water and use a decoction machine to decoct, and the decoction is concentrated to prepare a traditional Chinese medicine combination for improving bone pain in tumor patients Oral liquid.

Embodiment 3

[0032] Take 30g of drynariae, 4g of sunburned centipede, 30g of epimedium, 18g of natural copper, 18g of Zhichuanwu and 18g of Zhicaowu, add water and use a decoction machine to decoct. Filtrate the decoction, concentrate the filtrate, cool to room temperature, add an equal amount of ethanol to precipitate, and let stand; take the supernatant to concentrate, add water to stir, let stand, take the supernatant to concentrate into a clear paste. The clear ointment, sucrose powder, dextrin and ethanol are taken to make granules, and dried to prepare granules of the traditional Chinese medicine composition for improving bone pain of tumor patients.

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Abstract

The invention provides a traditional Chinese medicinal composition with an effect of relieving ostealgia of a tumor patient, and an application of the traditional Chinese medicinal composition in pain-easing. The traditional Chinese medicinal composition with the effect of relieving ostealgia of the tumor patient is prepared from the following raw materials in parts by weight: 15-30 parts of rhizoma drynariae, 2-4 parts of processed scolopendra, 15-30 parts of herba epimedii, 3-18 parts of pyritum, 3-18 parts of processed radix aconite, and 3-18 parts of processed radix aconiti kusnezoffii. The traditional Chinese medicinal composition with the effect of relieving ostealgia of the tumor patient has an effective pain-easing effect in treatment of osseous metastasis of cancer, a synergy curative effect on osseous metastasis, and effects of reliving ostealgia, remarkably lowering the side effect of diphosphonate and greatly improving quality of life and immunity of the patient.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for improving bone pain in tumor patients and its application in analgesia. Background technique [0002] Among the common malignant tumors, lung cancer, breast cancer and prostate cancer often have bone metastases, resulting in intractable pain, dysfunction, pathological fractures, spinal cord compression and hypercalcemia, which make the patients miserable, limited their activities, and life Quality deteriorates. Patients often lose confidence in treatment due to severe pain. [0003] The commonly used methods to treat pain with bone metastases are chemotherapy, radiotherapy, and step-by-step use of analgesic drugs, etc., but the effect on patients with extensive bone metastases is not obvious, and tolerance and addiction are prone to occur. [0004] In recent years, bisphosphonates have been used clinically to inhibit the...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/714A61P35/04A61P29/00A61K33/26A61K35/648A61K31/675
Inventor 徐振晔金长娟鲁叶云吕英罗琴琴王立芳邓海滨周卫东
Owner LONGHUA HOSPITAL SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE
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