Hydrogel dressing for preventing and relieving carsickness

A technology of hydrogel application and deionized water, which is applied in the field of medical auxiliary products, can solve the problems of inconvenient use of essential oil products, many factors that limit the use, and the effect is not long-lasting, and achieves a clear smell, no irritation, and excellent adhesion performance. , good use effect

Inactive Publication Date: 2016-12-21
云南白药集团无锡药业有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Oral medicines often have disadvantages such as toxic side effects and many restrictive factors; essential oil products are inconvenient to use and have short-lasting effects, and have shortcomings such as irritating odor; auxiliary treatment products often fall off and have poor effects during use , increasing the user's psychological and economic burden

Method used

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  • Hydrogel dressing for preventing and relieving carsickness

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] (1) Weigh a certain amount of β-CD, dissolve it in deionized water at 40°C to form a saturated solution, add the essential oil mixture according to the ratio of essential oil: β-CD of 1:8, stir at 40°C for 1 hour, and release Place in the icehouse (4°C) for one day, filter with suction, wash with ether three times, and dry at 40°C for 4 hours to obtain a white powdery essential oil clathrate, which is ready for use;

[0029] (2) Disperse the modified starch in part of the deionized water, heat and stir at 75°C to 90°C, and gelatinize for 30min to make a 10% uniform starch gelatinized product for later use;

[0030] (3) Partially neutralized polyacrylic acid and its sodium polyacrylate copolymer 6g, povidone 2.8g are dispersed in 20g humectant (glycerin), and set aside;

[0031] (4) Disperse 0.3 g of the crosslinking agent glyoxate in a small amount of ethanol and dissolve it for subsequent use;

[0032] (5) Take 22.5g of the essential oil clathrate prepared in step (1)...

Embodiment 2

[0035] (1) Weigh a certain amount of β-CD, dissolve it in deionized water at 40°C to form a saturated solution, add the essential oil mixture according to the ratio of essential oil: β-CD of 1:9, stir at 40°C for 1.5h, put Place in a refrigerator (4°C) for one day, filter with suction, wash with ether three times, and dry at a constant temperature at 40°C for 4 hours to obtain a white powdery essential oil clathrate, which is ready for use;

[0036] (2) Disperse the modified starch in part of the deionized water, heat and stir at 75°C to 90°C, and gelatinize for 30min to make a 10% uniform starch gelatinized product for later use;

[0037] (3) Sodium carboxymethyl cellulose is dissolved in part of deionized water, stirred to form a uniform and stable transparent colloidal liquid, and set aside;

[0038] (4) Partially neutralized polyacrylic acid and its sodium polyacrylate copolymer 6g, povidone 2.8g are dispersed in 20g humectant (glycerin), and set aside;

[0039] (5) Dispe...

Embodiment 3

[0043] (1) Weigh a certain amount of β-CD, dissolve it in deionized water at 40°C to form a saturated solution, add the essential oil mixture according to the ratio of essential oil: β-CD of 1:9, stir at 40°C for 1.5h, put Place in a refrigerator (4°C) for one day, filter with suction, wash with ether three times, and dry at a constant temperature of 45°C for 3 hours to obtain a white powdery essential oil clathrate, which is ready for use;

[0044] (2) Disperse the modified starch in part of the deionized water, heat and stir at 75°C to 90°C, and gelatinize for 30min to make a 10% uniform starch gelatinized product for later use;

[0045] (3) Sodium carboxymethyl cellulose is dissolved in part of deionized water, stirred to form a uniform and stable transparent colloidal liquid, and set aside;

[0046] (4) Disperse 6 g of partially neutralized polyacrylic acid and its sodium polyacrylate copolymer, and 2.8 g of povidone in 16 g of humectant (glycerin), then add 4 g of sorbito...

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Abstract

The invention relates to a medical auxiliary article, in particular to a hydrogel dressing for preventing and relieving carsickness and a preparation method of the hydrogel dressing. The hydrogel dressing provided by the invention comprises a hydrogel layer, a fixing ring and a tying band. The hydrogel layer consists of the following raw material components in parts by weight: 10-30 parts of an essential oil inclusion compound, 1-5 parts of a fresh ginger extract, 5-20 parts of an adhesive, 10-30 parts of a humectant, 1-5 parts of an excipient, 0.2-2 parts of a pH regulator, 0.1-2 parts of a cross-linking agent, 0.5-5 parts of a tackifying agent, 0.1-5 parts of a penetration enhancer, 0.1-1 part of a chelating agent, 50-80 parts of de-ionized water and 5-20 parts of a dispersing agent. The hydrogel dressing disclosed by the invention is convenient to use and is moderate in adhesion performance with skin; the hydrogel dressing is prevented from falling off in a using process, and meanwhile, the hydrogel dressing is free from a painful feeling due to adhesion to skin fine hair when the hydrogel dressing is torn off; and the hydrogel dressing is free from toxic and side effects, capable of effectively preventing allergy, delicate in smell, soft in texture and comfortable to use.

Description

technical field [0001] The invention relates to a medical auxiliary product, in particular to a hydrogel application for preventing and alleviating motion sickness and a preparation method thereof. Background technique [0002] The existing methods for the treatment of motion sickness on the market mainly include oral medicine, essential oil products and some auxiliary treatment products. Oral medicines often have disadvantages such as toxic side effects and many restrictive factors; essential oil products are inconvenient to use and have short-lasting effects, and have shortcomings such as irritating odor; auxiliary treatment products often fall off and have poor effects during use , increasing the user's psychological and economic burden. Contents of the invention [0003] Aiming at the above-mentioned problems existing in existing motion sickness prevention and treatment products, the present invention provides a hydrogel application for preventing and alleviating moti...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/70A61P1/08
Inventor 张睿曹晓军刘跃赵晓亮陆晔晖
Owner 云南白药集团无锡药业有限公司
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