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Microspheres with tea extract and complex wrapped and application thereof in natural edible toothpaste

A technology of tea extracts and complexes, which is applied in the application of natural edible toothpaste and the field of microspheres wrapped with tea extract complexes, can solve the problems of toothpaste paste discoloration and loss of activity, so as to prevent dental caries and improve dental health. Stability, simple and feasible production process

Active Publication Date: 2016-12-07
广州悦创实业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, when tea extract is added to toothpaste, tea polyphenols will be oxidized into theaflavins, which will lead to discoloration and loss of activity of the toothpaste paste.

Method used

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  • Microspheres with tea extract and complex wrapped and application thereof in natural edible toothpaste
  • Microspheres with tea extract and complex wrapped and application thereof in natural edible toothpaste
  • Microspheres with tea extract and complex wrapped and application thereof in natural edible toothpaste

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Experimental program
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Effect test

Embodiment 1～5

[0045] (1) Dissolve the tea extract in a phosphate buffer solution with a pH value of 7, prepare a 10% wt tea extract aqueous solution, and add 2% wt zinc lactate solution under stirring until the precipitation is complete; collect the tea extract Thin-zinc ion complex, dried at 50°C.

[0046] (2) PLGA is dissolved in 20 times the amount (mass volume ratio, g / ml, 1gPLGA, plus 20ml of ethanol) of ethanol to form a PLGA solution, and vitamin E is added;

[0047] (3) Using a fluidized bed process, the PLGA mixed solution is sprayed onto the surface of the complex of tea extract and zinc ions to form microspheres wrapped with a film layer of tea extract and metal ion complexes, and the fluidized bed The inlet air temperature is 40°C, and the feed rate is 60ml / min.

[0048] The formula of toothpaste that the present invention adopts is following table, and preparation technology is as follows:

[0049] 1) Weigh the friction agent and thickener according to the formula, stir them ev...

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Abstract

The invention discloses microspheres with a tea extract and a complex wrapped and application of the microspheres in natural edible toothpaste. The microspheres with the tea extract and the complex wrapped is obtained by wrapping the tea extract and the metal ion complex with a lactic acid / glycolic acid copolymer. The invention further provides the natural edible toothpaste for children with the tea extract and the metal ion complex as main functional ingredients, the tea extract and the metal complex stably exist in the formula, and therefore the product has the quite effects of resisting bacteria, inhibiting dental plaque, preventing decayed teeth, making breath fresh, cleaning the oral cavity and making the gingiva healthy.

Description

technical field [0001] The invention relates to the field of oral care products, in particular to a microsphere wrapped with tea extract complex and its application in natural edible toothpaste. Background technique [0002] Caries is the most common oral problem in children's teeth. The currently recognized pathogenesis of dental caries is the triple theory, that is, the three factors of bacteria, food and host work together to lead to the occurrence of dental caries. Simply put, certain bacteria (mainly Streptococcus mutans and Actinobacillus actinomycetes) decompose the food left in the mouth to produce acid, which leads to the demineralization of tooth enamel, resulting in dental caries. [0003] The occurrence of dental caries in childhood varies according to the timing and shape of tooth eruption. After the deciduous teeth erupt in infants, infants can easily cause dental caries because infants hold a feeding bottle containing sweet milk or sweet drinks for a long ti...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61K8/85A61Q11/00
CPCA61K8/85A61K8/97A61K2800/41A61Q11/00
Inventor 江山张海
Owner 广州悦创实业有限公司
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