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Anti-oxidant oral nursing composition

An oral care and composition technology, applied in the field of oral care, can solve the problems of oral composition discoloration, complex molecular structure, loss of reducibility of polyphenols, etc., and achieve the effect of reducing discoloration

Active Publication Date: 2016-11-09
HAWLEY & HAZEL CHEMICAL CO (ZHONGSHAN) LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, natural products usually have a complex molecular structure. For example, the molecular structure of polyphenolic compounds contains multiple phenolic hydroxyl groups, so they are easily oxidized to form complex quinones, causing polyphenols to lose their original reducing properties, and lead to oral combination. discoloration

Method used

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  • Anti-oxidant oral nursing composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] Embodiment 1: Calcium chloride can improve the stabilizing effect of stannous compound to tea polyphenols

[0073] This example shows that the alkaline earth metal ion source itself has no antioxidant effect, but it can improve the stabilizing effect of stannous compounds on tea polyphenols. In this embodiment, the source of alkaline earth metal ions is calcium chloride.

[0074] Toothpaste was prepared as follows.

[0075] Table 1

[0076]

[0077]

[0078] When the toothpaste (formula 1-1) containing tea polyphenols and calcium chloride was placed at room temperature for one month, it was observed that the overall yellowing of the toothpaste ( figure 1 A), it can be seen that the tea polyphenols in the toothpaste are severely oxidized, resulting in discoloration of the toothpaste paste. Therefore, the effect of adding calcium chloride alone on stabilizing tea polyphenols is relatively poor, and has no obvious antioxidant effect.

[0079] When the toothpaste ...

Embodiment 2

[0081] Embodiment 2: the free calcium ion that different sources of soluble calcium ions discharge can all improve the stabilizing effect of stannous fluoride on tea polyphenols

[0082] Oral care compositions were prepared as follows.

[0083] Table 2

[0084]

[0085]

[0086] Place the toothpastes of the above formulas 3-1, 3-2, 3-3, 3-4, 3-5, 3-6, and 3-7 at room temperature, 40°C and 50°C respectively, and place them for one month Test the EGCG content therein respectively to evaluate the stability of tea polyphenols. The test results are shown in Table 3 and Table 4.

[0087] The effect of each formulation in Table 3 and Table 2 on stabilizing tea polyphenols.

[0088]

[0089] The results in Table 3 show that the alkali metal ion source taking the calcium ion source as an example can improve the stabilizing effect of stannous compounds on tea polyphenols, and has better stability of tea polyphenols than the reference toothpaste using stannous compounds alone...

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Abstract

The invention relates to the field of oral nursing, in particular to an oral nursing composition containing polyphenol compounds, a stannous ion source and a soluble non-antioxidant alkaline earth metal ion source and a method for reducing oxidation of the polyphenol compounds in the oral nursing composition containing the stannous ion source and the polyphenol compounds.

Description

technical field [0001] The invention relates to the field of oral care, in particular to an anti-oxidative oral care composition comprising polyphenolic compounds, and a method for reducing the oxidation of the polyphenolic compounds in the oral care composition comprising polyphenolic compounds. Background technique [0002] Plant extracts can be included in the oral composition to provide oral health functions, such as removing bad breath or bad smell, preventing dental caries, reducing dental plaque, inhibiting the reproduction of oral bacteria, inhibiting periodontitis, and scavenging free radicals. A variety of plant extracts have been used in oral compositions such as toothpaste, such as tea extracts, Chinese herbal medicine extracts, and the like. Rich in various natural products such as polyphenolic compounds in plant extract ingredients. However, natural products usually have a complex molecular structure. For example, the molecular structure of polyphenolic compou...

Claims

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Application Information

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IPC IPC(8): A61K8/19A61K8/34A61Q11/00
CPCA61K8/19A61K8/347A61K2800/522A61Q11/00
Inventor 谢森奎华淑贞
Owner HAWLEY & HAZEL CHEMICAL CO (ZHONGSHAN) LTD
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