High-intensity focused ultrasound three-dimensional temperature field simulation algorithm based on Gauss function convolution

Abstract

The present invention relates to an algorithm capable of rapidly calculating and simulating a three-dimensional temperature field caused by high-intensity focused ultrasound at biological soft tissues, and specifically relates to a high-intensity focused ultrasound three-dimensional temperature field simulation algorithm based on Gauss function convolution. The algorithm comprises the following steps of (1) calculating a sound field at a high-intensity focused ultrasound focus by utilization of the sound radiation principle; (2) performing convolution operation on an original temperature graph generated by the sound field on the biological tissues and the Gauss function; and (3) calculating a time-dependent three-dimensional temperature field at the ultrasound focus. Operand of the Gauss function is little, operation speed is fast, and the time-dependent three-dimensional temperature field caused by the high-intensity focused ultrasound is real-time temperature simulation. The algorithm is applied to real-time temperature monitoring during a high-intensity focused ultrasound tumor ablation treatment process, waste heat during the ablation process and a heat source position can be controlled, maximum damage to tumors during the treatment process is optimized, and damage to peripheral healthy cells is prevented.

Description

technical field [0001] The invention relates to an algorithm capable of quickly calculating and simulating a three-dimensional temperature field caused by high-intensity focused ultrasonic waves in biological soft tissues, especially a high-intensity focused ultrasonic three-dimensional temperature field simulation algorithm based on Gaussian function convolution. Background technique [0002] High-intensity focused ultrasound (HIFU) tumor ablation technology is a new tumor treatment method that has become popular in recent years. Its biggest feature is that it uses the high-intensity ultrasound emitted by the external ultrasound transducer to pass through the skin non-invasively and form an ultrasound focus on the tumor in the body. The temperature at the focal point rises instantaneously, causing coagulation and necrosis of the surrounding tumor tissue, which eventually forms scars or is absorbed by metabolism. However, due to the residual heat of the focus or inaccurate ...

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Problems solved by technology

However, due to the large amount of calculation of numerical calculation methods such as finite element analysis, it is difficult to simulate the temperature field in real time.

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