Absorbable wound buffer dressing

Abstract

The invention belongs to the field of biomedical materials, and particularly relates to an absorbable wound buffer dressing. The absorbable wound buffer dressing is prepared by mixing carboxymethyl starch with body fluid. A preparation method of the absorbable wound buffer dressing comprises the steps that the carboxymethyl starch is dissolved into a water medium, and after the pH value is regulated, an emulsification cross-linking reaction, extraction washing and drying sterilization are conducted to obtain carboxymethyl starch particles; the carboxymethyl starch particles are fully mixed with the body fluid, and then the absorbable wound buffer dressing is obtained. The absorbable wound buffer dressing can achieve the protection and external force buffer effects on wounds, is beneficial for wound healing, good in biocompatibility, capable of directly acting on the general bleeding wounds, the deep bleeding wounds and the bleeding wound of the parts where surgical operation is difficult to reach, easy and convenient to use and capable of being degraded and absorbed in a body and does not need to be removed from the wounds after being used. The dressing is easy and convenient to use and has the important significance on development of new biomedical materials.

Description

technical field [0001] The invention belongs to the field of biomedical materials, in particular to an absorbable wound buffer dressing. Background technique [0002] The types of dressings for wounds include powder dressings, foam dressings, porous body dressings or non-woven dressings, etc., and each dressing has its advantages and disadvantages. On the powder type dressing, its advantage is that the area of ​​action is large, so it can cover a wide range of wounds, but the disadvantage is that it is easy to form agglomerates and is difficult to remove. For foam dressings, the advantage is that it can adjust the wetness of the wound to avoid physical damage to the wound. The disadvantage is that it only acts on the surface of the wound, and its effect on cavity-type wounds is limited. The advantage of the porous body dressing is that it can absorb a large amount of body fluid, avoid wound inflammation and ulceration, and create a wet healing environment. The disadvantage ...

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Problems solved by technology

[0004] The above-mentioned wound dressing needs to be removed from the wound by removing the carrier after use. It cannot be applied to deep wounds and bleeding wounds that are difficult to reach during surgical operations, and the related materials cannot be degraded and absorbed in the body.

At present, the hemostatic materials used clinically mainly include fibrin glue, collagen, gelatin sponge and cellulose hemostatic materials. These materials have achieved good results in animal experiments and clinical applications, but there are also some shortcomings: collagen The raw material is derived from animal tissue, which is a heterogeneous protein, which is prone to rejection and has potential allergies; gelatin absorbs slowly, usually for more than 4 weeks, which will increase the risk of wound infection; cellulose, the human body lacks enzymes to degrade it , the degradation time is long, which may bring side effects such as infection to the patient

[0006] At present, there are no relevant reports on wound dressings made of carboxymethyl starch

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