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Pharmaceutical composition for treating thyroid cancer postoperative recurrent thyroid nodule

A technology for thyroid nodules and thyroid cancer, applied in the field of traditional Chinese medicine, can solve the problem of high recurrence probability, achieve the effects of convenient administration, reduce the burden and pain of patients, and improve the quality of life

Inactive Publication Date: 2016-08-10
QINGDAO YUNTIAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is a higher chance of recurrence at the original surgical site after surgery

Method used

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  • Pharmaceutical composition for treating thyroid cancer postoperative recurrent thyroid nodule
  • Pharmaceutical composition for treating thyroid cancer postoperative recurrent thyroid nodule
  • Pharmaceutical composition for treating thyroid cancer postoperative recurrent thyroid nodule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1 capsule

[0041] Prescription: 20 parts of Cat's Claw, 15 parts of Pteris, 15 parts of Rhizoma Polygonatum, 12 parts of Pseudostellaria, 6 parts of Silkworm, 8 parts of White Mustard Seed, 10 parts of Citron, 10 parts of Limonium, 4 parts of Chenpi, 15 parts of Cuscuta 15 parts, 15 parts of gerbera, 24 parts of bitter fennel.

[0042] Preparation method: (1) take gerbera, bitter rosin, white mustard seed, and citron according to the prescription, grind them into particles with an average particle size of 45 μm, add 7 times the amount of 60% ethanol aqueous solution, and use ultrasonic extraction. After the ultrasonic extraction is completed, Collect the filter residues after water extraction of gerbera, bitter rosa, white mustard seed, and citron, combine the filtrates, concentrate under reduced pressure to a relative density of 1.18 (measured at 60°C), and obtain extract A for future use. The extraction conditions include: ultrasonic The power is 150-160W...

Embodiment 2

[0044] Embodiment 2 capsules

[0045] Prescription: 22 parts of Cat's Claw, 16 parts of Pteris, 18 parts of Rhizoma Polygonatum, 10 parts of Pseudostellaria, 8 parts of Silkworm, 10 parts of White Mustard Seed, 12 parts of Citron, 15 parts of Limonium, 6 parts of Chenpi, 12 parts of Cuscuta 16 parts, 16 parts of gerbera, 20 parts of bitter fennel.

[0046] Preparation method: (1) according to the prescription, take gerbera, balsamic, white mustard seed, and citron, grind them into particles with an average particle size of 55 μm, add 6 times the amount of 60% ethanol aqueous solution, and use ultrasonic extraction. After the ultrasonic extraction is completed, Collect the filter residues after water extraction of gerbera, bitter rosa, white mustard seed, and citron, combine the filtrates, concentrate under reduced pressure to a relative density of 1.18 (measured at 60°C), and obtain extract A for future use. The extraction conditions include: ultrasonic The power is 150-160W,...

Embodiment 3

[0048] Embodiment 3 capsules

[0049] Prescription: 20 parts of Cat's Claw, 12 parts of Pteris, 18 parts of Polygonatum, 10 parts of Pseudostellaria, 6 parts of Silkworm, 12 parts of White Mustard Seed, 12 parts of Citron, 12 parts of Limonium, 5 parts of Tangerine Peel, 15 parts of Cuscuta 15 parts, 15 parts of gerbera, 20 parts of bitter fennel.

[0050] Preparation method: (1) take gerbera, bitter rosin, white mustard seed, and citron according to the prescription, grind them into particles with an average particle size of 45 μm, add 7 times the amount of 60% ethanol aqueous solution, and use ultrasonic extraction. After the ultrasonic extraction is completed, Collect the filter residues after water extraction of gerbera, bitter rosa, white mustard seed, and citron, combine the filtrates, concentrate under reduced pressure to a relative density of 1.17 (measured at 60°C), and obtain extract A for future use. The extraction conditions include: ultrasonic The power is 150-16...

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Abstract

The invention belongs to the field of traditional Chinese medicine and specifically relates to a pharmaceutical composition for treating a thyroid cancer postoperative recurrent thyroid nodule and a preparation method thereof. The pharmaceutical composition is prepared from the following medicinal materials according to certain weight ratio: radix ranunculi ternati, herba pteridis multifidae, rhizoma polygonati, radix pseudostellariae, white muscardin silkworm, semen brassicae, citrus medica, limonium sinense, pericarpium citri reticulatae, semen cuscutae, herba gerberae piloselloidis and physalis angulata. Through the compatibility of the medicinal materials, the composition has the efficacies of detoxifying, diminishing swelling, eliminating stagnation, reducing phlegm, tonifying qi, nourishing yin, removing dampness by dieresis, clearing away turbidness and strengthening the body resistance to eliminate pathogenic factors, have multi-target and mult-isystem regulation effects on a patient who suffers from the thyroid cancer postoperative recurrent thyroid nodule with qi deficiency and yin deficiency, and can effectively improve traditional Chinese medicine clinical symptoms of the thyroid cancer postoperative patient, decrease the thyroid nodule, and reduce the serum thyroglobulin level, and thus the recurrence and the metastasis of the cancer are prevented and the life quality of the patient is improved.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for treating recurrent thyroid nodules after thyroid cancer surgery and a preparation method thereof. Background technique [0002] Thyroid cancer is a common malignant tumor of the neck, and its incidence is increasing year by year in my country. At present, the prevalence of thyroid nodules in the Chinese population is 18.6%, of which malignant nodules (i.e. thyroid cancer) account for 5% to 10%, and the pathological types are mainly divided into papillary carcinoma, follicular carcinoma, undifferentiated carcinoma, and medullary carcinoma. cancer etc. In addition to the development and improvement of diagnostic techniques, improper diet, excessive mental stress, and radiation exposure may all be the cause of disease. [0003] Currently, surgery is the best treatment for thyroid cancer. However, there is a higher chance of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61K9/48A61P35/00A61P43/00A61K35/64
CPCA61K36/8969A61K9/4808A61K35/63A61K36/11A61K36/185A61K36/28A61K36/31A61K36/36A61K36/39A61K36/71A61K36/752A61K36/81A61K2236/39A61K2236/51A61K2236/53A61K2236/331A61K2236/333A61K2300/00
Inventor 王传秀
Owner QINGDAO YUNTIAN BIOTECH
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