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Biological material applied to operative skin incision and infectious and non-infectious wound surfaces and application thereof

A skin incision, non-infectious technology, used in skin care preparations, skin diseases, drug combinations, etc., can solve problems such as poor flexibility of chitosan films, achieve the effects of reducing pain, preventing wound infection, and shortening time

Inactive Publication Date: 2016-07-06
CHENGDU SUPERWELL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] The invention provides a biological material and its application for surgical skin incisions, infectious and non-infectious wounds, and solves the problem of poor flexibility of the existing chitosan film

Method used

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  • Biological material applied to operative skin incision and infectious and non-infectious wound surfaces and application thereof
  • Biological material applied to operative skin incision and infectious and non-infectious wound surfaces and application thereof
  • Biological material applied to operative skin incision and infectious and non-infectious wound surfaces and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0064] This embodiment provides a biological material for surgical skin incisions, infectious and non-infectious wounds, which is composed of the following components in weight ratio: bacterial cellulose 0.05%, guanidyl chitosan quaternary ammonium salt 3%, Glycerin is 5%, the balance is water.

[0065] The biological material used in surgical skin incisions, infectious and non-infectious wounds of this embodiment is prepared by the following steps:

[0066] (1) Take the bacterial cellulose, rinse the wet membrane repeatedly with purified water or distilled water at room temperature until the pH value is 6, then add purified water at a ratio of 1%, stir evenly with a glass rod, and then crush it with a tissue masher Into a uniform dispersion;

[0067] (2) Pour the bacterial cellulose dispersion obtained in step (1) into the batching tank, then add purified water according to 75% of the total batching amount, and then add the quaternary guanidine chitosan ammonium salt, first vacuumi...

Embodiment 2

[0070] This embodiment provides a biological material for surgical skin incisions, infectious and non-infectious wounds, which is composed of the following components in weight ratio: bacterial cellulose 0.01%, guanidyl chitosan quaternary ammonium salt 5%, Glycerin 1%, the balance is water.

[0071] The biological material used in surgical skin incisions, infectious and non-infectious wounds of this embodiment is prepared by the following steps:

[0072] (1) Take bacterial cellulose, rinse the wet membrane repeatedly with purified water or distilled water at room temperature to pH 5, then add purified water at a ratio of 2%, stir evenly with a glass rod, and then crush it with a tissue masher Into a uniform dispersion;

[0073] (2) Pour the bacterial cellulose dispersion obtained in step (1) into the batching tank, then add purified water according to 75% of the total batching amount, and then add the quaternary guanidine chitosan ammonium salt, first vacuumize to 0.08 When the pr...

Embodiment 3

[0076] This embodiment provides a biological material for surgical skin incisions, infectious and non-infectious wounds, which is composed of the following components in weight ratio: bacterial cellulose 0.1%, guanidino chitosan quaternary ammonium salt 0.5%, Glycerin 8%, the balance is water.

[0077] The biological material used in surgical skin incisions, infectious and non-infectious wounds of this embodiment is prepared by the following steps:

[0078] (1) Take the bacterial cellulose, rinse the wet membrane repeatedly with purified water or distilled water at room temperature until the pH value is 7, then add purified water at a ratio of 0.5%, stir evenly with a glass rod, and then crush it with a tissue masher Into a uniform dispersion;

[0079] (2) Pour the bacterial cellulose dispersion obtained in step (1) into the batching tank, then add purified water according to 75% of the total batching amount, and then add the quaternary guanidine chitosan ammonium salt, first vacuum...

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Abstract

The invention discloses a biological material applied to an operative skin incision and infectious and non-infectious wound surfaces and belongs to the field of biological materials and application. The biological material is composed of the following components in weight proportion: 0.01-5% of bacterial cellulose, 0.5-8% of guanidyl chitosan quaternary ammonium salt, 1-10% of glycerol, 0-10% of matrix and the balance of water. The invention also discloses application of the biological material in preparation of medical equipment biological dressing and cosmetics. The biological material disclosed by the invention overcomes the defects of a chitosan membrane of poor flexibility and limited used parts, has good film forming characteristic of guanidyl chitosan quaternary ammonium salt and also can be applied to parts, such as cavities and canals, which are inconvenient to smear during administration, so that pain caused by smearing is reduced, and comfort of the wound surface is good.

Description

Technical field [0001] The invention relates to the field of biological materials and applications, in particular to a biological material used for surgical skin incisions, infectious and non-infectious wounds and applications thereof. Background technique [0002] Dressing refers to accessory materials used in addition to the main material of the article. Traditional dressings mainly refer to medical textiles. Common traditional dressings include dry gauze and oil gauze. The common functions of traditional dressings are: a. Wrap supplies: materials used to cover sores, wounds or other damages (such as ointment, gauze, synthetic fiber cloth, plastic film non-stick gauze); b. Antiseptic for treating pain or wound Or compresses soaked in antibiotic solution. For example, dry gauze can play a role in covering the wound; oil gauze contains petrolatum or triglycerides, which can play a role in not adhering to the wound. [0003] The advantages of traditional dressings are: cheap, eas...

Claims

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Application Information

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IPC IPC(8): A61L26/00A61K8/73A61Q19/00A61Q19/02A61Q19/08A61P17/10A61P17/02
CPCA61L26/0023A61K8/731A61K8/736A61L26/0061A61L26/008A61Q19/00A61Q19/02A61Q19/08C08L1/02C08L5/08
Inventor 敬锡志
Owner CHENGDU SUPERWELL TECH CO LTD
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