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Traditional Chinese medicine composition for treating polymyositis and preparation method and application of traditional Chinese medicine composition for treating polymyositis

A composition and multiple-occurrence technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of large side effects and high recurrence rate, and achieve the effect of less toxic side effects, less recurrence, and simple prescriptions

Inactive Publication Date: 2016-06-22
王维娜
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, glucocorticoids are mainly used for the treatment of polymyositis, which has relatively large side effects and a high recurrence rate

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A traditional Chinese medicine composition for treating polymyositis, which is composed of the following raw materials according to weight parts: 18 parts of Coptis chinensis, 6 parts of Beidougen, 12 parts of pork ribs, 18 parts of Zoumafeng, 11 parts of Epimedium, 4 parts of red peony root parts, 5 parts of ephedra, 9 parts of silkworm sand, and 3 parts of Qianrihong.

[0018] The preparation method of the traditional Chinese medicine composition for the treatment of polymyositis described in the present embodiment, the steps are as follows:

[0019] 1) Weigh Coptis chinensis, Beidougen, Ribguling and Zoumafeng, pulverize and mix, add 7 times the amount of 90% concentration ethanol solution, heat and reflux for 3 hours, filter to obtain the first extract, and add the filter residue to 5 times of 90% concentration ethanol solution, heated and refluxed for extraction for 1 h, filtered to obtain the second extract, and the first extract and the second extract were combin...

Embodiment 2

[0023] A traditional Chinese medicine composition for treating polymyositis, which is composed of the following raw materials according to weight parts: 19 parts of Coptis chinensis, 9 parts of Beidougen, 12 parts of pork ribs, 18 parts of Zoumafeng, 12 parts of Epimedium, 6 parts of red peony root parts, 6 parts of ephedra, 10 parts of silkworm sand, and 3 parts of Qianrihong.

[0024] The preparation method of the traditional Chinese medicine composition for the treatment of polymyositis described in the present embodiment, the steps are as follows:

[0025] 1) Weigh Coptis chinensis, Beidougen, Ribguling and Zoumafeng, pulverize and mix, add 8 times the amount of 90% concentration ethanol solution, heat and reflux for extraction for 3 hours, filter to obtain the first extract, and add the filter residue to 5 double the amount of 90% concentration ethanol solution, heated and refluxed for extraction for 1.5h, filtered to obtain the second extract, and the first extract and t...

Embodiment 3

[0029] A traditional Chinese medicine composition for treating polymyositis, comprising the following raw materials in parts by weight: 19 parts of Coptis chinensis, 7 parts of Beidougen, 14 parts of Pork Ribs, 19 parts of Zouma Feng, 12 parts of Epimedium, 5 parts of Red Peony parts, 5 parts of ephedra, 11 parts of silkworm sand, and 4 parts of Qianrihong.

[0030] The preparation method of the traditional Chinese medicine composition for the treatment of polymyositis described in the present embodiment, the steps are as follows:

[0031] 1) Weigh Coptis chinensis, Beidougen, Ribguling and Zoumafeng, pulverize and mix, add 8 times the amount of 90% ethanol solution, extract under reflux for 3.5 hours, filter to obtain the first extract, and add the filter residue again 6 times the amount of 90% concentration ethanol solution, heated and refluxed for extraction for 1.5h, filtered to obtain the second extract, and the first extract and the second extract were combined to obtain...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating polymyositis. The traditional Chinese medicine composition for treating polymyositis comprises, by weight, 18-20 parts of Rhizoma Coptidis, 6-9 parts of Rhizoma Menispermi, 12-15 parts of Cortex Fissistigmatis Bracteolati Radicis, 18-20 parts of herb of laciniate blumea, 11-13 parts of Herba Epimedii, 4-6 parts of Radix Paeoniae Rubra, 5-6 parts of Herba Ephedrae, 9-12 parts of Feculae Bombycis and 3-5 parts of Gomphrena globosa L.. The invention further provides a preparation method of the traditional Chinese medicine composition for treating polymyositis. The traditional Chinese medicine composition for treating polymyositis is simple in formula, remarkably effective in treatment of polymyositis by being as high as 98.5% in total effective rate and less prone to causing relapse after cure, and is lower in treatment cost and less in toxic or side effect than glucocorticoid, thereby being beneficial to health of patients.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating polymyositis, a preparation method and application thereof. Background technique [0002] Polymyositis is an inflammatory myopathy with muscle weakness, muscle atrophy, and myalgia as the main manifestations. If the disease is limited to the muscles, it becomes polymyositis, and if the skin is also involved, it is called dermatomyositis. Mostly subacute onset, can occur at any age, more common in middle-aged and older, and slightly more women. The clinical manifestations of this disease are diverse due to the different scope of involvement and the large differences in associated diseases. Usually, the disease peaks within a few weeks to several months, with generalized muscle weakness, and in severe cases, respiratory muscle weakness, which is life-threatening. At present, glucocorticoids are mainly used for th...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61P21/00A61P29/00A61K35/64
CPCA61K35/63A61K36/17A61K36/185A61K36/21A61K36/28A61K36/296A61K36/59A61K36/65A61K36/71A61K36/718A61K2236/39A61K2236/333A61K2236/331A61K2300/00
Inventor 王维娜
Owner 王维娜
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