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A method and device for quantifying myocardial T1

A technology of myocardium and heart, applied in the field of myocardial T1 quantification and devices, can solve the problems of many times of breath-holding, long acquisition time, low patient comfort, etc., and achieve the effect of preventing deviation and reducing time waste

Active Publication Date: 2018-10-26
SHENZHEN INST OF ADVANCED TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In the above method, each breath-hold can only collect a single-layer image, and multiple breath-holds are required to collect multi-layer images. The number of breath-holds is large, the acquisition time is long, and the patient's comfort is low.

Method used

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  • A method and device for quantifying myocardial T1
  • A method and device for quantifying myocardial T1
  • A method and device for quantifying myocardial T1

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Experimental program
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Embodiment 1

[0031] figure 1 Shows a flowchart of an embodiment of the method according to the present application, including:

[0032] Step 102: After the ECG gated trigger delay, apply a non-layer selective inversion pulse, and use the radial sampling track fast spoiled gradient echo small-angle excitation sequence to perform real-time interlaced acquisition of at least two layers of images to capture the signal The reverse recovery process.

[0033] Apply a non-layer-selected inversion pulse (IR), and then use the fast spoiler gradient echo small-angle excitation sequence (turbo-flash) of the radial sampling trajectory for real-time acquisition to sample the signal inversion recovery process, turbo- Flash adopts multi-layer interleaved acquisition mode, which can collect multi-layer images after one reversal pulse, such as figure 2 Shown.

[0034] Radial sampling gradient waveform diagram such as image 3 Shown. In radial sampling, each sampling line passes through the center of K space. T...

Embodiment 2

[0044] Figure 7 It is a schematic structural diagram of an embodiment of the device according to the present application, including: a data acquisition module, a selection module, an image reconstruction module, and a fitting module.

[0045] The data acquisition module is used to apply a non-layer selective inversion pulse after the ECG gated trigger delay, and use the fast spoiled gradient echo small-angle excitation sequence of the radial sampling trajectory to perform real-time interlaced acquisition of at least two layers of images, The inversion recovery process of the captured signal. In one embodiment, it is also used to apply a non-slice-selected inversion pulse, and use the fast spoiler gradient echo small-angle excitation sequence of the radial sampling trajectory for real-time acquisition to sample the signal inversion recovery process. The rapid spoiled gradient echo small-angle excitation sequence of the radial sampling trajectory adopts a multi-layer interlaced ac...

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Abstract

The invention discloses a myocardium T1 quantifying method. The method includes the steps that after electrocardiograph gating trigger delay, non-layer-selection inversion pulses are applied; real-time interlaced collection of at least two layers of images is carried out with a fast spoiled gradient echo low-angle shot sequence of a radial sampling trajectory, and the inversion recovery process of signals is captured; a sampling line in diastole is selected to serve as a K space center line; with the selected sampling line as the center, the sampling line is symmetrically selected to carry out image reconstruction according to the size of a reconstruction window; a T1 quantifying graph is fitted with restructured images. The invention further discloses a device based on the method. By means of the method and the device, multiple layers of T1 quantifying images can be collected in one time of breathholding, the whole heart can be covered in two or three times of breathholding, and thus time waste and patient discomfort caused by breathholding are reduced.

Description

Technical field [0001] The field of cardiovascular imaging in this application specifically relates to a method and device for quantifying myocardial T1. Background technique [0002] Cardiovascular magnetic resonance imaging (CMR) is a non-invasive imaging technique that can evaluate the function, morphology, and structure of the cardiovascular system. The quantification of myocardial T1 value can be used in the diagnosis of myocardial infarction, myocardial fibrosis and other diseases. Due to the limitation of the acquisition time by heart beat and breathing movement, the T1 quantification of in vivo myocardium is still very challenging. [0003] The commonly used methods of measuring myocardial T1 value are as follows: [0004] (1) MOLLI (Modified Look-Locker inversion recovery): After the inversion pulse (IR), use bssfp (balance steady state free precession) sequence imaging at different delay (TI) times, and merge the data collected multiple times into One set to fit the T1 v...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/055A61B5/00
CPCA61B5/055A61B5/7207
Inventor 刘新朱燕杰钟耀祖郑海荣
Owner SHENZHEN INST OF ADVANCED TECH
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