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Peach seed-safflower Siwu granule originated from peach seed-safflower Siwu decoction, and preparation method thereof

A technology of Taohong Siwu Decoction and Taohong Siwu, which can be applied to medical preparations containing active ingredients, anti-inflammatory agents, and drug combinations, etc., can solve the problems of contravention of decoction-free Chinese medicine granules, complex mechanism, and overall curative effect.

Inactive Publication Date: 2016-06-01
ANHUI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantage of other decoction-free granules is that decoction-free Chinese medicine granules violate the principle of co-decoction of traditional Chinese medicine. A series of blends of active ingredients
The co-decoction of Chinese herbal medicines has the functions of interfering, assisting, and opposing, which can enhance the curative effect and reduce toxicity or adverse reactions. The decoction-free traditional Chinese medicine granules do not have the group decoction process, and the overall curative effect of the formula may be affected.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0017] Weigh 90 grams of angelica, 60 grams of Chuanxiong, 90 grams of white peony, 120 grams of Rehmannia glutinosa, 60 grams of safflower, and 90 grams of peach kernels. Add water 8 times each time, and decoct for 1.5 hours each time; extract the medicinal liquid, combine the medicinal liquid, filter, and dry under reduced pressure to a concentrated solution with a relative density of 1.00~1.15; Spray drying is carried out under the conditions of tuyere temperature 150-210°C and air outlet temperature 70-120°C to obtain spray-dried medicinal powder; according to 1 part of medicinal powder: 4.5 parts of sugar powder: 0.5 part of dextrin, add sugar powder and dextrin to 70 % ethanol as a wetting agent, made of soft materials, passed through a 14-mesh sieve to make wet granules, dried under reduced pressure below 60°C, passed through a 20-mesh sieve for granulation, and packaged to obtain Taohong Siwu granules.

specific Embodiment 2

[0018] Weigh 110 grams of angelica, 60 grams of Chuanxiong, 90 grams of white peony, 120 grams of Rehmannia glutinosa, 60 grams of safflower, and 90 grams of peach kernels. Add water 8 times each time, and decoct for 1.5 hours each time; extract the medicinal liquid, combine the medicinal liquid, filter, and dry under reduced pressure to a concentrated solution with a relative density of 1.00~1.15; Spray drying is carried out under the conditions of tuyere temperature 150-210°C and air outlet temperature 70-120°C to obtain spray-dried medicinal powder; according to 1 part of medicinal powder: 4.5 parts of sugar powder: 0.5 part of dextrin, add sugar powder and dextrin to 70 % ethanol as a wetting agent, made of soft materials, passed through a 14-mesh sieve to make wet granules, dried under reduced pressure below 60°C, passed through a 20-mesh sieve for granulation, and packaged to obtain Taohong Siwu granules.

specific Embodiment 3

[0019] Weigh 90 grams of angelica, 80 grams of Chuanxiong, 90 grams of white peony, 120 grams of Rehmannia glutinosa, 60 grams of safflower, and 90 grams of peach kernels. Add water 8 times each time, and decoct for 1.5 hours each time; extract the medicinal liquid, combine the medicinal liquid, filter, and dry under reduced pressure to a concentrated solution with a relative density of 1.00~1.15; Spray drying is carried out under the conditions of tuyere temperature 150-210°C and air outlet temperature 70-120°C to obtain spray-dried medicinal powder; according to 1 part of medicinal powder: 4.5 parts of sugar powder: 0.5 part of dextrin, add sugar powder and dextrin to 70 % ethanol as a wetting agent, made of soft materials, passed through a 14-mesh sieve to make wet granules, dried under reduced pressure below 60°C, passed through a 20-mesh sieve for granulation, and packaged to obtain Taohong Siwu granules.

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Abstract

The invention relates to a peach seed-safflower Siwu granule containing medicinal materials like peach seed, safflower, Chinese angelica, common peony root, prepared rehmannia root and Ligusticum wallichii, and a preparation method thereof, belonging to the technical field of Chinese pharmaceutical manufacturing. The preparation method comprises the following steps: crushing peach seed, safflower, Chinese angelica, common peony root, prepared rehmannia root and Ligusticum wallichii, then adding water for decoction, combining two obtained decoctions, and then successively carrying out filtering, pressure-reduced concentration and spray drying so as to obtain dry powder; and then adding sugar and dextrin and then successively carrying out uniform mixing, granulation, drying and size finishing so as to obtain the peach seed-safflower Siwu granule. According to the invention, a spray drying manner is employed; product quality can be improved; quality indexes like the particle size distribution, moisture content, biological activity and dissolvability of drugs are controlled; and product purity and production efficiency are enhanced.

Description

technical field [0001] The invention relates to a Taohong Siwu granule derived from Taohong Siwu Decoction and a preparation method thereof, belonging to the technical field of traditional Chinese medicine preparations. Background technique [0002] Taohong Siwu Decoction originated from the "Golden Mirror of Medicine" by Wu Qian of the Qing Dynasty. It is composed of peach kernels, safflower, angelica, white peony root, rehmannia glutinosa, and Chuanxiong. It is one of the classic prescriptions for promoting blood circulation and removing blood stasis in traditional Chinese medicine. In the prescription, peach kernels and safflower have mild effects of promoting blood circulation, combined with Siwu Decoction to nourish blood and strengthen the body, the whole prescription is properly compatible, so that blood stasis can be removed, new blood can be generated, and qi can be smoothed. Removing blood stasis and promoting regeneration are the remarkable characteristics of this ...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K9/16A61P15/00A61P29/00A61P37/04A61P19/08
Inventor 彭代银陈卫东韩岚
Owner ANHUI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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