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Traditional Chinese medicine preparation for treating phlegm-heat excessive accumulation type chronic cough

A traditional Chinese medicine preparation and technology for chronic cough, applied in the field of traditional Chinese medicine, can solve the problems of limiting the clinical efficacy of medicines and no medicines available, and achieve the effect of no toxic side effects, safe medicine and good effect

Inactive Publication Date: 2016-05-04
QINGDAO MUNICIPAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] As a symptom, western medicine summarizes chronic cough as a clinical manifestation of respiratory diseases. Although most diseases can be diagnosed, the clinical efficacy of drugs is limited due to the abuse of antibiotics and hormones. Therefore, in the face of ineffective treatment Cough symptoms, often in distress for which no medicine is available

Method used

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  • Traditional Chinese medicine preparation for treating phlegm-heat excessive accumulation type chronic cough
  • Traditional Chinese medicine preparation for treating phlegm-heat excessive accumulation type chronic cough

Examples

Experimental program
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Effect test

preparation example Construction

[0054] The present invention also provides the preparation method of above-mentioned Chinese medicine preparation, it comprises:

[0055] The first step is to weigh Sun-dried Ephedra, Raw Glycyrrhizae, Pinellia, Scutellaria, Morus alba, Japonica Rice, Ophiopogon japonicus, Fritillaria, Trichosanthes, Peucedanum, Houttuynia cordata, Tangerine Peel and Qingdai, and wash them separately. Clean, pulverize, mix together, add 5 to 10 times the mass of the mixture in ethanol with an alcohol concentration of 70% to 80%, soak for 1 to 2 hours, heat and extract twice, each time for 1 to 2 hours, and combine the extracts, 100-mesh filtration, and then ultrafiltration through an ultrafiltration column with a cut-off molecular weight of 5,000 to 10,000. The ultrafiltrate is concentrated under reduced pressure to an extract with a relative density of 1.30 to 1.36 at 60°C, and left to stand for later use;

[0056] In the second step, take the remaining raw materials by weight, wash and pulve...

Embodiment 1

[0060] Embodiment 1 oral liquid 1

[0061] Weigh 30g Sun-dried Ephedra, 20g Raw Glycyrrhiza, 20g Pinellia, 30g Scutellaria, 20g Cortex Mori, 20g Japonica Rice, 30g Ophiopogon japonicus, 20g Fritillaria, 20g Trichosanthes, 15g Peucedanum, 30g Houttuynia cordata, tangerine peel 15g and 10g of Qingdai, wash and pulverize respectively, mix together, add 2.2kg of ethanol with 80% alcohol concentration and soak for 2 hours, heat and extract twice, each time for 2 hours, combine the extracts, filter through 100 mesh , and then ultrafiltration through an ultrafiltration column with a cut-off molecular weight of 10,000, and the ultrafiltrate is concentrated under reduced pressure to an extract with a relative density of 1.36 at 60°C, and it is left to stand for later use. , 30g of raw gardenia, 15g of bellflower, 15g of perilla, 20g of Digupi, 15g of Tinglizi, 15g of reed rhizome, 15g of Poria cocos, 15g of Baiqian, 20g of broccoli, 35g of honeysuckle, washed and crushed respectively, ...

Embodiment 2

[0062] Embodiment 2 oral liquid 2

[0063] Weigh roasted ephedra 30g, raw licorice 15g, French pinellia 15g, scutellaria baicalensis 30g, mulberry bark 20g, japonica rice 20g, Ophiopogon japonicus 30g, Zhe Fritillaria 15g, Trichosanthes 15g, Peucedanum 10g, Houttuynia cordata 30g, tangerine peel 10g and 5g of Qingdai, wash and pulverize respectively, mix together, add 2kg of ethanol with alcohol concentration of 80% and soak for 2 hours, heat and extract twice, each time for 2 hours, combine the extracts, filter through 100 mesh, Then go through an ultrafiltration column with a cut-off molecular weight of 10,000, and concentrate the ultrafiltrate under reduced pressure to concentrate the extract with a relative density of 1.36 at 60°C, leave it for later use, weigh 10g of almonds, 25g of raw gypsum, 25g of Zhuru, 15g of Citrus aurantium, Raw Gardenia 25g, Campanulaceae 15g, Perilla 10g, Digupi 15g, Tinglizi 10g, Reed Rhizome 10g, Poria 15g, Baiqian 15g, Sunburn 15g, Honeysuckl...

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Abstract

The invention provides a traditional Chinese medicine preparation for treating a phlegm-heat excessive accumulation type chronic cough. The traditional Chinese medicine is prepared from rhizome of ephedra sinica, apricot kernels, raw gypsum, radix glycyrrhizae, caulis bambusae in taeniam, fruits of immature citron, rhizoma pinellinae praeparata, fructus gardenia, Scutellaria baicalensis, Platycodon grandiflorum, perillaseeds, the root bark of white mulberry, cortex lycii radicis, polished round-grained rice, semen lepidii, rhizoma phragmitis, tuber of dwarf lilyturf, thunberg fritillary bulb, poria cocos, trichosanthes kirilowii maxim, common hogfennel roots, cynanchum glaucescens, radix stemonae, cordate houttuynia, tangerine peels, honeysuckle and indigo naturalis. Under the guidance of the theory of traditional Chinese medicine, on the basis of a large amount of clinical observation, the pattern of syndrome, clinical performance, treatment prognosis and the like are comprehensively analyzed, prescription medication is achieved, the effects of cough relieving, asthma relieving and phlegm dispersing are achieved, and it proves that the traditional Chinese medicine preparation has the effect of treating the phlegm-heat excessive accumulation type chronic cough through animal experimental verification and traditional Chinese medicine safety evaluation.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine preparation for treating chronic cough of the syndrome of excess phlegm-heat. Background technique [0002] Chronic cough is considered in modern medicine as a reflex defensive action. When the human body coughs, it can clean up the secretions and foreign objects in the respiratory tract. But at the same time, coughing also has a negative side. For example, coughing can spread infection in the respiratory tract, severe coughing can lead to respiratory tract bleeding, and even induce spontaneous pneumothorax. Frequent coughing can seriously affect the patient's work, life and social activities. In recent years, scholars have continued to study the pathogenesis, diagnosis and treatment of cough. Using diagnostic methods such as X-ray examination, pulmonary function examination, allergen examination, and fiberoptic bronchoscopy, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61P11/14A61P11/10A61K33/06
CPCA61K33/06A61K9/0095A61K9/145A61K36/076A61K36/17A61K36/195A61K36/23A61K36/27A61K36/31A61K36/315A61K36/346A61K36/355A61K36/428A61K36/484A61K36/535A61K36/539A61K36/605A61K36/704A61K36/736A61K36/744A61K36/752A61K36/78A61K36/815A61K36/8888A61K36/8966A61K36/8968A61K36/899A61K36/904A61K2236/13A61K2236/15A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55A61K2300/00
Inventor 葛云洁李靖肖芝秀袁莉
Owner QINGDAO MUNICIPAL HOSPITAL
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