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Traditional Chinese medicine for treating cardiogenic cerebral embolism and preparation method of traditional Chinese medicine

A technology for cerebral embolism and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine for the treatment of cardiogenic cerebral embolism and its preparation, can solve problems such as failure to find emboli, unknown origin, etc., and achieves no toxic side effects and adverse reactions, cure rate and marked efficiency High, easy-to-use effects

Inactive Publication Date: 2016-05-04
冯雪华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] 3. Unknown source and part of cerebral embolism using modern means and methods, the source of embolism cannot be found even after careful inspection is called unknown source of embolus

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0050] When the dosage form of the Chinese medicine is a powder, its preparation method may further comprise the steps:

[0051] In the first step, Lvqing, plum kernels, selaginella, oak bark, ironwort, soft bark, bitter bamboo leaves and Scherichia chinensis are mixed according to the stated ratio, using 3-3% relative to the quality of the obtained mixture 5 times the alcohol concentration is 85% ~ 95% ethanol dissolved, heated and refluxed for 2 to 4 hours, extracted, filtered to obtain the first filtrate; the filter residue was again used with an alcohol concentration of 1 to 2 times the mass of the obtained mixture Dissolve 85%-95% ethanol, heat and reflux for 1-2 hours, extract, filter to obtain the second filtrate; combine the first filtrate and the second filtrate, recover the ethanol under reduced pressure and concentrate until the concentration of the liquid is 0.7- 0.9g crude drug / mL, eluted through a macroporous adsorption resin column with a volume of 5L, first elu...

Embodiment 1

[0061] Embodiment 1: the powder prepared by the present invention

[0062] Take 350g green green, 380g plum kernel, 120g selaginella, 180g oak bark, 320g ironwort, 280g soft bark, 160g bitter bamboo leaves, 100g Scherichia chinensis, 190g large calyx staghorn vine, 350g Xiatian cream, Jianwei Fenggen 210g, Dripping Blood Root 150g, Horse Bone 210g and Wild Horseshoe Grass 290g.

[0063] Its preparation method comprises the following steps:

[0064]In the first step, mix Lvqing, plum kernels, Selaginella, oak bark, ironwort, soft bark, bitter bamboo leaves and Scherichia chinensis according to the stated ratio, using 5 times the mass of the mixture obtained The alcohol concentration is 95% ethanol dissolving, heated to reflux for 3 hours and then extracted, filtered to obtain the first filtrate; the filter residue was dissolved again with 2 times the alcohol concentration of 95% ethanol relative to the quality of the mixture obtained, and heated to reflux for 2 After one hour...

Embodiment 2

[0067] Embodiment 2: the capsule prepared by the present invention

[0068] Take 320g green green, 360g plum kernel, 150g selaginella, 170g oak bark, 340g ironwort, 250g soft bark, 190g bitter bamboo leaves, 70g Scherichia chinensis, 230g large calyx staghorn vine, 320g Xiatian cream, Jianwei Fenggen 250g, Dripping Blood Root 120g, Horse Bone 230g and Wild Horseshoe Grass 270g.

[0069] Its preparation method comprises the following steps:

[0070] In the first step, mix the green green, plum kernel, selaginella, oak bark and ironwort according to the stated ratio, add 5 times the water relative to the mixture to extract the volatile oil, and clathrate the obtained volatile oil with β-cyclodextrin , the ratio of volatile oil to β-cyclodextrin is 1:5, stirred for 85 minutes at a temperature of 45°C to obtain a volatile oil clathrate, and set aside; in addition, the water extract is concentrated to a clear paste with a relative density of 1.17 at 60°C;

[0071] In the second s...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating cardiogenic cerebral embolism and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine comprises raw materials as follows: malachite, seeds of Japanese apricots, tamariskoid spikemoss herbs, sawtooth oak bark, herbs of bermudagrass, Daphne papyracea Wall., bitter bamboo leaves, Schefflera venulosa, Chonemorpha megacalyx Pierre, extract of beef, roots of longestapex beautyberry, wedelia urticaefolia, horse bones and herbs of rush-like bulrush. The traditional Chinese medicine has the benefits as follows: the traditional Chinese medicine is combined with a conventional western medicine method to treat cardiogenic cerebral embolism, is convenient to use and does not have toxic or side effects or cause poor reactions, the treatment effect is effectively improved, the cure rate and the effect rate are higher, and the preparation process is simple.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine engineering, in particular to a traditional Chinese medicine for treating cardiogenic cerebral embolism and a preparation method thereof. Background technique [0002] Cerebral embolism is also called embolic cerebral infarction. Refers to certain abnormal solid, liquid or gas embolic substances in the blood circulation of the human body, which enter the cerebral arteries or the carotid arteries supplying the brain with the blood flow, causing acute occlusion of the vascular lumen, causing local cerebral blood flow interruption, resulting in local cerebral arteries. Tissue ischemia, hypoxia, or even softening and necrosis lead to clinical manifestations of acute brain dysfunction. Cerebral embolism often occurs in the internal carotid artery system, and the vertebral-basilar artery system is relatively rare. [0003] According to the source of emboli, the etiology can be div...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P9/10A61K35/34A61K35/32A61K33/34
CPCA61K36/899A61K9/146A61K9/4866A61K33/34A61K35/32A61K35/34A61K36/11A61K36/185A61K36/24A61K36/25A61K36/28A61K36/736A61K36/83A61K36/85A61K36/89A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/55A61K2300/00
Inventor 冯雪华王金光
Owner 冯雪华
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