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Medicine composition for treating lung abscesses and application thereof

A composition and technology of lung abscess, applied in the field of medicine, can solve problems such as difficult treatment of lung abscess, increase of lung abscess, increase of drug-resistant strains, etc., achieve good inhibitory effect, reduce adverse reactions, and eliminate weak symptoms

Inactive Publication Date: 2016-04-20
汪芳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, due to the massive abuse of antibiotics such as cefoperazone sulbactam, the number of drug-resistant strains has increased, and the number of lung abscesses seems to increase, which brings difficulties to the treatment of lung abscesses.

Method used

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  • Medicine composition for treating lung abscesses and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Embodiment 1: the preparation of Chinese medicine capsule

[0013] Weigh 1.9kg of radish leaves, 2.0kg of agrimony, 1.2kg of fat sea, 1.2kg of raw land, 1.8kg of winter melon seeds, 0.9kg of Sophora japonica, 0.9kg of lilies, 1.2kg of three stamens, 0.9kg of holly leaves, and 0.5kg of lacquer , Tinglizi 0.8kg, Baiji 0.8kg and cinnamon 0.6kg, combined, add water equivalent to 15 times the total mass of medicinal materials, soak for about 1 hour, then decoct three times, decoct for about 1.5 hours for the first time, filter out the medicine Add 12 times the amount of water for the second time, decoct for about 1.2 hours, filter out the medicinal solution for later use; add 10 times the amount of water for the third time, decoct for about 1.2 hours, filter out the medicinal solution for later use; Combine the three decoctions, filter, and collect the filtrate; concentrate the filtrate to a thick paste, bake at low temperature, and crush it through a 100-mesh sieve to obtai...

Embodiment 2

[0014] Embodiment 2: The curative effect research of Chinese medicine treatment lung abscess

[0015] 78 patients with lung abscess, including 42 male patients and 36 female patients; aged 33 to 71 years, abscess location: 21 cases were located in the left upper lung, 19 cases were located in the left lower lung, 20 cases were located in the right upper lung, and 18 cases were located in the right lower lung ; Abscess diameter range: 4.5 ~ 13.8cm. All patients with lung abscess were divided into observation group (39 cases) and control group (39 cases). The general clinical data of the two groups of patients were compared and analyzed, and the difference was not statistically significant, which can be used for clinical comparison.

[0016] Patients in the control group were given 0.4 g of metronidazole and 2 g of cefoperazone-sulbactam, diluted to 100 mL of 0.09% normal saline, intravenously, once a day. Observation group patients were given metronidazole 0.4g, diluted into ...

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Abstract

The invention discloses a medicine composition for treating lung abscesses and application thereof. The medicine is prepared from radish leaves, herba agrimoniae, semen sterculiae lychnophorae, roots of rehmannia, seeds of Chinese waxgourd, sophora flowers, bulbus lilii, sonerila tenera royle, leaves of chinese ilex, sun euphorbia herbs, semen lepidii, rhizoma bletillae and cortex cinnamomi. The medicine composition has a good inhibitory effect on pathogenic microorganisms, can increase the effective rate of clinical treatment of lung abscesses through metronidazole and also lowers the occurrence rate of adverse reactions.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a pharmaceutical composition for treating lung abscess and its application. Background technique [0002] Lung abscess is a purulent lesion of lung tissue caused by a variety of pathogenic microorganisms invading the lung, and is a relatively common type of pulmonary suppurative infectious disease. In the early stage of the disease, lung abscess is often formed due to liquefaction and necrosis of the lungs caused by suppurative pneumonia. The clinical onset is usually rapid, and it is often manifested as chills, acute high fever, cough, and sputum. The sputum is large and purulent. , with one or more gas-filled fluid cavities on chest x-ray. People suffering from this disease can be caused by bacterial infection and bronchial blockage, which reduce the body's ability to resist germs and inhale germs. The disease is more common in young adults, and the incidence rate...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P11/00
CPCA61K36/31A61K9/1652A61K36/185A61K36/42A61K36/47A61K36/489A61K36/54A61K36/73A61K36/804A61K36/8967A61K36/898A61K36/899A61K2300/00
Inventor 汪芳徐敏李进英
Owner 汪芳
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