Box-type DNA sequencer with linear feeding CCD camera

Abstract

The invention relates to a box-type DNA sequencer with linear feeding CCD camera. The box-type DNA sequencer comprises a response recording subsystem, a reagent supply system and a control system, as well as a sequencer box body bearing all the systems, wherein the response recording subsystem and the reagent supply system are respectively arranged in a left side section and a right side section of the sequencer box body; the control system is arranged at the rear side of the response recording subsystem in the left side section of the box body; and a motion platform component comprises a motor, a lead screw guide rail component connected with an output shaft of the motor, a support seat supporting the lead screw guide rail component, a detection component and a camera support component. The box-type DNA sequencer is provided with the linear feeding CCD camera and the motion platform component, and feeding and withdrawing of the camera can be finished in the space of the box body structure to complete photographing, so that sampling of the sequencer is finished while the working space is saved.

Description

technical field [0001] The invention relates to the field of DNA sequencing, in particular to a box-type DNA sequencer with a linear feed CCD camera. Background technique [0002] In the field of DNA sequencing technology, the overall operation process is described as follows: After the DNA sample is crushed, the library building reagent is used to add adapters, single-strand capture, bind to microspheres, microemulsion PCR amplification, and emulsion breaking, and obtain the microspheres. For the DNA library, the library and the enzymes required for the sequencing reaction are placed on the sequencing chip with a micro-reaction pool by using the sample plate, and the sequencing chip and sequencing reagents are installed on the host computer, and the sequencing program is started by the control computer according to the number and position of the modules, which is automated The sequencing reaction is carried out, and the generated data is transmitted to the data analysis com...

AI Technical Summary

Problems solved by technology

[0003] In the actual process of DNA sequencing, a CCD camera is used to take pictures of the test process of the reaction chamber. The CCD camera needs to be fed and returned as required. It is required that the sequencer should have continuous and controllable control during the reagent supply and sequencing reaction process. characteristics, and the sequencing reaction and reagent supply equipment should have a stable and airtight operating environment; the existing DNA sequencing equipment is difficult to meet the above requirements

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