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Preparation method of atomized inhaling liquid used after cardiac surgery

An atomized inhalation and obtained technology, which is applied in the field of preparation of atomized inhalation liquid after extracardiac surgery, can solve the problems of bronchial secretion retention, insufficient lung ventilation, pulmonary atelectasis, etc., and can inhibit skin allergic antibodies and reduce irritation. Effects of cough, mild central nervous system stimuli

Inactive Publication Date: 2016-02-03
庞大斌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, if antitussive drugs are used, the bronchial secretions will be retained due to the suppression of the cough reflex, resulting in hypoventilation of the lungs, and even atelectasis of the lungs, leading to lung infection

Method used

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  • Preparation method of atomized inhaling liquid used after cardiac surgery

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1, the weight ratio of raw materials: papaya 20g, rutabaga 12g, Yaluochun 12g, dendrobium 15g, Daozhalong 15g, wintergreen 15g, camphor 15g, saponin 15g, chicken head rice 15g, linseed 12g, ghost grass 2g, stone flower 20g.

[0033] The preparation method of Example 1 is: mix papaya, wintergreen, rutabaga, chicken head rice, yarrow, dendrobium, daozhalong, camphor, saponin, ghost grass, flaxseed, stone flower, add water and decoct , take the filtrate after 30 minutes, add water to the dregs and continue to decoct for 20 minutes, then take the filtrate, combine the two filtrates, and then filter with two layers of gauze. Add 95% ethanol to make the ethanol concentration of the solution reach 75%, keep it airtight for 48 hours, filter, remove ethanol from the filtrate, and use G 4 Filter through a vertically fused glass funnel until clear, sterilize at 100°C for 30 minutes, and store.

Embodiment 2

[0034] Example 2, raw material drug weight ratio: 10 parts of papaya, 3 parts of rutabaga, 3 parts of Yaluochun, 12 parts of dendrobium, 12 parts of Daozhalong, 12 parts of wintergreen, 12 parts of camphor, 12 parts of saponins , 12 parts of chicken head rice, 3 parts of flaxseed, 1 part of ghost grass, and 10 parts of stone flower.

Embodiment 3

[0035] Example 3, the weight ratio of raw materials: 20 parts of papaya, 12 parts of rutabaga, 12 parts of Yaluochun, 15 parts of dendrobium, 15 parts of Daozhalong, 15 parts of wintergreen, 15 parts of camphor, 15 parts of saponins , 15 servings of chicken head rice, 12 servings of flax seeds, 2 servings of ghost grass, and 20 servings of stone flowers.

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Abstract

The invention discloses a preparation method of an atomized inhaling liquid used after cardiac surgery. The atomized inhaling liquid is used to intervene cough after cardiac surgery. The preparation method is characterized by comprising the following steps: (1) extracting volatile oil from pawpaw, prinsepia uniflora, cipadessa baccifera, dendrobium, cinnamomum camphora, solanum lyratum, and coarse powder of flax seed to obtain mixed volatile oil and dregs, and saving the mixed volatile oil and dregs for later use; (2) evenly mixing rubus wilsonii, pyrola calliantha, salix wallichiana, gorgon fruit, parmelia saxatilis and dregs obtained in the step (1), carrying out water extraction and alcohol precipitation, filtering to remove alcohol, performing ultrafiltration by using a microporous membrane, and condensing and drying the filtrate to obtain a primary material; (3) spraying the volatile oil obtained in the step (1) into the primary material obtained in the step (2), evenly mixing, grinding, sieving the powder by a 100-mesh sieve, and finally sterilizing the powder. The clinical experiment results show that the provided atomized inhaling liquid can well treat cough after cardiac surgery, is very safe, and thus is worthy to promote and use in clinic.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a preparation method of atomized inhalation liquid after cardiac surgery. Background technique [0002] Thoracotomy in cardiothoracic surgery is traumatic and takes a long time. During the operation, the lung lobes are often squeezed to expand the field of view, and the stimuli of tracheal intubation, etc., reflexively cause increased respiratory secretions, mucus secretion disorders, and clearance obstacles. Postoperative patients are weak in constitution, unable to cough up sputum and sticky sputum, resulting in sputum retention, reduced effective breathing area, resulting in decreased respiratory function, resulting in pulmonary complications and affecting prognosis. [0003] In order to solve the above-mentioned problems, some clinicians currently advocate the use of oxygen-driven atomized inhalation after surgery. The oxygen-driven atomized inhalation uses high-sp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61K9/12A61K9/72A61P11/14A61P11/00
Inventor 庞大斌
Owner 庞大斌
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