Biodegradable material

A biodegradable, biological technology, applied in drug delivery, catheters, medical science, etc., can solve the problems of insufficient effect and insufficient inhibition of inflammation, and achieve the effect of inhibiting pH changes

Inactive Publication Date: 2016-01-20
SOFSERA CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0010] However, the stent described in Patent Document 2 may not necessarily have sufficient mechanical strength, and may not sufficiently neutralize the acidic components of polyester decomposition products, so that inflammation in the living body may not be sufficiently suppressed.

Method used

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  • Biodegradable material
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Embodiment Construction

[0022] The biodegradable material of this embodiment is a material in which calcium phosphate of a specific particle size is blended into a biodegradable polyester base material. Hereinafter, the constituent components, composition, physical properties, production method, and use of the biodegradable material of the present embodiment will be described in detail. In addition, the present embodiment is an example, and other forms or various modified examples that can be conceived by those skilled in the art within the scope of the invention described in the claims also belong to the technical scope of the present invention.

[0023] "Constituents of biodegradable materials"

[0024] The constituent components of the biodegradable material of this embodiment will be described. The biodegradable material of the present embodiment is a material in which biodegradable polyester is used as a base material, and hydroxyapatite particles are mixed into the base material. Hereinafter,...

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Abstract

To provide a biodegradable material that has sufficient mechanical strength, considering in vivo use also, and that can suppress pH changes caused by an acidic degradation product. Provided is a biodegradable material the base material of which is polyester, and that is characterized by comprising calcium phosphate particles having an average particle diameter of 10 to 1,000 nm.

Description

technical field [0001] The invention relates to a biodegradable material. Background technique [0002] Biomaterials using biodegradable polymers as base materials are being studied as ideal members for use in living bodies, such as scaffolds and bone fixation members. [0003] For example, Patent Document 1 describes a stent for blood vessels made of polylactic acid (PLLA) with the optical purity of the L-form in a predetermined range and the weight average molecular weight in a predetermined range. After being implanted in the living body, it is decomposed and disappears in the living body. [0004] However, when such a biodegradable polyester is applied to a living body, an acidic decomposition product is produced when the polyester is decomposed in the body, which may cause inflammation, which is regarded as a problem. [0005] In response to this problem, in Patent Document 2, a scaffold is described, which not only contains polylactic acid as a biodegradable polymer,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08L67/00A61L29/00A61L31/00C08K3/32C08L101/16
CPCC08K3/32C08L101/16A61L31/148C08K2003/325C08K2201/018A61L31/127C08L67/04A61L31/06A61L2400/18
Inventor 小粥康充河边卡尔和重山田健二
Owner SOFSERA CORP
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