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Antibacterial polyvinyl chloride material, preparation method and application thereof

A technology of polyvinyl chloride and polyvinyl chloride resin, which can be used in surgery, medical science, etc., and can solve problems such as increased resistance

Active Publication Date: 2016-01-06
BEIJING UNIV OF CHEM TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since the size of macromolecules is much larger than that of small organic molecules, the resistance to crossing the cell wall and cell membrane will also be greatly increased, which may make it difficult to contact the target site inside the bacterial cell

Method used

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  • Antibacterial polyvinyl chloride material, preparation method and application thereof
  • Antibacterial polyvinyl chloride material, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0114] With 100 parts of PVC resin (weight-average molecular weight is 150,000, and M w / M n3.5, purchased from Formosa Plastics Industry (Ningbo) Co., Ltd., model is SG-4), 3 parts of nanometer silver-loaded titanium dioxide (average particle diameter is 30nm, silver content is 2% by weight, purchased from Xuancheng Jingrui New Material Co., Ltd. company, model VK-T07), 4 parts of polyquaternium-1 (purchased from Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd., pharmaceutical grade, relative molecular mass is 810.21), 4 parts of Chimassorb944 light stabilizer, 2 parts of calcium-zinc compound Stabilizer, 5 parts of epoxidized soybean oil, 0.4 part of tris(nonylphenyl phosphite) and 0.3 part of benzyl silicone oil are first added to the high-speed mixer, and the stirring is started at a temperature of 45°C, the blade speed is 950rpm, and the mixture is mixed for 5 minutes , and then add 45 parts of environmentally friendly and non-toxic composite plasticizers (including 2...

Embodiment 2

[0126] Repeat Example 1, the difference is: the nano-silver-loaded titanium dioxide used in Example 1 is replaced by nano-titanium dioxide (average particle size is 80nm).

[0127] The test results are shown in Table 1 and Table 2.

Embodiment 3

[0132] Repeat Example 1, the difference is: 4 parts of Chimassorb944 light stabilizer are replaced by 2 parts of CyasorbUV-3346 light stabilizer and 2 parts of Tinuvin622 light stabilizer.

[0133] The test results are shown in Table 1 and Table 2.

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Abstract

The invention relates to an antibacterial polyvinyl chloride material. The antibacterial polyvinyl chloride material comprises polyvinyl chloride resin, wherein the material comprises the following compounds in every 100 parts of polyvinyl chloride resin as basic resin by weight: (A) 2-10 parts of a combined antibacterial agent by weight, the combined antibacterial agent comprising at least one of an antibacterial agent A selected from titanium dioxide and silver-supported nano titanium dioxide and an antibacterial agent B selected from a polyquaternium antibacterial, wherein the weight ratio of the antibacterial agent A to the antibacterial agent B is 1: 3 to 4: 3; (B) a plasticizer; and (C) an optional stabilizer. The antibacterial polyvinyl chloride material comprises the specific combined antibacterial agent, so that the polyvinyl chloride material has strengthened antibacterial ability and has a good mechanical property. The invention also relates to preparation and application of the polyvinyl chloride material, and the material can serve as a medical polymer material, particularly a medical catheter material, particularly a tracheal catheter material.

Description

technical field [0001] The invention belongs to the field of biomedical polymer materials, and in particular relates to an antibacterial polyvinyl chloride material and its preparation method and application. The polymer material can be used as a medical polymer material, especially as a trachea tube material. Background technique [0002] The application of biomedical materials has greatly promoted the rapid development of medical diagnosis and treatment technology. It is a kind of material that is biocompatible with animals and has special properties or functions that can be used for the repair and replacement of animal organs and tissues, diagnosis and treatment of diseases. . Among them, endotracheal intubation is an important measure to establish an artificial airway, ensure the smoothness of the airway, and the body's oxygen demand and carbon dioxide excretion. It is an indispensable basic technology for modern anesthesiology and modern emergency medicine. The standar...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08L27/06C08K13/06C08K9/12C08K3/08C08K3/22C08K5/12C08K5/11C08K5/1515C08K5/526A61L31/04A61L31/16
Inventor 丁雪佳欧远辉张龙刘燕琴王国胜范义峰
Owner BEIJING UNIV OF CHEM TECH
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