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Application of Babaodan in preparation of medicine for treating primary sclerosing cholangitis

A primary, sclerosing technology, applied in drug combination, medical raw materials from mollusks, medical raw materials from mammals, etc., can solve the problem of unproven survival benefit, harmful advanced disease, unclear effect of liver disease, etc. problems, to achieve effective and efficient treatment

Active Publication Date: 2019-05-03
XIAMEN TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Thus, the role of UDCA in reducing PSC-associated liver disease progression remains unclear, and high doses of UDCA may be detrimental for advanced disease
[0007] (2) Immunosuppressants and other agents: Glucocorticoids and other immunosuppressants have not been shown to improve disease activity or outcome in PSC
[0008] In summary, the obtained data show that UDCA (15-20 mg / d) improves serological test indicators and prognostic surrogate indicators, but the benefit on survival rate has not been proved. The limited data do not make a special recommendation for UDCA as a general treatment drug for PSC permission of

Method used

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  • Application of Babaodan in preparation of medicine for treating primary sclerosing cholangitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Take commercially available Babaodan capsules (Guoyao Zhunzi Z10940006, produced by Xiamen Traditional Chinese Medicine Factory Co., Ltd.), each capsule contains 0.25-0.3g of Babaodan, and it is used to prepare the medicine for treating primary sclerosing cholangitis. When patients take it, 2-3 times a day, 2 capsules each time.

Embodiment 2

[0026] Take commercially available Babaodan lozenges (Guoyao Zhunzi Z10940005, produced by Xiamen Traditional Chinese Medicine Factory Co., Ltd.) and pulverize them, add conventional excipients to make tablets, each tablet contains 0.5g of Babaodan, and is used to prepare and treat primary sclerosis Among the drugs for chronic cholangitis, when patients take it, 3 times a day, 1 to 2 tablets each time.

Embodiment 3

[0028] Take commercially available Babaodan lozenges (Z10940005, produced by Xiamen Traditional Chinese Medicine Factory Co., Ltd.) and pulverize them, add conventional excipients to make granules, and each bag of granules contains 0.6g of Babaodan, which is used to prepare and treat primary sclerosis Among the drugs for chronic cholangitis, when the patient takes it, 3 times a day, 1 bag each time.

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Abstract

The invention discloses eight-jewel elixir and novel application of preparations of the eight-jewel elixir, and particularly relates to application of eight-jewel elixir to preparing medicine for treating primary sclerosing cholangitis. The application has the advantages that the eight-jewel elixir and preparations of the eight-jewel elixir can be applied to wide fields, and a novel traditional Chinese medicine treatment method is developed for treating the primary sclerosing cholangitis.

Description

technical field [0001] The invention relates to a new application of Babaodan, in particular to the application of Babaodan and its preparation in the preparation of medicines for treating primary sclerosing cholangitis. Background technique [0002] The main ingredients of Babao Dan are bezoar, snake gall, antelope horn, pearl, Panax notoginseng, musk, etc. It is currently used for fever, jaundice, yellow and red urine, nausea and vomiting, anorexia, hypochondriac pain and abdominal distension, and tongue coating caused by accumulation of damp heat. Yellow greasy or thick greasy dry white, or hot and tingling urethra caused by hot and humid betting, lower abdominal pain, and infectious viral hepatitis, acute cholecystitis, acute urinary tract infection, etc. [0003] Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by progressive inflammation, fibrosis, and multiple strictures of the bile ducts. The pathogenesis of PSC has not been ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/258A61P1/16A61K35/32A61K35/413A61K35/55A61K35/618A61K35/583
Inventor 墙世发叶红英詹志学林宝华
Owner XIAMEN TRADITIONAL CHINESE MEDICINE
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