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Medical application of genistein chromium complex to treatment of diabetes

A technology of lignochrome and complexes, applied in the field of medicine and pharmacy, can solve problems such as no application report of lignochrome complexes, and achieve the effects of reducing toxicity, improving hypoglycemic effect, and improving hypoglycemic activity.

Active Publication Date: 2015-12-02
BEIJING UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] There is no report on the application of the genistein chromium complex in the prevention and treatment of diabetes

Method used

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  • Medical application of genistein chromium complex to treatment of diabetes
  • Medical application of genistein chromium complex to treatment of diabetes
  • Medical application of genistein chromium complex to treatment of diabetes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] With genistein chromium complex as the active ingredient, it can be made into any medicine for the treatment of type 2 diabetes.

[0074] Take 300g of genistein chromium complex, add appropriate amount of starch, mix well, dry below 60℃, and encapsulate 1000 capsules to obtain the capsule preparation of this product. This project meets the relevant requirements of the capsule project of the 2000 edition of the Pharmacopoeia of the People's Republic of China.

Embodiment 2

[0076] Take 500g of genistein chromium complex, add appropriate amount of starch and lubricant, mix well, dry below 60°C, and press to obtain 1000 tablets. This project meets the relevant requirements of the tablet project of the 2000 edition of the Chinese Pharmacopoeia.

Embodiment 3

[0078] Take 800g of the genistein chromium complex, add an appropriate amount of starch, mix well, dry below 60°C, and granulate to obtain 1000 bags of granules. This project complies with the relevant requirements of the 2000 edition of the People’s Republic of China Pharmacopoeia.

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Abstract

The invention provides medical application of a genistein chromium complex to treatment of diabetes. Results of the animal growth condition research, fasting blood-glucose value determination, glucose tolerance test, insulin tolerance test show that the genistein chromium complex has an excellent hypoglycemic effect, and can be used for preparing drugs for treating diabetes II; by combing the hypoglycemic advantage of chromium, the hypoglycemic activity of genistein is improved obviously and toxicity of inorganic chromium can be reduced.

Description

technical field [0001] The invention discloses the medical application of a genistein chromium complex in treating diabetes, relates to a compound used for treating diabetes, and belongs to the technical field of medicine and pharmacy. Background technique [0002] Genistein is a flavonoid compound with various biological activities, chemically named as 5,7,4'-trihydroxyisoflavone, widely found in soybeans, clover, gorse, acacia, and sophora Among traditional medicinal plants, it has high medicinal value. [0003] Molecular formula of genistein chromium complex: [C 15 h 9 o 5 ] 3 Cr·2H 2 O; molecular weight: 895.5; named: genistein chromium complex; structural formula: [0004] [0005] There is no report on the application of the genistein chromium complex in the prevention and treatment of diabetes. Contents of the invention [0006] The invention provides the medical application of the genistein chromium complex in treating diabetes, which can obviously improv...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/555A61P3/10
Inventor 徐暾海李朋收刘铜华徐雅娟解生旭张曼祺
Owner BEIJING UNIV OF CHINESE MEDICINE
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