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Extract of Chinese herbal medicine and application of extract

An extract and traditional Chinese medicine technology, applied in the field of Bacopa monnieri extract, to achieve the effect of reducing content, increasing reserves, and improving exercise endurance

Inactive Publication Date: 2015-11-18
SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no literature report that Bacopa monnieri or its extracts have anti-fatigue effect

Method used

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  • Extract of Chinese herbal medicine and application of extract
  • Extract of Chinese herbal medicine and application of extract
  • Extract of Chinese herbal medicine and application of extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] The preparation of embodiment 1 Bacopa monnieri extract

[0019] 500g of dried Bacopa monnieri herb and 75% ethanol aqueous solution were subjected to reflux extraction twice at 75°C, each time for 1.5h, the ratio of solid to liquid was 1:12 and 1:10 respectively, combined and filtered twice, 50 ℃ concentrated into a thick paste, freeze-dried, crushed into fine powder, and passed through a 100-mesh sieve to obtain dry powder of Bacopa monnieri extract.

Embodiment 2

[0020] Example 2 Experimental Research on Anti-fatigue of Mice by Bacopa monnieri Extract

[0021] 1. Weight-bearing swimming test

[0022] 32 male ICR mice were selected, and after being adapted to feeding for 1 week, the mice were divided into 4 groups according to their body weight, with 8 mice in each group, which were the low, medium and high dose groups of Bacopa monnieri extract and the blank group. Control group (give the same volume of distilled water). Oral administration, once a day, continuous administration for 30 days. 40 minutes after the last administration, the mice with 5% body weight lead skin on the base of the tail were placed in the swimming box to swim. The water depth is 50cm, and the water temperature is 25°C±1°C. The time from the start of swimming to death of the mice was recorded, that is, the weight-bearing swimming time of the mice.

[0023] Dosage selection: high dose 5.0g / kg, medium dose 2.5g / kg, low dose 1.2g / kg.

[0024] See Table 1 for t...

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Abstract

The invention relates to an anti-fatigue ethanol extract of floriferous bacopa monnieri, a method for preparing the anti-fatigue ethanol extract and application thereof. The anti-fatigue ethanol extract, the method and the application have the advantages that anti-fatigue effects of the floriferous bacopa monnieri which is traditional Chinese medicine are observed via loaded-swimming fatigue models of mice, as proved by results, the loaded-swimming time of the mice can be obviously prolonged by the extract, the contents of blood lactic acid and serum urea nitrogen in the bodies of the mice can be reduced after the mice exercise, reserved hepatic glycogen further can be increased, and the exercise tolerance can be improved; the anti-fatigue effects can be realized by the extract of the floriferous bacopa monnieri, the fatigue degrees of human bodies can be obviously relieved by the extract, and the extract can be used for producing and processing food or healthcare products.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to an extract of Bacopa monniera with anti-fatigue effect and its application. Background technique [0002] With the progress of society and the rapid development of science and technology, the pace of people's life and work is also accelerating, and the mental pressure and psychological burden are increasing. More and more people feel tired in life and work. Fatigue is a kind of subjective discomfort and a sub-health state, which seriously affects the quality of life. Nearly 20% of adult males and 25% of females are reported to have this disorder. Anti-fatigue is to relieve the discomfort of fatigue through some methods. [0003] According to traditional Chinese medicine, fatigue is mainly caused by abnormal functions of the spleen, liver, and kidneys due to various reasons, and the heart and lungs involving qi, blood, and yin and yang imbalance. Modern med...

Claims

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Application Information

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IPC IPC(8): A61K36/80A23L1/30A61P39/00
CPCA23V2002/00A61K9/19A61K36/80A61K2236/333A61K2236/39A61K2236/51A23V2200/30A23V2250/21
Inventor 高越韩婷董睿方蔡林姚小军章海荣
Owner SECOND MILITARY MEDICAL UNIV OF THE PEOPLES LIBERATION ARMY
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