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Toothpaste with hemostasis and gum protection functions and preparation method of toothpaste

A toothpaste, efficacy technology, applied in dentistry, blood diseases, oral care, etc., can solve the problem of not finding Panax notoginseng extract toothpaste and so on

Inactive Publication Date: 2015-11-18
昆明牙膏有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In addition, in order to improve the hemostatic effect of toothpaste, no research has been found on the combination of Panax notoginseng extract and tranexamic acid in toothpaste

Method used

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  • Toothpaste with hemostasis and gum protection functions and preparation method of toothpaste
  • Toothpaste with hemostasis and gum protection functions and preparation method of toothpaste
  • Toothpaste with hemostasis and gum protection functions and preparation method of toothpaste

Examples

Experimental program
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preparation example Construction

[0028] In this embodiment, the preparation method includes: mixing Panax notoginseng saponins, friction agent, wetting agent, adhesive, foaming agent and water according to the weight percentage, stirring, grinding and vacuum degassing to obtain Toothpaste paste, wherein the stirring, grinding and vacuum degassing are all conventional preparation methods in the field. In this embodiment, it is selected to stir and grind in a three-in-one vacuum paste making machine for 25-40 minutes, and simultaneously play a role in vacuum degassing. The role of gas.

[0029] In this embodiment, the raw material may also include 0.05-0.5% by weight of tranexamic acid. Combined use of notoginseng extract and tranexamic acid further enhances the hemostatic effect of the toothpaste. The mixing in the preparation method also includes adding tranexamic acid.

[0030] In this example, too high content of notoginseng extract and tranexamic acid will affect the stability of the final paste, too low...

Embodiment 1

[0036] This embodiment provides a preparation method of a toothpaste with the effect of hemostatic and gingival protection, its raw materials include: calcium carbonate 55%, sorbitol 15%, carboxymethyl cellulose sodium 0.8%, carrageenan 0.5%, ten Dialkyl sodium sulfate 2%, essence 0.8%, saccharin 3%, Panax notoginseng extract 0.07%, and the rest is deionized water.

[0037] Preparation:

[0038]Mix Panax notoginseng saponins, friction agent, wetting agent, adhesive, foaming agent and deionized water, send it into a three-in-one vacuum paste making machine, and stir and grind for 25 to 40 times at a speed of 1000r / min. Minutes, vacuum degassing, after adding the essence, stir and grind for a second time at a speed of 1000r / min for 10-25 minutes to mix evenly, to obtain a toothpaste paste, which is filled and packaged through aseptic.

Embodiment 2

[0040] This embodiment provides a kind of preparation method of the toothpaste with hemostatic and gingival protection effect, its raw material comprises by weight percentage: calcium hydrogen phosphate 45%, glycerol 10%, propylene glycol 15%, xanthan gum 1%, guar gum 0.5% , sodium lauryl sulfate 2.5%, notoginseng extract 0.1%, and the rest is deionized water.

[0041] Preparation:

[0042] Put the Panax notoginseng extract, wetting agent and saccharin into deionized water and stir until the saccharin dissolves, mix with friction agent, adhesive, and card dealer, and send it to a three-in-one vacuum paste making machine at a speed of 1000r / Next, stir and grind for 25 to 40 minutes, vacuum degassing, and obtain toothpaste paste, which is aseptically filled and packaged.

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Abstract

The invention provides toothpaste with hemostasis and gum protection functions and a preparation method of the toothpaste. The toothpaste comprises, by weight, 0.03-1.0% of panax notoginseng extract, 30-55% of abrasives, 15-30% of wetting agents, 0.6-1.5% of adhesives, 2-2.7% of foaming agents and water. The preparation method includes the steps of mixing panax notoginseng saponins, tranexamic acid, the abrasives, the wetting agents, the adhesives and the water according to the weight percentage, conducting stirring and grinding for 25-40 minutes, conducting vacuum degassing, and obtaining a toothpaste body. By means of the combined application of the panax notoginseng extract and tranexamic acid, the toothpaste can have the enhanced hemostasis and gum protection functions.

Description

technical field [0001] The invention relates to an oral health product, especially a toothpaste with the effect of hemostasis and gum protection and a preparation method thereof. Background technique [0002] Panax notoginseng F.H.chen is a plant of the Araliaceae ginseng genus, which has hemostatic, anti-inflammatory, analgesic and other effects, and is widely used in the prevention and treatment of various cardiovascular and cerebrovascular diseases. Panax notoginseng contains a variety of chemical components. Among them, the total saponin content of Panax notoginseng accounts for about 12% of the tuber root, which is the main active ingredient of Panax notoginseng. More than 20 A monomeric saponin, including ginsenoside Rg 1 , Rg 2 , Rb 1 , Rb 2 , Rb 3 , Rc, Rd, Re, Rh, F 2 , notoginsenoside R 1 , R 2 , R 3 , R 6 , Fa, Fc, Fe, R 4 Wait. [0003] Notoginseng saponins are soluble in water and ethanol, and generally higher concentrations of ethanol are used to ex...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61K8/44A61Q11/00A61P1/02A61P7/04
Inventor 罗宏芳李崇云李全
Owner 昆明牙膏有限责任公司
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