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Medicine for treating chronic cardiac failures and preparation method of medicine

A technology for chronic heart failure and a manufacturing method, applied in the field of medicine, can solve the problems of decreased efficacy, increased tolerance, and side effects of drugs

Inactive Publication Date: 2015-11-04
GUIYANG COLLEGE OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] With the development and progress of medicine, there are many drugs for the treatment of heart failure on the market, but most of the drugs have side effects and drug resistance. Patients with chronic heart failure live with the disease for a long time and need to take medicine for a long time. If they take it for a long time, the efficacy of the medicine will decrease , increased tolerance

Method used

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  • Medicine for treating chronic cardiac failures and preparation method of medicine
  • Medicine for treating chronic cardiac failures and preparation method of medicine
  • Medicine for treating chronic cardiac failures and preparation method of medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] Recipe: Astragalus 480g, red ginseng 145g, salvia miltiorrhiza 242g, (made) Fupian 242g, motherwort 484g, safflower 145g, Polygonatum 161g and (burned) licorice 97g.

[0055] Process: Take the above-mentioned medicine, add 10 times the amount of water to decoct 3 times, each time for 1.5h, filter, combine the decoction liquid, concentrate into an extract with a relative density of 1.15-1.20 at 50-60°C, extract and extract 20% starch and 20% dextrin powder are mixed and granulated, and dried to obtain granules.

[0056] Specifications: 10g / bag.

[0057] Usage and dosage: 2 times a day, 10-20g each time, orally.

Embodiment 2

[0059] Recipe: Astragalus 560g, red ginseng 200g, salvia miltiorrhiza 300g, (made) Fupian 300g, motherwort 550g, Polygonatum 220g and (burned) licorice 150g.

[0060] Process: Take the above-mentioned medicine, reflux extract with 6 times the amount of 70% ethanol for 2 times, each time for 1 hour, filter the extract, recover the ethanol from the filtrate and concentrate it into an extract with a relative density of 1.20-1.25 at 50-60 °C, and another Get 30% starch and 0.7% magnesium stearate in the extract and mix with the extract, granulate with 60% ethanol, dry, pulverize, and fill capsules to obtain capsules.

[0061] Specification: 0.3g / grain.

[0062] Usage and dosage: take orally, 2 to 3 times a day, 3 capsules each time.

Embodiment 3

[0064] Recipe: Astragalus 400g, Red Ginseng 100g, Salvia miltiorrhiza 180g, (made) Fupian 180g, Motherwort 410g, Polygonatum 100g and (roasted) licorice 50g.

[0065] Process: Take the above medicine, add 10 times the amount of water to decoct 3 times, each time for 1.5h, filter, combine the decoction liquid, concentrate it into an extract with a relative density of 1.15-1.20 at 50-60°C, mix the extract with the above Mix the powder and extract with 20% starch, compress into tablets, and coat with film to obtain tablets.

[0066] Specification: 0.3g / piece.

[0067]Dosage: Take orally, 2-3 times a day, 3 tablets each time.

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Abstract

The invention discloses medicine for treating chronic cardiac failures and a preparation method of the medicine. The medicine is mainly prepared by radix astragali, red ginseng, salviae miltiorrhizae, prepared common monkshood daughter root, motherwort, radix polygonati officinalis, prepared liquorice and excipient. The medicine has effects of warming yang and benefiting qi and promoting blood circulation and diuresis, and is applicable to various chronic cardiac failures, capable of assisting the treatment of diseases such as acute cardiac failure, good in curative effect, free of medicine resistance and free of side effects.

Description

technical field [0001] The invention relates to a medicine for treating chronic heart failure and a preparation method thereof, belonging to the technical field of medicines. technical background [0002] Heart failure belongs to the categories of "asthma syndrome", "chest pain" and "palpitation" in traditional Chinese medicine. "Su Wen Bi Lun" says: "Heart pain suffers from blockage of the pulse, irritability causes the heart to swell, and the breath is violent and panting. "Wheezing, palpitation, fatigue, shortness of breath, especially concomitant movements, are manifestations of qi deficiency; chest tightness, chest pain, and dark purple tongue are signs of internal resistance from blood stasis; and these patients have a long course of disease, and "prolonged illness must be empty." , "Prolonged illness enters the collaterals", so its main pathogenesis is Qi deficiency and Yang deficiency with blood stasis, Qi deficiency and Yang deficiency are the foundation, and blood ...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P9/04
Inventor 张永萍孙刚徐剑曾真周琦王丹
Owner GUIYANG COLLEGE OF TRADITIONAL CHINESE MEDICINE
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