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Lysozyme oral care liquid and preparation method thereof

A technology of oral care and lysozyme, which is applied in the directions of oral care, antibacterial drugs, and pharmaceutical formulations, can solve problems affecting the taste of products, high alcohol content, fluorosis, etc., and improve oral health problems. The production and preparation methods are simple, Good effect on gingivitis

Active Publication Date: 2018-06-19
HUBEI SHENDI AGRI SCI & TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Common oral care solutions are oral sprays and mouthwash products. The oral care solutions sold on the market usually use antibiotics, bacteriostats, etc., which can easily cause side effects such as bacterial resistance or oral discomfort, such as: Chinese patent CN101829027 B Both fluoride and Chinese patent CN 101999990 B use fluoride as a bacteriostatic agent, but now many products including toothpaste contain fluoride, and long-term use can easily cause fluorine to exceed the standard. Studies have shown that excessive use of fluoride can cause fluorosis, causing A series of diseases, especially pregnant women and children under the age of 7 are not recommended to use fluoride products
[0006] Simultaneously, most of the oral care solutions sold on the market contain alcohol, which can stimulate the oral mucosa, making it inconvenient for patients with oral diseases to use, and also bringing inconvenience to drivers and alcohol allergies, such as: Chinese patent CN 101249056 B, although Luo Han Guo is added Active ingredients such as extracts and vitamin B12, but due to the solubility and stability of the formula, its alcohol content is as high as 20%
[0007] In addition, there are many oral sprays and mouthwash products of Chinese herbal medicines on the market, but Chinese herbal medicines often taste bitter and have a strong color, which greatly affects the taste and appearance of the products, such as: Chinese patent CN 101627965 B, which uses magnolia 1. At least two of propolis are active ingredients, both of which are bitter ingredients, which seriously affect the taste of the product

Method used

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  • Lysozyme oral care liquid and preparation method thereof
  • Lysozyme oral care liquid and preparation method thereof
  • Lysozyme oral care liquid and preparation method thereof

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Embodiment Construction

[0033] Embodiments of the present invention are described in detail below, but are not limited to the following embodiments:

[0034] A lysozyme oral care and health care liquid is provided, which is prepared according to the weight percentage of each component disclosed in the above-mentioned technical scheme and according to its preparation steps; the description will not be repeated.

[0035] Below, the screening and the source of each component of the present invention are further described; To prove its embodiment:

[0036] (1) Optimum dosage of active ingredient lysozyme

[0037] The optimal dosage of lysozyme was determined by the zone of inhibition method. Use the agar diffusion method to incubate the sterilized TSA medium in the air for 24 hours, take 0.2mL of the isolated and identified Staphylococcus aureus (Candida albicans) suspension on the plate, spread it evenly with a sterile glass handle, and apply After cloth, the plate shall be subject to no visible water...

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PUM

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Abstract

Lysozyme oral care and health care solution and preparation method thereof, comprising 0.01-10% lysozyme, 0.01-10% tea polyphenol, 0.001-0.1ppm vitamin B12, 0.1-10% cooling agent, 1-20% sweetener, Solvent 0.1‑6%, freshener 0.01‑0.6%, purified water 98.77%‑43.4%; select 0.01‑10% lysozyme, 0.01‑10% tea polyphenol, 1‑20% sweetener to dissolve in sequence In a stainless steel container, stir gently, mix well, and prepare liquid A; choose 0.1-10% cooling agent and 0.01-0.6% fragrance agent to dissolve in 0.1-6% solubilizer in sequence, gently Stir, mix well and prepare liquid B; slowly pour liquid B into liquid A, stir gently, and add 0.001‑0.1ppm of vitamin B12 and mix well; filter, pack and fill the uniformly mixed material It is ready; the lysozyme oral care and health care solution of the present invention has remarkable effects, and the main functional components are all natural extracts, and does not contain alcohol, and has a mild taste. oral mucosa.

Description

technical field [0001] The invention relates to the technical field of oral health products for killing harmful bacteria in the oral cavity and preventing oral problems, in particular to lysozyme oral care health care liquid and a preparation method thereof. Background technique [0002] The oral cavity is an important part of the digestive and respiratory systems of the human body. With the aggravation of air pollution and environmental deterioration, oral diseases are showing an obvious upward trend. Common oral diseases include oral ulcers, dental caries, periodontitis, gingivitis, etc. The important causes of oral diseases are incomplete oral cleaning and food residues remaining in the oral cavity. [0003] In daily life, people are used to brushing their teeth once in the morning and evening to clean the mouth, but it is difficult to ensure that the residues in the mouth are completely removed by brushing teeth. For example, it is difficult for children to clean the mou...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/66A61K8/67A61K8/92A61Q11/00A61P1/02A61P31/04
Inventor 张宇左思敏朱玲娇李垚曾龙虎
Owner HUBEI SHENDI AGRI SCI & TECH CO LTD
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