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Method and device for quickly detecting hemoglobin

A hemoglobin and fast technology, applied in the field of medical inspection, can solve the problems of user confusion, complexity, and troublesome operation, and achieve the effect of eliminating the scattering effect

Inactive Publication Date: 2015-09-23
马国鹭 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the quantitative measurement method based on dry chemistry has achieved great success, but due to the hygroscopicity of the dry reagent, the storage and use of the dry test piece is also limited by temperature and humidity. In addition, due to the need for hemolysis and chemical Response, operation is more troublesome
[0005] US Patent 6262798 discloses a method that can directly measure the hemoglobin concentration of undiluted and unhemolyzed blood samples. This method uses multiple wavelengths for measurement to eliminate the influence of scattering on the measurement results. Due to the heterogeneity of red blood cells in the blood and the existence of various types Hemoglobin, the system is more complex and only used on large instruments
Cannot be used on a large scale
[0006] In addition, because it takes a certain amount of time for the uniform distribution of red blood cells during measurement, it takes a certain amount of time for the uniform distribution of hemoglobin. Correspondingly, the current existing technology requires a relatively long measurement time and cannot achieve fast measurement, causing great trouble to the user

Method used

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  • Method and device for quickly detecting hemoglobin
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  • Method and device for quickly detecting hemoglobin

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] A method for quickly measuring hemoglobin, its algorithm is:

[0073] tHB=k*(A1-A2)+F(A1-A2)+G(T);

[0074] in, F ( A 1 - A 2 ) = n + m * K = n + m * Δ ( A 1 - A 2 ) Δt ;

[0075] G(T) is a temperature compensation function proposed to compensate for the influence of temperature changes on the detection results.

[0076] Where: tHB is the concentration of hemoglobin;

[0077] A1 is the absorbance of the main measurement wavelength absorption measurement, the logarithm of the ratio of the blank light intensity and the absorption light intensity ...

Embodiment 2

[0092] The present invention also discloses a device for quickly measuring hemoglobin, which can realize the method in Example 1, and the device includes: a light emitting diode 1, a collimating lens 2, a filter 3, a micro-optical cuvette 4, a photoelectric Detector 5, power supply, micro control unit (MCU), constant current circuit, temperature sensor, position sensor, buzzer, barcode scanner, the light emitting diode 1, the photodetector 5, the power supply, the The temperature sensor, the position sensor, the buzzer, and the barcode scanner are all electrically connected to the micro-control unit, and the collimating lens is arranged between the light-emitting diode and the micro-optical cuvette .

[0093] The light-emitting diode 1 is used to alternately send out test beams with two pulse frequencies of the main measurement wavelength and the secondary measurement wavelength; the photodetector 5 is used to detect the intensity of the blank light intensity and the intensity...

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Abstract

The invention relates to a method and device for quickly detecting hemoglobin. Detection results can be given in three seconds. According to the device, the influence of uneven distribution of hemoglobin cells in blood samples can be eliminated through optical modulation, meanwhile, the influence of scattering on the detection results can be well eliminated according to a compensation algorithm, and more prominently, quick detection can be achieved only by using two wave lengths.

Description

technical field [0001] The invention belongs to the field of medical testing, and in particular relates to a method and device for rapidly measuring hemoglobin. Background technique [0002] Red blood cells are the main component of human blood, and the main component of red blood cells is hemoglobin, which is the carrier of oxygen transport in the human body. The concentration of hemoglobin directly affects the ability of the human body to transport oxygen, and then affects the normal metabolism of the human body. Generally, the normal value of hemoglobin for adult males is 120-160g / L, and that for adult females is 110-150g / L. If the hemoglobin concentration is too high or too low, it will reflect certain physiological diseases of the human body. If it is too low, it may be anemia, malnutrition, etc. If it is too high, it may be congenital cardiopulmonary disease, certain tumor diseases, etc. Therefore, the detection of hemoglobin is of great significance. [0003] In the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/31
Inventor 马国鹭
Owner 马国鹭
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