Method used for determining water content of capsule shell

Abstract

The invention discloses a method used for determining water content of capsule shell. The method comprises following steps: (1) substances in soft capsules is removed using a suction part so as to obtain soft capsule shell; (2) the soft capsule shell is cut open with a knife, and residue substances on the inner and the outer surfaces of the soft capsule shell are moved with a solvent; (3) precision weighing of a soft capsule shell sample with a certain weight is carried out, the soft capsule shell sample is delivered into a platode weighing bottle which is dried to constant weight, and then the platode weighing bottle together with the sample are dried to constant weight, and drying loss rate, i.e. water content of the soft capsule sample, is calculated according to drying loss and the weight of the soft capsule shell, wherein drying temperature is controlled to be 115 DEG C. According to the method, direct cutting of the soft capsule shell, which may lead to leakage of the substances in the soft capsule and sticking of the substances onto laboratory coat or arms of operators, in the prior art is abundant; the substances in the soft capsules is removed via suction firstly, and then water content of the capsule shell is determined; design is reasonable and artful, and simple and effective; operation is simple; working efficiency can be increased effectively; and rapid determination of water content of the capsule shell can be realized.

Description

technical field [0001] The invention relates to a method for measuring moisture in capsule rubber, belonging to the field of food and drug processing and testing. Background technique [0002] The capsule is the outer layer of the soft capsule. The raw material composition, water content, and preparation process of the rubber have a great influence on the properties of the rubber, such as plasticity, elasticity, wall thickness, disintegration time limit, and viscosity (too viscous will cause the capsules to stick to each other). influences. The main characteristics of rubber are strong plasticity and high elasticity, and its elasticity is related to the weight ratio of gelatin, plasticizer and water. Depending on the type of gelatin used, the amount of water also affects the properties of the rubber to varying degrees. Therefore, it is extremely important and significant to accurately measure the moisture content in the soft capsule rubber. [0003] In the prior art, some...

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Problems solved by technology

[0003] In the prior art, some enterprises directly use moisture meter and other devices to measure the moisture content of the rubber. However, although the moisture meter is accurate in measurement and the time is short, the required temperature is high, and the purchase of equipment is expensive. high cost

[0004] In addition, the general operation of the existing laboratory is to take a certain amount of soft capsules and cut the capsule rubber. However, when the capsule rubber is cut, the contents (usually oily liquid) in the capsule will easily flow and stick to the surface. to the operator's lab coat or arm, thereby causing unnecessary trouble to the operator and affecting work efficiency