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Compound traditional Chinese medicine for young animals, method for manufacturing compound traditional Chinese medicine and application thereof

A young animal and drug technology, applied in the direction of medical preparations containing active ingredients, drug combinations, pharmaceutical formulas, etc., can solve the problems of high cost and rare, and achieve the effect of facilitating absorption

Inactive Publication Date: 2015-09-09
CHENGDU QIANKUN VETERINARY PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] In addition, when treating viral diarrhea in young animals, usually only western medicine (chemical drugs) can be used, the cost is relatively high, and there are few corresponding dosage forms suitable for young animals
Therefore, how to use traditional Chinese herbal medicines with relatively low cost to prepare a drug suitable for young animal viral diarrhea has become an urgent and challenging topic in this field.

Method used

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  • Compound traditional Chinese medicine for young animals, method for manufacturing compound traditional Chinese medicine and application thereof
  • Compound traditional Chinese medicine for young animals, method for manufacturing compound traditional Chinese medicine and application thereof
  • Compound traditional Chinese medicine for young animals, method for manufacturing compound traditional Chinese medicine and application thereof

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Experimental program
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Effect test

Embodiment 1

[0057] The difficulty of traditional Chinese medicine lies in the dosage. The efficacy of traditional Chinese medicine is not the same as the dosage. Different dosages have different effects, and even the direction of action is opposite. In compound Chinese medicine, the ratio of various medicines is different, and the changes in the functions of the prescription are more abundant. For drugs and drugs, the type, dosage and combination of auxiliary materials are important factors of the drug, which are directly related to whether the drug can be obtained and the quality of the obtained drug. For the present invention (hereinafter referred to as "Electrolytic Bacteria Duqing"), the most important indicators of investigation are efficacy, palatability and disintegration speed. In order to prepare the electrolytic bacterium duqing with definite curative effect, good palatability and fast disintegration speed, the drug formula of the present invention is screened.

[0058] (1) Prep...

Embodiment 2

[0064] Take 7kg of guanzhong and 28kg of schisandra, add 105L of water, boil on high heat, decoct on low heat for 1 hour, filter, and take the filtrate; Add 70L of water, boil on high heat, then decoct on low heat for 20min, filter, and take the filtrate; combine the medicinal liquid obtained three times, and concentrate to 12L; add 5kg of sucrose, 0.08kg of potassium chloride, and 0.07kg of sodium glutamate while it is hot, and mix well ; Take 5kg of pomegranate peel, crush it, and pass it through a No. 9 sieve; mix the two to make soft powder; use a swing-type granulator to make 60-mesh fine particles; add 0.1kg of magnesium stearate, mix well, and spheronize on a spheronizer Prepare into round granules; dry at 35°C-70°C; add mannitol 78kg, microcrystalline fiber (MCC) 3.6kg, low-substituted hydroxypropyl cellulose (L-HPC) 1kg, sodium dodecyl sulfate (SDS) 0.02kg, 0.1kg of magnesium stearate, 0.02kg of sodium glycyrrhizinate and 0.01kg of fresh milk essence, mix well, and pr...

Embodiment 3

[0066] Take Guanzhong 14kg, Schisandra chinensis 21kg, add 105L water, boil on high heat, decoct on low heat for 1 hour, filter, and take the filtrate; add 90L water to the medicinal residue, boil on high heat, decoct on low heat for 40min, filter, and take the filtrate; Add 70L of water, boil on high heat, decoct on low heat for 20min, filter, and take the filtrate; combine the medicinal liquid obtained three times, and concentrate to 12L; add 10 kg of sucrose, 0.1kg of potassium chloride, and 0.2kg of sodium glutamate while it is hot Uniformly; take 9kg of pomegranate peel, crush it, and pass it through a No. 9 sieve; mix the two to make soft powder; use a swing granulator to make 60-mesh fine particles; add 0.3kg of magnesium stearate, mix well, and put it on a spheronizer Prepare round granules by spheronizing; dry at 35°C to 70°C; add 64kg of mannitol, 7kg of MCC, 2kg of L-HPC, 0.1kg of SDS, 0.2kg of magnesium stearate, 0.05 kg of sodium glycyrrhizinate and 0.05 kg of fres...

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Abstract

The invention provides traditional Chinese medicine for treating young animals suffering from viral diarrhea. The traditional Chinese medicine comprises, by weight, 5-33 parts of cyrtomium rhizome, 2-30 parts of schisandra chinensis, 3-20 parts of pomegranate rind, 38.5-85.13 parts of flavoring agents and 4.87-34.2 parts of disintegrants. The flavoring agents comprise 4-80 parts of mannitol, 5-30 parts of cane sugar, 0.05-3 parts of potassium chloride, 0.05-0.5 part of sodium glutamate, 0.02-0.5 part of trisodium glycyrrhizinate and 0.01-0.5 part of fresh milk essence; the disintegrants comprise 3.5-26 parts of microcrystalline celluloses, 1.25-5 parts of low-substituted hydroxypropyl celluloses, 0.1-2.5 parts of magnesium stearate and 0.02-1 part of sodium dodecyl sulfate. The invention further discloses a method for manufacturing the traditional Chinese medicine. The method includes decocting the cyrtomium rhizome and the schisandra chinensis in water to obtain filter liquid, adding powder of the pomegranate rind into the filter liquid to obtain soft materials, adding the magnesium stearate into the soft materials, uniformly mixing the magnesium stearate and soft materials with one another to obtain mixtures, granulating the mixtures to obtain grains and drying the grains; adding the mannitol, the microcrystalline celluloses, the low-substituted hydroxypropyl celluloses, the sodium dodecyl sulfate, the magnesium stearate, the trisodium glycyrrhizinate and the fresh milk essence into the grains and uniformly mixing the mannitol, the microcrystalline celluloses, the low-substituted hydroxypropyl celluloses, the sodium dodecyl sulfate, the magnesium stearate, the trisodium glycyrrhizinate and the fresh milk essence with the grains. The invention further discloses application of the traditional Chinese medicine to treating the young animals suffering from viral diarrhea. The traditional Chinese medicine, the method and the application have the advantages of zero irritability and excellent curative effect.

Description

technical field [0001] The invention belongs to the field of treating young animals' diarrhea, and in particular relates to a compound traditional Chinese medicine for young animals and its preparation method and application; more specifically, it relates to a traditional Chinese medicine for treating young animals' viral diarrhea, its preparation method and its application. Background technique [0002] Young animal diarrhea, especially early viral diarrhea such as infectious gastroenteritis, has the characteristics of difficult prevention, acute onset, and short course of disease. It is a technical problem that has plagued livestock breeding for a long time, especially in recent years, no matter the incidence rate or the mortality rate after the onset of viral diarrhea in young animals is increasing year by year. Therefore, the effective treatment of this disease has very important practical significance to livestock breeding. At present, the prevention and control of vir...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/79A61K36/57A61K47/38A61K47/10A61K47/20A61P1/12A61P31/14
Inventor 丁晓刚房春林唐华侨
Owner CHENGDU QIANKUN VETERINARY PHARMA
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