Anthraquinone compound and preparation method thereof

Abstract

The invention discloses a hedyotis caudatifolia anthraquinone compound and a preparation method thereof. The structural formula of the compound is shown in the specification. The preparation method of the compound comprises the following steps: (1) lixiviating hedyotis caudatifolia in a solvent, performing decompression concentration on the extract, and recovering the solvent until no alcohol taste exists; (2) adding water into the extract to dilute, then extracting with solvents petroleum ether, chloroform, ethyl acetate and n-butyl alcohol with polarities from small to big in sequence to obtain corresponding extracts respectively, performing decompression concentration on the extracts respectively, and collecting dry extract on chloroform part; (3) performing separation and purification on the obtained dry extract on the chloroform part by using column chromatography to obtain the hedyotis caudatifolia anthraquinone compound. The anthraquinone compound is a compound which is discovered for the first time, the types of existing compounds are enriched, the compound has good pharmacological physiological activity, has anti-tumor, hemostasis, antibacterial, purgation and diuretic effects, and is extremely suitable in the medicine absorption aspect, and the development and the utilization of the hedyotis caudatifolia are further promoted.

Description

Technical field [0001] The invention belongs to the field of pharmaceutical compound preparation, and particularly relates to an anthraquinone compound of Eriocheir sinensis and a preparation method thereof. Background technique [0002] Hedyotis caudatifolia Merr.et Metcalf, is the whole plant of Hedyotis caudatifolia Merr.et Metcalf. It is also known as juvenile red, long tail ear grass, thousand-year tea, postpartum tea, and tuberculosis grass. It is a kind of Guangxi Folk medicinal herbs have the effects of relieving cough, resolving phlegm, invigorating the spleen and reducing accumulation. They are often used to treat bronchial asthma, bronchitis, tuberculosis, hemoptysis, malnutrition in children, bruises, swelling and pain, traumatic bleeding, etc. [0003] At present, the researches involved in the research on the roots, stems and leaves of S. auricula mainly include the study of the microstructure of the roots, stems and leaves, the GC-MS analysis of volatile oil componen...

AI Technical Summary

Problems solved by technology

Compared with its widespread use in the folk, there are very few researches on the genus genus at home and abroad at present. The research on the chemical components of genus is almost blank except for the volatile oil components, especially there are many gaps in the research on its active ingredients. This status quo has greatly affected the rational promotion and use of P. saponifera. Therefore, it is extremely important to carry out systematic research on the active ingredients of P. raptoria. It can not only provide a material basis for clarifying the mechanism of action of P. Rational development and utilization of Auricularia fragrans resources, at the same time, provides a material basis for promoting the standardization and internationalization of Aurantium aurantium as a traditional Chinese medicine, and is of great significance for improving the relevant theories of Auricularia aeruginosa and promoting the modernization of traditional Chinese medicine

Images