A process device of Ganoderma lucidum polysaccharide tripeptide separation and filtration system

Abstract

The invention discloses a ganoderan tripeptide filtering system process device. The ganoderan tripeptide filtering system process device is composed of a transporting pump, a stock solution tank, a stop valve, a control valve, a high-pressure pump, a pressure generator, a four-way diverter valve, a series tube, a second four-way diverter valve, a shunt tube, an ultrahigh pressure reaction tank, a polysaccharide peptide storage, a degradation reactor, a refluxing separator, a vacuum pump, a beta-reactor, a protein separator, an ion separator, an ion pump, a homogeneous purifier, a draft tube and a return tube. The ganoderan tripeptide filtering system process device is characterized in that the high-pressure pump and the pressure generator are connected with one end of the refluxing separator through a return tube screw and the other end of the refluxing separator is connected with the screw double-head connector of the high pressure reaction tank through a draft tube screw; a higher pressure than that of the supercritical fluid extracting method is adopted, an ultrahigh pressure is adopted to substitute the supercritical fluid needed temperature cooperation and the damage of the partial substances under high temperature can be avoided; the device is a pure physical extracting process device, the temperature is not higher than 20 DEG C when the ultrahigh pressure is 600 MPa, the low temperature process purifying degree is higher than that of the supercritical fluid extracting method, and the device is an innovative process device for producing the ganoderan peptide injection.

Description

technical field [0001] The invention relates to the synchronous integration of filtration, separation, extraction and purification, and specifically relates to a ganoderma polysaccharide tripeptide separation and filtration system process and device, belonging to the field of bioengineering applications. Background technique [0002] Ganoderma lucidum polysaccharide has the ability to resist oxygen free radicals, can inhibit the generation of O2- free radicals, has a scavenging effect on OH-, can significantly inhibit the peroxidation of red blood cell lipids, has SOD enzyme-like activity, and can scavenge superoxide free radicals. Protecting cells from damage by superoxide free radicals is one of its main functions. The process of submerged fermentation of ganoderma lucidum glycopeptides is complex and the yield is low, especially the removal of protein during the sugar preparation process is currently a difficult point in the separation and purification of polysaccharides ...

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Problems solved by technology

[0002] Ganoderma lucidum polysaccharide has the ability to resist oxygen free radicals, can inhibit the generation of O2- free radicals, has a scavenging effect on OH-, can significantly inhibit the peroxidation of red blood cell lipids, has SOD enzyme-like activity, and can scavenge superoxide free radicals. Protecting cells from damage by superoxide free radicals is one of its main functions. The process of submerged fermentation of ganoderma lucidum glycopeptides is complex and the yield is low, especially the removal of protein during the sugar preparation process is currently a difficult point in the separation and purification of polysaccharides , the Sevag method needs to consume a large amount of organic solvents, and the operation is cumbersome; the boiling point of trifluorotrichloroethane is low (bp56 °C) and is volatile, so it should not be used in large quantities; although trichloroacetic acid can cause the degradation of polysaccharides, it affects its physiological activity. Enzymes are expensive and not suitable for industrial production, but the use of polysaccharide tripeptide separation and filtration system technology and equipment is a purely physical method to remove proteins. Using natural clarifiers for liquid broken Ganoderma lucidum spores can simplify the extraction process and improve the purity of polysaccharides. Decolorization is also a difficult problem in the process of polysaccharide extraction and purification. Activated carbon will absorb polysaccharides and cause loss of polysaccharides; H2O2 oxidative decolorization can easily cause some polysaccharides to degrade

[0003] With the rapid development of my country's economy, the continuous improvement of people's living standards and changes in dietary structure and lifestyle, the incidence of diseases caused by lifestyle such as (diabetes, cardiovascular disease, obesity, colon cancer, constipation, etc.) is increasing year by year High trend, the current treatment effect of diabetes and its complications is still not ideal, so the development of drugs and health food of Ganoderma lucidum polysaccharide peptide is one of the important measures to prevent and improve diabetes and delay the occurrence of complications, and its production process conditions must be improved

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