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Anti-hypertensive preparation

A technology for high blood pressure and compound preparations, applied in the field of medicine, can solve the problems of increased side effects, inaccurate clinical drug dosage, influence on drug efficacy, etc., and achieve the effects of neutralizing adverse reactions, improving antihypertensive efficacy, and reducing adverse reactions.

Inactive Publication Date: 2015-07-08
JIANGSU JIBEIER PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0016] The product of the present invention overcomes the fact that when amlodipine and irbesartan are used clinically, the dosage of the drug is increased to ensure the curative effect when the drug is used alone, resulting in a significant increase in side effects; , and the use of inaccurate clinical dosages affects the defects of drug efficacy

Method used

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Examples

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Embodiment 1

[0036] A compound preparation containing the following components:

[0037]

[0038] This embodiment can be made into compound amlodipine-irbesartan tablets, and the preparation method can adopt the preparation method of common pharmaceutical preparations.

Embodiment 2

[0040] A compound preparation containing the following components:

[0041]

[0042] This embodiment can be made into compound amlodipine-irbesartan tablets, and the preparation method can adopt the preparation method of common pharmaceutical preparations.

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PUM

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Abstract

The invention discloses a compound preparation used for treating hypertension, and particularly relates to an anti-hypertensive preparation. The anti-hypertensive preparation comprises 0.5-5 mg of amlodipine and 5-100 mg of irbesartan. In order to solve the problem that at present, when either amlodipine or irbesartan is clinically used, the drug dose is increased to guarantee the curative effect, and accordingly, side effects are remarkably increased, the invention provides a novel compound preparation in which amlodipine and irbesartan are used together to take a collaborative and complementary curative effect. Therefore, the tolerance of a patient is increased, the compliance is improved, the dosage is reduced to further reduce adverse reaction, and the anti-hypertensive preparation is convenient to take and low in price.

Description

technical field [0001] The invention relates to the technical field of medicine and discloses an antihypertensive preparation. Background technique [0002] Hypertension is the most common cardiovascular disease and a major public health problem worldwide. my country currently has about 100 million hypertensive patients. According to the epidemiological survey in 1991, the awareness rate of hypertension in my country's urban and rural areas was 36% and 13%, and the treatment rate was 17% and 5%, respectively. The form of hypertension prevention and treatment is quite severe. According to the forecast of WTO, by 2020, non-communicable diseases will account for 79% of the causes of death in my country, among which cardiovascular diseases will take the first place. [0003] Commonly used drugs for the treatment of hypertension include the calcium antagonist amlodipine and the angiotensin receptor antagonist irbesartan. [0004] Amlodipine (Amlodipine), the chemical name is 3...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4422A61P9/12A61K31/4184
Inventor 聂丽云魏福荣陈进高瑞银郦红岩
Owner JIANGSU JIBEIER PHARMA
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