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Traditional Chinese medicine prescription for treating rheumatic bone disease and preparation method of Chinese patent medicine

A technology for rheumatic bone disease and traditional Chinese medicine, applied in the field of traditional Chinese medicine and traditional Chinese medicine, can solve problems such as drug toxic and side effects, and achieve the effects of reducing toxic and side effects, good curative effect, and preventing and treating adjuvant arthritis, dispelling wind and dampness

Inactive Publication Date: 2018-05-01
EAST CHINA UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above-mentioned Chinese patent medicines have good curative effect on the treatment of rheumatic arthralgia, because the ingredients of the medicinal materials are complex and contain many non-effective substances, and there are problems of toxic and side effects of the medicines, how to reduce the non-effective ingredients in the Chinese patent medicines and reduce the toxicity? Side effects have always been one of the hot spots in modern Chinese medicine research

Method used

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  • Traditional Chinese medicine prescription for treating rheumatic bone disease and preparation method of Chinese patent medicine
  • Traditional Chinese medicine prescription for treating rheumatic bone disease and preparation method of Chinese patent medicine
  • Traditional Chinese medicine prescription for treating rheumatic bone disease and preparation method of Chinese patent medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] A preparation method of Chinese patent medicine for treating rheumatic bone disease, comprising the following steps:

[0063] (1) Preparation of Glycyrrhizin

[0064] The licorice powder was ultrasonically extracted twice with ammonia ethanol; filtered, concentrated under reduced pressure, and centrifuged; passed through a HZ-816 macroporous resin column, and collected the ethanol eluate; concentrated the eluate to dryness under reduced pressure, dried, weighed, A licorice extract is obtained; the mass percentage of glycyrrhizin in the licorice extract is 50%-95%.

[0065] (2) Preparation of licorice flavonoids

[0066] Glycyrrhizae medicinal materials are taken to be pulverized, extracted with ethanol reflux; centrifuged, concentrated and decolorized; first passed through a D101 macroporous resin column, concentrated and then passed through a HZ915 polyamide resin column; the alcohol solution is concentrated and dried under reduced pressure, and weighed to obtain a li...

Embodiment 2

[0087] A preparation method of Chinese patent medicine for treating rheumatic bone disease, comprising the following steps:

[0088] (1) to (5) Same as Example 1.

[0089] (6) Preparation of effective fraction components

[0090] Prepare the glycyrrhizin, licorice flavonoids, corydalis alkaloids, notoginseng saponins and drynaria flavonoids prepared in steps (1) to (5) according to the following mass parts:

[0091] Glycyrrhizin 8;

[0092] Licorice flavonoids 0.01;

[0093] Corydalis alkaloids 0.01;

[0094] Notoginsenoside 0.01;

[0095] Drynaria flavonoids 0.01.

[0096] (7) Prepare a Chinese patent medicine for treating rheumatic bone disease (same as Example 1).

Embodiment 3

[0098] A preparation method of Chinese patent medicine for treating rheumatic bone disease, comprising the following steps:

[0099] (1) to (5) Same as Example 1.

[0100] (6) Preparation of effective fraction components

[0101] Prepare the glycyrrhizin, licorice flavonoids, corydalis alkaloids, notoginseng saponins and drynaria flavonoids prepared in steps (1) to (5) according to the following mass parts:

[0102] Glycyrrhizin 0.01;

[0103] Licorice flavonoids 2;

[0104] Corydalis alkaloid 5;

[0105] Notoginsenoside 5;

[0106] Drynaria flavonoids 5.

[0107] (7) Prepare a Chinese patent medicine for treating rheumatic bone disease (same as Example 1).

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating rheumatic bone diseases. The traditional Chinese medicine for treating the rheumatic bone diseases comprises the following effective part extracts of liquorice root, yanhusuo, sanchi and fortune's drynaria rhizome: glycyrrhizin, licoflavone, yanhusuo alkaloid, notoginsenoside and fortune's drynaria rhizome flavone, wherein the effective parts are as follows in parts by mass: 0.01-8 parts of glycyrrhizin, 0.01-2 parts of licoflavone, 0.01-5 parts of yanhusuo alkaloid, 0.01-5 parts of notoginsenoside and 0.01-5 parts of fortune's drynaria rhizome flavone. A preparation method of a Chinese patent medicine of the traditional Chinese medicine comprises the following steps: (1), preparing glycyrrhizin; (2), preparing licoflavone; (3), preparing yanhusuo alkaloid; (4), preparing notoginsenoside; (5), preparing fortune's drynaria rhizome flavone; (6), preparing effective part ingredients; and (7), preparing traditional Chinese medicine tables or capsules for treating the rheumatic bone diseases. The traditional Chinese medicine formula for treating the rheumatic bone diseases has the advantages that non-effective ingredients of the Chinese patent medicines can be reduced, toxic and side effects are reduced, the curative effects of dispelling wind and eliminating dampness, promoting qi circulation and relieving pain, and warming and activating meridian are remarkable, and the curative effect for treating the rheumatic bone diseases is excellent.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine and relates to a prescription of traditional Chinese medicine, in particular to a prescription of Chinese medicine for treating rheumatic bone disease and a preparation method thereof (hereinafter referred to as "Chinese patent medicine"). Background technique [0002] Rheumatic arthralgia is a disease caused by the invasion of wind-cold, damp-heat and other exogenous pathogens, resulting in the blockage of meridians and joints and the poor circulation of qi and blood. arthritis". According to the clinical diagnosis, the onset of "rheumatoid arthritis" is mainly due to the relapse of wind, cold and damp pathogens under the premise of weak body, lack of righteousness, loose interstitial tissue, and weak external defense, which makes qi and blood lose circulation. Caused by meridian paralysis. All evils come successively, and each has its own characteristics: if the pain point...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/66A61P29/00A61P19/02A61K31/352
Inventor 倪力军张立国赵雯雯吴婷婷赵丽丽颜玮韬谢婷杨康康王南南程佳佳刘建云
Owner EAST CHINA UNIV OF SCI & TECH
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