A method for preparing silver clusters using hydrogen as a reducing agent

Abstract

The invention provides a silver nanocluster preparation method with hydrogen serving as a reducing agent. The silver nanocluster preparation method is characterized in that polyelectrolyte and silver salt react at a room temperature in a hydrogen atmosphere by taking the polyelectrolyte as a template and the hydrogen as the reducing agent so as to obtain a near-infrared emission silver nanocluster. The silver nanocluster preparation method has the advantages of low cost, simplicity, mild reacting conditions, no participation of highly-toxic substance and more economy and environmental protection, and the prepared silver nanocluster is excellent in fluorescence characteristic and stability.

Description

technical field [0001] The invention relates to the field of synthesis of noble metal nanometer materials, in particular to a method for preparing silver clusters with light-to-fluorescence emission by using hydrogen as a reducing agent. Background technique [0002] Silver nanoclusters (AgNCs) are fluorescent, water-soluble molecular-level aggregates composed of several to dozens of silver atoms. Its unique quantum size effect makes its optical properties vary with particle size, which makes its fluorescence emission spectrum tunable in the range from visible light to near-infrared light. In addition, AgNCs are characterized by good biocompatibility, strong photostability, strong anti-aggregation ability, large Stokes shift and no flickering on all relevant time scales, which greatly improved their performance as biomarkers, significantly Increased sensitivity of existing analytical methods. Therefore, AgNCs are becoming a new favorite in the field of bioanalysis. At pre...

AI Technical Summary

Problems solved by technology

However, the synthesis of AgNCs is difficult due to the complex and time-consuming preparation methods of templates. In addition, the toxic side effects of templates on organisms also hinder the application of AgNCs in the biological field.

Recently, proteins and nucleic acids have been used as templates for the preparation of AgNCs and exhibit good biocompatibility, but their high cost limits the widespread application of AgNCs

At the same time, most of the reducing agents used in the template method are NaBH, which has toxic side effects on the human body. 4 , how to remove its residue is also a big difficulty

[0005] However, the monolayer protection method and ligand etching method are newly emerging preparation methods in the field of AgNCs preparation. The research on their synthesis and application is still in its infancy, and the detailed preparation mechanism is not completely clear, so it cannot be widely used in biological detection and medical diagnosis

[0006] In summary, the current preparation method of AgNCs is to use NaBH in the presence of complex templates. 4 or more complex photochemical reducing agents, which mainly have two problems: 1) template problem: using polyaniline (PANI), polyethanolamine (PEI), polyglycerol-b-polyacrylic acid, etc. The process is complicated and time-consuming; the use of proteins and nucleic acids as soft templates has disadvantages such as high cost

2) The use of reducing agent: most of the reducing agent used in the preparation of AgNCs is NaBH 4 , the reducing agent has disadvantages such as poor stability and complicated operation process

These disadvantages hinder the application of AgNCs

Images