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Compound medicine for ulcerative colitis enema treatment and preparation method and application thereof

A technology for ulcerative colitis and drugs, applied in drug delivery, drug combination, medical preparations containing active ingredients, etc., can solve the problems that cannot be popularized and used, and achieve the effect of accelerating mucosal repair, repairing intestinal mucosa, and easy operation

Active Publication Date: 2015-06-10
HEFEI LIFEON PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is a lack of compound drugs with the best drug ratio in clinical practice, and they cannot be popularized and used

Method used

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  • Compound medicine for ulcerative colitis enema treatment and preparation method and application thereof
  • Compound medicine for ulcerative colitis enema treatment and preparation method and application thereof
  • Compound medicine for ulcerative colitis enema treatment and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A compound medicine for enema treatment of ulcerative colitis, comprising the following components in parts by weight: 30 parts of Cortex Phellodendri, 20 parts of Burnet, 10 parts of Baiji, 3 parts of Panax notoginseng powder, 15 parts of Zicao, 15 parts of Zizhu Ye 10 parts, 10 parts of ebony, 10 parts of schisandra.

[0025] Preparation method: Mix Phellodendron Phellodendron, Burnet, Baiji, Panax notoginseng powder, comfrey, purple pearl leaves, black plum and Schisandra chinensis in the formula amount, add 10 times the weight of water and decoct twice, 1 hour each time, and combine the decoction liquid Filtrate is obtained by filtration, concentrated under reduced pressure to an appropriate amount, centrifuged at a speed of 10,000 to 20,000 rpm in a straight-tube high-speed centrifuge, and then concentrated under reduced pressure until each ml is equivalent to 1 gram of decoction pieces, divided into packages, and sterilized by circulating steam for 45 minutes. Ins...

Embodiment 2

[0027] A compound medicine for enema treatment of ulcerative colitis, comprising the following components in parts by weight: 15 parts of Cortex Phellodendri, 15 parts of Burnet, 6 parts of Baiji, 1 part of Panax notoginseng powder, 5 parts of Zicao, and 5 parts of Zizhu Ye 6 parts, 6 parts of black plum, 6 parts of schisandra.

[0028] Preparation method: mix Phellodendron Phellodendron, Burnet, Baiji, Panax notoginseng powder, comfrey, purple bead leaf, black plum and Schisandra chinensis in the formula amount, add 20 times the weight of water to decoct for 3 hours, filter the decoction to obtain the filtrate, and decompress Concentrate to an appropriate amount, centrifuge at a speed of 10,000 to 20,000 rpm in a straight-tube high-speed centrifuge, continue to concentrate under reduced pressure until each ml is equivalent to 1 gram of decoction pieces, pack in separate packages, and sterilize with circulating steam for 45 minutes to obtain the enema solution.

Embodiment 3

[0030] A compound medicine for enema treatment of ulcerative colitis, comprising the following components in parts by weight: 40 parts of Cortex Phellodendri, 30 parts of Burnet, 20 parts of Baiji, 6 parts of Panax notoginseng powder, 20 parts of Comfrey, and 20 parts of Zizhu Ye 20 parts, 20 parts of ebony, 20 parts of schisandra.

[0031] Preparation method: mix Phellodendron Phellodendron, Burnet, Baiji, Panax notoginseng powder, comfrey, purple bead leaf, black plum and Schisandra chinensis in the formula amount, add 5 times the weight of water to decoct 4 times, each time for 1 hour, and combine the decoction liquid Filtrate is obtained by filtration, concentrated under reduced pressure to an appropriate amount, centrifuged at a speed of 10,000 to 20,000 rpm in a straight-tube high-speed centrifuge, and then concentrated under reduced pressure until each ml is equivalent to 1 gram of decoction pieces, divided into packages, and sterilized by circulating steam for 45 minute...

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Abstract

The invention discloses compound medicine for ulcerative colitis enema treatment. The compound medicine comprises, by weight, 15-40 parts of amur cork tree bark, 15-30 parts of garden burnet roots, 6-20 parts of rhizoma bletillae , 1-6 parts of notoginseng powder, 5-20 parts of Lithospermum erythrorhizon, 5-20 parts of folium callicarpae pedunculatae, 6-20 parts of dark plum fruits and 6-20 parts of fructus schizandrae. The invention further discloses a preparation method and application of the compound medicine. According to the preparation method, an 'internal ulcer' theory is put forward, treatment for ulcerative colitis based on external treatment of Chinese traditional medicine is innovated, systematic representation is performed in pathogenesis, treatment method, prescription and the like, and therefore a theoretical guidance effect on treatment for ulcerative colitis is achieved; the effective compound medicine is provided for the refractory disease of clinical treatment for ulcerative colitis and is economical and practical, thereby having broad clinical application prospects; the preparation method of the enema liquid is simple, quick, efficient and easy to operate, and the compound medicine is convenient to take.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a compound medicine for enema treatment of ulcerative colitis, a preparation method and application thereof. Background technique [0002] Ulcerative colitis (Ulcerative colitis, UC) is a chronic non-specific inflammation that mainly involves the rectum and colonic mucosa. The course of the disease is characterized by chronic, protracted, and recurrent attacks. Under the microscope, it manifests as hyperemia, swelling, and erosion of the mucosa, forming characteristic crypt abscesses. From the perspective of sores and ulcers, the disease should be classified as "internal carbuncle", "internal ulcer" and "yin ulcer". sores" etc. "Surgical Play" believes that: "ulcers are those who have pus out of sores", and modern medicine believes that the surface of ulcers with pus is ulcers. The existence of "rot" is an important reason why sores are difficu...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K9/00A61P1/04
Inventor 沈洪叶柏刘志辉朱磊郑凯
Owner HEFEI LIFEON PHARMA
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