Oil-in-water type menthol ointment and preparation method thereof
An oil-in-water type, peppermint ointment technology is applied in the directions of ointment delivery, pharmaceutical formulations, medical preparations with inactive ingredients, etc. Children use and other problems to achieve the effect of inhibiting the production of inflammatory mediators, promoting epithelial growth, and inhibiting lipoxygenase and cyclooxygenase
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Embodiment 1
[0034] Example 1: Preparation of the oil-in-water peppermint cream of the present invention
[0035] According to the formula shown in Table 1 below, weigh each component separately.
[0036] Table 1
[0037] Ingredients
Dosage
Glycerin
20g
1.5g
1.5g
Eucalyptus blue oil
1.0g
Ammonium Glycyrrhizinate
0.6g
Vitamin E
1.2g
0.3g
0.8g
grape seed oil
4.5g
1.2g
Cetearyl alcohol
5.5g
Caprylic / Capric Triglyceride
4.0g
3.5g
2.0g
0.3g
0.3g
0.008g
0.04g
[0038] Laureth-20
2.0g
Ammonium polyacrylate / C13-16 isoparaffin / Laureth-25
4.0g
Add water to 100g
[0039] Take ammonium glycyrrhizinate, add an appropriate amount of glycerin, stir and suspend it evenly, then add the same amount of purified water as the glycerin, stir and heat to 55°C to dissolve to obtain a lic...
Embodiment 2
[0044] Example 2: Performance test of the oil-in-water peppermint cream of the present invention
[0045] 1. Stability test
[0046] 1. 160℃ high temperature influencing factors test
[0047] Test method: Put the oil-in-water peppermint ointment prepared in Example 1 in a 60°C thermostat, and investigate its pH value, uniformity, discoloration and whether there is water separation at 60°C for 3 days, 7 days, and 14 days , Oil separation, stratification phenomenon, and compared with the sample at room temperature 0 days.
[0048] Test result: The oil-in-water peppermint cream of the present invention has no water, oil, or delamination phenomena under the condition of 60°C for 14 days, and has good uniformity. Compared with the samples at room temperature for 0 days, the pH value and discoloration are no Obvious difference.
[0049] The test results show that the oil-in-water peppermint ointment of the present invention can withstand a certain high temperature and has good stability.
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