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Pharmaceutical composition for treating rheumatoid arthritis, preparation method and patch thereof

A technology for rheumatoid and arthritis, applied in the direction of drug combination, anti-inflammatory agent, pharmaceutical formula, etc., it can solve the problems of airtightness of heating patch, ineffective effect, low-temperature burns, etc., achieve good therapeutic effect, obvious effect, heat Deep and long-lasting effect

Inactive Publication Date: 2015-04-29
SHENZHEN INST OF ADVANCED TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, it has been reported to use patches to treat rheumatoid arthritis. The traditional self-heating patches have the following problems in the process of use: (1) The heating patches generally adopt traditional techniques and simple skin penetration and absorption principles. Most of the heating patches are airtight, which can easily cause low-temperature burns and skin allergies; (2) The traditional patches for treating rheumatoid arthritis are mostly pure Chinese medicine preparations, and the drug action is relatively slow and the effect is not obvious

Method used

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  • Pharmaceutical composition for treating rheumatoid arthritis, preparation method and patch thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0047] A preparation method of a pharmaceutical composition for treating rheumatoid arthritis, comprising the following steps:

[0048] (1) Preparation of thick ointment: take 12 grams each of Chuanduan and Rehmannia glutinosa, 9 grams each of psoralen, epimedium, cassia twig, red peony root, and white peony root, 6 grams of Zhifu tablets, 10 grams of drynariae, Knee, Anemarrhena 9 grams each, Cangzhu 6 grams, Clematis 12 grams, Fangfeng, Shanjia 6 grams each, Shenjincao 20 grams, Ephedra 3 grams, pine knots 10 grams; take the above ingredients into a container and add water decoction, take the boiling liquid;

[0049] Take 12 grams of roasted tiger bone, put it into a container, add water to boil, and take the cooking liquid;

[0050] Mix the above two decoctions to obtain Bushen Quhan Zhiyu Decoction, which is heated, evaporated and concentrated into a thick paste with a relative density of 1.10 at 60°C for later use;

[0051] (2) 5 grams of soybean isoflavones and 1 gram ...

Embodiment 2

[0053] A preparation method of a pharmaceutical composition for treating rheumatoid arthritis, comprising the following steps:

[0054] (1) Preparation of thick ointment: take 15 grams each of Chuanduan and Rehmannia glutinosa, 12 grams each of psoralen, epimedium, cassia twig, red peony root, and white peony, 12 grams of Zhifu tablets, 10 grams of rhizoma drynariae, Knee, Anemarrhena 9 grams each, Cangzhu 6 grams, Clematis 12 grams, Fangfeng, Shanjia 9 grams each, Shenjincao 30 grams, Ephedra 3 grams, pine knots 15 grams; take the above ingredients into a container and add water decoction, take the boiling liquid;

[0055] Take 12 grams of roasted tiger bone, put it into a container, add water to boil, and take the cooking liquid;

[0056] Mix the above two decoctions to obtain Bushen Quhan Zhiyu Decoction, which is heated, evaporated and concentrated into a thick paste with a relative density of 1.10 at 60°C for later use;

[0057] (2) Add 10 grams of soybean isoflavones a...

Embodiment 3

[0059] A preparation method of a pharmaceutical composition for treating rheumatoid arthritis, comprising the following steps:

[0060] (1) Preparation of thick ointment: take 13 grams each of Chuanduan and Rehmannia glutinosa, 10 grams each of psoralen, epimedium, cassia twig, red peony, and white peony root, 10 grams of Zhifu tablets, 10 grams of Drynaria rhizome, Duhuo, tablets Turmeric, Notopterygium, Anemarrhena 9 grams each, Cangzhu 6 grams, Clematis 12 grams, Fangfeng, Shanjia 8 grams each, Shenjincao 25 ​​grams, Ephedra 3 grams, pine knots 12 grams; take the above ingredients into a container Add water to boil and take the cooking liquid;

[0061] Take 20 grams of bone grass, 15 grams of xungufeng, 9 grams of natural copper (quenched with vinegar, first fried) into a container, add water to boil, and take the cooking liquid;

[0062] Mix the above two decoctions to obtain Bushen Quhan Zhiyu Decoction, which is heated, evaporated and concentrated into a thick paste wit...

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Abstract

The invention provides a pharmaceutical composition for treating rheumatoid arthritis, a preparation method and a patch thereof. The pharmaceutical composition for treating rheumatoid arthritis comprises the following components in parts by weight: 50-100 parts of thick paste prepared by evaporating and concentrating decoction for tonifying kidney, dispelling cold and treating bent back bone, 5-10 parts of soy isoflavonoids, and 1-5 parts of diclofenac sodium; and the soy isoflavonoids and the diclofenac sodium are dispersed into the thick paste. The pharmaceutical composition for treating rheumatoid arthritis integrates traditional Chinese medicine and western medicine and acts appropriately to the situation, so that the curative effect is more remarkable. The invention further provides a preparation method of the pharmaceutical composition for treating rheumatoid arthritis, and the preparation method is simple. The invention further provides a patch, the patch comprises a heat conduction layer and a medicine storage layer, wherein the heat conduction layer can avoid low temperature scalding of the self-heating patch and is uniform in through heating and is durable in longitudinal length, the medicine storage layer comprises the pharmaceutical composition for treating rheumatoid arthritis, and the curative effect is good.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a patch thereof, in particular to a pharmaceutical composition for treating rheumatoid arthritis, a preparation method and a patch thereof. Background technique [0002] Rheumatoid arthritis is a chronic, inflammatory synovitis-based systemic disease of unknown etiology. The pathology of rheumatoid arthritis mainly includes the proliferation of synovial lining cells, the infiltration of a large number of inflammatory cells in the interstitium, the neogenesis of microvessels, the formation of pannus, and the destruction of cartilage and bone tissue. [0003] At present, it has been reported to use patches to treat rheumatoid arthritis. The traditional self-heating patches have the following problems in the process of use: (1) The heating patches generally adopt traditional techniques and simple skin penetration and absorption principles. Most of the heating patches are airtight, which can easily...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61K36/9066A61K36/8994A61K36/9064A61K36/8998A61K9/70A61P29/00A61P19/02A61K35/36A61K35/32A61K33/26A61K31/352A61K31/196
Inventor 张鹏汪洁李金超岳野成文翔虎义平马应亚
Owner SHENZHEN INST OF ADVANCED TECH
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