Intermediate-infrared hollow optical fiber ATR coupling probe

Abstract

The invention discloses an intermediate-infrared hollow optical fiber ATR coupling probe and belongs to the technical fields of biomedical photonics and molecular spectrometric measurement and devices. The intermediate-infrared hollow optical fiber ATR coupling probe comprises an ATR crystal probe (1), an incident optical fiber (2-1), an emergent optical fiber (2-2), a handle cover (3), a dual-optical-fiber protective layer (4), a single-optical-fiber protective layer (6), a connecting sleeve (5), an incident optical fiber jumper (7-1) and an emergent optical fiber jumper (7-2). With the adoption of a method for coupling an intermediate-infrared hollow optical fiber and a ZnSe crystal probe, the probe is flexible and convenient due to reasonable design, small-area single-point detection and in-situ measurement can be realized, spectral deformation caused by factors such as light scattering is avoided, the infrared spectroscopy quality is improved, the probe is suitable for in-vivo detection or living body detection and has wide application prospects in the field of biomedicines, and the application range of the ATR spectral measurement technology in the field of biomedical engineering is widened.

Description

technical field [0001] The invention belongs to an infrared spectrum measurement method and a special device for detecting biological tissues in vivo and flexibly monitoring chemical reactions, and belongs to the technical fields of biomedical photonics, molecular spectrum measurement and devices. Background technique [0002] Attenuated total reflection (attenuated total reflection) technology is a new and widely used infrared spectral measurement technology in spectral testing. Attenuated total reflection technology has the advantages of simple sample preparation and cleaning, no need for pretreatment, no damage to the sample, can measure a small amount of water and small particle samples, can eliminate the influence of light scattering and other factors, the measured infrared spectrum is of high quality, and there is no interference fringe. The characteristic bands are clear and not deformed. With the development and wide application of Fourier transform infrared spectro...

AI Technical Summary

Problems solved by technology

Existing ATR measurement accessories lack flexible light import and export components, and the (silver halide) polycrystalline optical fiber and vulcanized glass optical fiber commonly used in the mid-infrared range have certain measurement defects: the vulcanized glass optical fiber has a narrow transmission range for the mid-infrared spectrum And contains toxicity; silver halide polycrystalline fiber has poor chemical stability due to the photosensitive properties of the material

Moreover, the geometric size of the ATR crystal probe is large, and it is difficult to meet the requirements of live detection or even online and real-time measurement we require. In the current biomedical field, infrared waveguide sensor technology is used to perform online and real-time detection by inserting biopsy needles or catheters. The concept and technology of combining visual information and infrared spectral data for minimally invasive medicine (endoscopy) and open surgery to obtain richer tissue information are just two very attractive concepts in the 21st century. Concept and surgical technique (a high luminous flux infrared ATR probe, CN 104062009A; a method and device for detecting the infrared spectrum of biological tissue, CN 1397794A; U Bindig, G Muller, Fiber-optic laser-assisted infrared tumor diagnostics (FLAIR) .J Phys D: Appl Phys 2005; 38, 2716–2731)

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