Method for breeding experimental macaca mulatta

Abstract

The invention provides a method for breeding experimental macaca mulatta. The mode of female money single-cage raising and regular mating is adopted in the mating period, the mode that infant monkeys and a female monkey are raised in a concentrated mode in the lactation period and an adult male monkey is isolated is adopted, the monkey group fighting problem is effectively solved, the infant monkeys are raised in a single-breeding monkey cage in the ablactation period, the breeding quality is further improved, and the health condition of the macaca mulatta can be discovered and managed in time. The breeding rate and the pregnancy rate of the macaca mulatta are further improved, the phenomenon that the female monkey of the right age is infertile in the breeding period is greatly reduced, the oestrus, mating and farrowing activities of personal macaca mulatta can be observed conveniently, and the health condition of the macaca mulatta can be discovered and managed in time. According to the method, overall comprehensive breeding management is combined with rich and reasonable breeding equipment, and thus the yield and the quality of the experimental macaca mulatta are greatly improved.

Description

technical field [0001] The invention relates to the technical field of animal breeding, in particular to a breeding method for experimental rhesus monkeys. Background technique [0002] The macaque (Macaca mulatta) belongs to the genus Macaca (Macaca) in the family Eereopithecidae of the order Primates, and is an appendix II species of the Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES). [0003] Macaque is the species closest to human beings. Nonhuman primates (Nonhuman Primates, NHP) have more than 95% homology with human genetic material, and are similar to human beings in terms of tissue structure, immunity, physiology and metabolism. It is highly similar, so it has obvious comparative advantages in biomedical research, and has become an ideal animal model for basic research and preclinical research to solve human health and disease problems. China SFDA and US FDA clearly require that new drugs of Class II or above must obtain rel...

AI Technical Summary

Problems solved by technology

[0012] 1. The breeding house required for one male and multiple female group breeding requires a large area and high cost;

[0013] 2. One-male-multi-female group breeding is often carried out in an open environment, and the individual contact of macaque populations is frequent, which is not conducive to the control of pathogenic microorganisms;

[0014] 3. The group breeding of one male and multiple females is often mixed, which is not conducive to the observation and recording of individual activities of macaques, and is not convenient for the development of projects such as research on the ecology and behavior of macaques;

[0015] 4. One male multi-female group breeding is often due to the large number of female monkeys that macaque males can choose, but due to the different compatibility between male and female macaques, some female monkeys may be infertile