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Traditional Chinese medicine composition used for treating melanin tumor and preparation method of traditional Chinese medicine composition

A technology of melanoma and composition, which is applied in the direction of drug combination, antineoplastic drugs, and pharmaceutical formulations. It can solve the controversial issues of preventive lymphadenectomy, achieve better drug treatment effects, reduce adverse reactions and side effects, and improve life. quality effect

Inactive Publication Date: 2015-04-08
李绵利
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Involved lymph nodes should be resected, but prophylactic lymphadenectomy remains controversial

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1 Chinese medicine composition of the present invention and preparation technology

[0020] The prescription composition is as follows: Acanthopanax 80g, Codonopsis 50g, Hawthorn 50g, Burnet 30g, Agrimony 100g, Epimedium 50g, Coptis 100g, Chinese Scutellaria baicalensis 30g, Akebia 100g, Phellodendron 80g, Polygonum multiflorum 50g, Lycium barbarum 100g, Mother 30g, turmeric 50g, Gorgon 30g, Dendrobium 30g, Achyranthes bidentata 50g, Galla gall 100g, Angelica 100g, Magnolia officinalis 30g, Astragalus 50g, Honeysuckle 50g, Gastrodia elata 50g, Poria cocos 100g;

[0021] Preparation method: take the prescribed amount of Chinese medicinal materials and crush them into coarse powder, add 40% ethanol solution with a volume concentration of 4 times the total weight of the coarse powder, reflux extraction three times, reflux time is 5h, filter, and recover ethanol after the filtrates are combined, and cool Filter, wash with water, and dry to obtain the Chinese medi...

Embodiment 2

[0022] Embodiment 2 Chinese medicine composition of the present invention and preparation technology

[0023] The composition of the prescription is as follows: Acanthopanax 200g, Codonopsis 150g, Hawthorn 150g, Burnet 100g, Agrimony 250g, Epimedium 150g, Coptis 200g, Scutellaria sinensis 100g, Akebia 200g, Phellodendron 200g, Polygonum multiflorum 120g, Lycium barbarum 200g, 100g turmeric, 150g turmeric, 100g Gorgon, 100g dendrobium, 120g Achyranthes bidentata, 150g gallnut, 200g angelica, 100g magnolia officinalis, 150g astragalus, 150g honeysuckle, 250g gastrodia elata, 200g poria cocos;

[0024] Preparation method: Take the prescribed amount of Chinese medicinal materials and crush them into coarse powder, add 90% ethanol solution according to the volume concentration of 5 times the total weight of the coarse powder, reflux extraction three times, the reflux time is 3h, filter, recycle the ethanol after the filtrates are combined, and cool Filter, wash with water, and dry ...

Embodiment 3

[0025] Embodiment 3 Chinese medicine composition of the present invention and preparation technology

[0026] The composition of the prescription is as follows: Acanthopanax 150g, Codonopsis 100g, Hawthorn 100g, Burnet 70g, Agrimony 180g, Epimedium 100g, Coptis 150g, Scutellaria baicalensis 70g, Akebia 150g, Phellodendron 140g, Polygonum multiflorum 90g, Lycium barbarum 150g, Mother 70g, Turmeric 100g, Gorgon 70g, Dendrobium 60g, Achyranthes bidentata 80g, Galla gall 130g, Angelica 150g, Magnolia officinalis 70g, Astragalus 100g, Honeysuckle 100g, Gastrodia elata 200g, Poria cocos 150g;

[0027] Preparation method: Take the prescription amount of Chinese medicinal materials and crush them into coarse powder, add 70% ethanol solution according to the volume concentration of 5 times the total weight of the coarse powder, reflux extraction three times, reflux time is 4h, filter, recover ethanol after the filtrates are combined, and cool Filter, wash with water, and dry to obtain ...

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Abstract

The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition used for treating a melanin tumor and a preparation method of the traditional Chinese medicine composition. In order to overcome the defect that in the prior art, the side effects on a patient suffering from the melanin tumor in the chemical treatment process are large, the traditional Chinese medicine composition which can treat the melanin tumor is mainly composed of multiple types of traditional Chinese medicine including acanthopanax, radix codonopsis, hawthorn, garden burnet and the like. The cell proliferation of the melanin tumor can be effectively restrained and the cell apoptosis can be obviously induced when the traditional Chinese medicine composition is use for treating the melanin tumor, the side effects of the traditional Chinese medicine composition are small, and the traditional Chinese medicine composition is suitable for being developed into melanin tumor treatment medicine.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating melanoma and a preparation method thereof. Background technique [0002] Malignant melanoma is a tumor that arises from melanocytes in the skin and other organs. Cutaneous melanoma presents as pigmented lesions that change markedly over months or years. Although its incidence rate is low, its malignancy is high, its metastasis occurs early, and its mortality rate is high. Therefore, early diagnosis and early treatment are very important. Malignant melanoma mostly occurs in adults, and cases of secondary canceration of giant congenital pigmented nevus are more common in children. The etiology of melanoma has not been fully elucidated. Some research data suggest that its occurrence is related to the following risk factors: genes, environment and gene / environment common factors. Examples include atypic...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P35/00A61K35/64
CPCA61K36/076A61K36/185A61K36/21A61K36/232A61K36/254A61K36/296A61K36/344A61K36/355A61K36/481A61K36/539A61K36/575A61K36/62A61K36/704A61K36/718A61K36/73A61K36/734A61K36/739A61K36/756A61K36/815A61K36/8964A61K36/8984A61K36/8988A61K36/9066A61K2236/333A61K2236/39A61K2300/00
Inventor 胡学荣
Owner 李绵利
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