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Traditional Chinese medicine compound preparation for treating leucoderma and preparation method of traditional Chinese medicine compound preparation

A compound preparation and vitiligo technology, which is applied in the direction of medical formula, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems affecting the appearance, and achieve the effect of easy operation, convenient carrying, and dust reduction

Inactive Publication Date: 2015-04-01
CENT HOSPITAL XUHUI DISTRICT SHANGHAI CITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Vitiligo not only affects the appearance, but also brings great mental pressure to patients

Method used

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  • Traditional Chinese medicine compound preparation for treating leucoderma and preparation method of traditional Chinese medicine compound preparation
  • Traditional Chinese medicine compound preparation for treating leucoderma and preparation method of traditional Chinese medicine compound preparation
  • Traditional Chinese medicine compound preparation for treating leucoderma and preparation method of traditional Chinese medicine compound preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Embodiment 1, Chinese medicine compound preparation of the present invention-Baweibubai granule

[0041] Chinese medicine raw material formula:

[0042]

[0043] Extraction: in 1M 3Add the above-mentioned Chinese medicine decoction pieces into the multi-functional extraction tank, add purified water to decoct twice, add about 100L of water for the first time and boil for 3 hours, and filter to obtain the filtrate, add 92L of water for the second extraction, boil for 1.5 hours, release the decoction each time liquid, spare;

[0044] Concentration and drying: Combine and release the decoction, filter (200 mesh), concentrate, the maximum steam pressure is 0.2±0.1.3Mpa; or vacuum vacuum concentration, the vacuum degree is (-0.4±0.2Mpa), the maximum steam pressure is 0.2±0.2Mpa 0.1Mpa, concentrated to a liquid relative density of 1.12±0.02 (measured at 60-90°C), YC-015 spray dryer spray drying experimental operating data: working parameter setting, the specific paramete...

Embodiment 2

[0047] Embodiment 2, Chinese medicine compound preparation of the present invention-Baweibubai capsule

[0048] Chinese medicine raw material formula:

[0049]

[0050] Extraction: in 1M 3 Add the above-mentioned raw material decoction pieces of Chinese medicine in the multi-functional extraction tank, add 70% ethanol extraction (1M 3 Multifunctional extraction tank) for the second time, add 320L of solvent (70% ethanol) for the first time, add 280L of water for the second time, heat, reflux and combine the extract, each time for 2 hours, filter, collect the filtrate, and set aside;

[0051] Concentration and drying: recover ethanol from the filtrate, concentrate to a thick paste with a relative density of 1.22±0.02 (60°C), add 10% starch, and dry under reduced pressure (vacuum degree -0.1Mpa, temperature 60±2°C, DZF-6210D vacuum reduction Press drying box), get dry dry extract powder 7.2kg, pulverize, pass 60 orders, for subsequent use;

[0052] Granulation: Add 240g of...

Embodiment 3

[0054] Embodiment 3, Chinese medicine compound preparation of the present invention-Baweibubai pill

[0055] Chinese medicine raw material formula:

[0056]

[0057] Mix the above decoction pieces, use a universal pulverizer (model GF300AZX) to pulverize into a powder of more than 80 mesh, then use a Bailey pulverizer to pulverize into a fine powder of more than 120 mesh, and set aside;

[0058] Granulation: Add 30g of low-substituted hydroxypropyl cellulose to the superfine powder, mix evenly (HD-300 multi-sport mixer), and make pellets with water (LSH-200 wet mixing granulator). II hot air circulation oven) 60 ± 2 ℃ drying, until the moisture content of the pellets is 8%, and set aside;

[0059] Packing: Polish the above-mentioned small pills, pick them, pack 150 pills in each bottle, seal it, and get it.

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Abstract

The invention provides a traditional Chinese medicine compound preparation for treating leucoderma.The preparation comprises the following traditional Chinese medicine raw materials as active ingredients in parts by weight: 10-15 parts of Chinese angelica, 15-20 parts of astragalus mongholicus, 5-10 parts of ligusticum wallichii, 5-10 parts of carthamus tinctorius, 10-15 parts of salt-processed fructus psoraleae, 10-15 parts of prepared rhizoma cyperi, 10-15 parts of fried caltrop and 10-15 parts of salvia miltiorrhiza. The traditional Chinese medicine raw materials are processed traditional Chinese medicine powder or traditional Chinese medicine extracts, and the traditional Chinese medicine compound preparation is a powdered preparation, powder, a pill, a pellet, ointment, a granule and the like. The invention provides a preparation method. The traditional Chinese medicine compound preparation has an exact curative effect and no obvious adverse effects. The preparation is convenient to use and carry and has good clinical application prospects. The preparation method is easy and simple to implement and suitable for industrial production, and has a higher application value, and the raw materials are easy to obtain.

Description

technical field [0001] The invention relates to the preparation of traditional Chinese medicines, in particular to a compound Chinese medicine preparation and a preparation method thereof, in particular to a compound Chinese medicine preparation for treating vitiligo (bawei filling white preparation of traditional Chinese medicine) and a preparation method thereof. Background technique [0002] Vitiligo is an acquired hypopigmentation skin disease, manifested as localized or generalized depigmentation, and is a common, frequently-occurring, and difficult disease in dermatology. Because of its long course of disease, poor treatment effect and high incidence, it is called the king of skin diseases. According to statistics, the disease occurs all over the world, and the incidence rate in the world is 0.5% to 4%. The incidence of vitiligo in China has been on the rise in recent years, and the incidence rate is about 1%. Vitiligo not only affects the appearance, but also brings ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61K47/38A61P17/00
CPCA61K36/232A61K9/1652A61K9/2054A61K9/2059A61K9/282A61K9/4858A61K36/236A61K36/28A61K36/286A61K36/481A61K36/487A61K36/537A61K36/8905A61K2236/33A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 杨莉娅朱建民毛士龙王拂尘张蓉蓉汪硕闻邵宝平李倩
Owner CENT HOSPITAL XUHUI DISTRICT SHANGHAI CITY
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