Method for synthesizing p-chlorobenzaldehyde from p-chlorotoluene

Abstract

The invention discloses a method for synthesizing p-chlorobenzaldehyde from p-chlorotoluene. The method comprises the steps of reacting the p-chlorotoluene with chlorine for 3-8 hours at 160-180 DEG C in the presence of an initiator to generate p-chlorobenzyl chloride, and then performing catalytic hydrolysis for 6-12 hour to obtain p-chlorobenzaldehyde. The method for synthesizing p-chlorobenzaldehyde from p-chlorotoluene is cheap in raw material and simple and convenient in operation.

Description

technical field [0001] The invention belongs to the technical field of organic synthesis, in particular to a method for synthesizing p-chlorobenzaldehyde from p-chlorotoluene. [0002] Background technique [0003] p-Chlorobenzaldehyde is an important intermediate of new pesticides, medicines and dyes. In medicine, p-chlorobenzaldehyde can be condensed and cyclized with mercaptopropionic acid to prepare fenalu. In terms of pesticides, p-chlorobenzaldehyde is used to synthesize the herbicide Maidi San, the plant growth regulator paclobutrazol and uniconazole, etc. In terms of dyes, p-chlorobenzaldehyde is used to synthesize acid blue 7BF, acid brilliant blue 6B, etc. [0004] The country that produces p-chlorobenzaldehyde abroad is mainly the United States, which is at the leading level in process technology development and has realized industrial production. Although the research and development of p-chlorobenzaldehyde started late in my country, it has developed rapidly...

AI Technical Summary

Problems solved by technology

At present, the total domestic production is less than 1000t / a, which is far from meeting the domestic market demand of more than 2500t / a