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Traditional Chinese medicine granule for treating hypertension

A technique for hypertension and granules, applied in the field of preparation of traditional Chinese medicine granules for the treatment of hypertension and traditional Chinese medicine granules for the treatment of diabetic hypertension, can solve the problems of inapplicability to diabetic hypertension, aspirin not suitable for taking at the same time, harm to diabetic patients, and the like, To achieve the effect of improving diabetes, increasing drug efficacy, lowering blood pressure and diabetes

Inactive Publication Date: 2015-02-18
吴翠霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Combined with modern pharmaceutical technology, traditional Chinese medicine granules are easy to store and carry, and the method of administration is simple. It is a commonly used traditional Chinese medicine form. However, the common excipient fillers used in the preparation of granules are starch, lactose, powdered sugar, sucrose and calcium sulfate. Diabetic hypertensive patients take granules containing the first four excipients for a long time, which is equivalent to drinking sugar water for a long time, which may cause harm to diabetic patients; and calcium sulfate and aspirin, a commonly used drug for diabetes, may be incompatible and should not be taken at the same time. Therefore, the traditional Chinese medicine granules are not suitable for diabetic hypertension

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1 prepares the Chinese medicinal granule for the treatment of hypertension

[0020] The formula is: 3 grams of salvia miltiorrhiza, 5 grams of angelica, 8 grams of uncaria, 8 grams of cassia, 8 grams of Eucommia, 8 grams of mulberry, 13 grams of chrysanthemum, 13 grams of Prunella vulgaris, 13 grams of Gastrodia elata, 13 grams of wolfberry, raw licorice 3 grams, 3 grams of crab shell, 2 grams of Tribulus terrestris, 2 grams of silkworm, 12 grams of cassia seed, 60 grams of kudzu root.

[0021] The preparation method is:

[0022] Step 1: After the crab shells are yellowed, grind them into powder to obtain crab shell powder;

[0023] Step 2: Pueraria puerariae is pulverized with a traditional Chinese medicine pulverizer, and 100 mesh sieves are used to obtain Pueraria puerariae powder;

[0024] Step 3: Salvia miltiorrhiza, angelica, uncaria, raw stone cassia, eucommia, mulberry, chrysanthemum, prunella, gastrodia elata, wolfberry, raw licorice, white tribulu...

Embodiment 2

[0027] Embodiment 2 prepares the Chinese medicinal granule for the treatment of hypertension

[0028] The formula is: 8 grams of salvia miltiorrhiza, 10 grams of angelica, 12 grams of uncaria, 12 grams of raw stone cassia, 12 parts of Eucommia, 12 grams of mulberry, 18 grams of chrysanthemum, 18 grams of Prunella vulgaris, 18 grams of Gastrodia elata, 18 grams of wolfberry, raw licorice 8 grams, 8 grams of crab shell, 5 grams of Tribulus terrestris, 5 grams of silkworm, 17 grams of cassia seed, and 90 grams of kudzu root.

[0029]The configuration method is similar to that in Example 1, the difference is that in step 3, add water with a weight multiple of 10 times, decoct twice, decoct for 45 minutes each time, filter after decocting; merge the filtrate twice, concentrate to The relative density is 1.10 (60°C), to obtain a concentrated solution, add ethanol to make the mass fraction of ethanol reach 65%, stir well, let stand for 24 hours, filter and recover ethanol, concentrat...

Embodiment 3

[0031] Embodiment 3 prepares the Chinese medicinal granule for the treatment of hypertension

[0032] The formula is: 5 grams of salvia miltiorrhiza, 6 grams of angelica, 10 grams of uncaria, 10 grams of raw stone cassia, 10 grams of Eucommia, 10 grams of mulberry, 15 grams of chrysanthemum, 15 grams of Prunella vulgaris, 15 grams of Gastrodia elata, 15 grams of wolfberry, raw licorice 6 grams, 6 grams of crab shell, 3 grams of Tribulus terrestris, 3 grams of silkworm, 15 grams of cassia seed, and 80 grams of kudzu root.

[0033] The configuration method is similar to that in Example 1, the difference is that in step 3, add water with a weight multiple of 8 times, decoct twice, decoct for 50 minutes each time, filter after decocting; merge the filtrate twice, concentrate to The relative density is 1.13 (60°C), to obtain a concentrated solution, add ethanol to make the mass fraction of ethanol reach 65%, stir well, let stand for 36 hours, filter and recover ethanol, concentrate...

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Abstract

The invention discloses a traditional Chinese medicine granule for treating hypertension. An effective component of the granule is prepared from the following raw materials: radix salviae miltiorrhizae, angelica sinensis, uncaria rhynchophylla, raw concha haliotidis, eucommia ulmoides, loranthus parasiticus, chrysanthemum, selfheal, rhizoma gastrodiae, lycium barbarum, raw liquorice, crab shell, tribulus terrestris, silkworm larva, semen cassiae and radix puerariae. By adopting a pure traditional Chinese medicine preparation, the granule prevents side effects of Western medicines, has a remarkable and stable blood pressure reduction effect, can comprehensively regulate the human body and also plays a certain curative effect on diabetes; during a preparation process, total powder of the radix puerariae is used as an auxiliary material filling agent to replace a conventional filling agent, so that the granule is safer to take by diabetics and especially applicable to diabetic hypertension patients, so the granule is an ideal pharmaceutic preparation for treating diabetic hypertension.

Description

technical field [0001] The invention relates to a traditional Chinese medicine granule for treating hypertension, in particular to a preparation method of the traditional Chinese medicine granule for treating diabetic hypertension and belongs to the technical field of traditional Chinese medicine preparations. Background technique [0002] Hypertension is a common chronic cardiovascular disease in modern society. Once it develops, it will cause long-term pain and torture to patients, affect the normal life of patients to varying degrees, and even threaten people's lives. There are no obvious symptoms in the early stage of the onset of hypertension, which are easy to be ignored. As the course of the disease continues, patients will often experience symptoms such as headache, dizziness, chest tightness, and palpitations. In severe cases, confusion and convulsions will occur. In view of the various factors that induce hypertension, modern medical research cannot fully explain i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61P9/12A61K35/64A61K35/618A61K35/612
CPCA61K36/8988A61K9/16A61K35/612A61K35/618A61K35/63A61K36/185A61K36/232A61K36/28A61K36/287A61K36/46A61K36/482A61K36/484A61K36/488A61K36/536A61K36/537A61K36/74A61K36/815A61K2236/39A61K2236/53A61K2236/15A61K2236/331A61K2300/00
Inventor 吴翠霞
Owner 吴翠霞
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