Pharmaceutical composition for postoperation radiotherapy after early-stage breast cancer breast conserving surgery

A technology of breast-conserving surgery and composition, which is applied in the direction of drug combination, drug delivery, anti-tumor drugs, etc., can solve problems such as conflict, lack, and influence on curative effect, and achieve the goal of reducing gastrointestinal reactions, nausea, and metabolic burden Effect

Inactive Publication Date: 2015-01-28
迟玉华
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in prescriptions, the two drugs are used together, and their effects conflict, affecting the curative effect.
[0005] Therefore, there is still a lack of a traditional Chinese medicine or formula that does not simply start from the perspective of "killing" or "strengthening", and is used in conjunction with radiotherapy and chemotherapy for synergistic use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1, the weight ratio of raw materials: 20g of Rhizoma chinensis, 20g of Mujianghua, 6g of Ye Chuxiao, 6g of Polygonum multiflorum, 10g of red clover, 10g of Senecio, 3g of acacia, 2g of cassia twig.

[0020] The preparation method of Example 1 is as follows: mix and decoct wild prawns, wood ginger flowers, night flute, Polygonum multiflorum, red clover, Senecio, acacia, and cassia twigs, take the filtrate after 30 minutes, add water to the medicinal residues and continue to decoct After boiling for 20 minutes, take the filtrate, combine the two filtrates, divide into two parts and take it in the morning and evening.

Embodiment 2

[0021] Example 2, the weight ratio of raw materials: 10 parts of Rhizoma chinensis, 10 parts of Mujianghua, 3 parts of Ye Chuxiao, 3 parts of Polygonum multiflorum, 6 parts of red clover, 6 parts of Senecio, 1 part of acacia, 1 part of cassia twig 10 parts of peach gum, 3 parts of pine needles, 50 parts of flax oil.

Embodiment 3

[0022] Example 3, the weight ratio of raw materials: 20 parts of Rhizoma chinensis, 20 parts of Mujianghua, 6 parts of Ye Chuan Xiao, 6 parts of Polygonum multiflorum, 10 parts of red clover, 10 parts of Senecio, 3 parts of acacia, 2 parts of cassia twig 20 parts of peach gum, 9 parts of pine needles, 50 parts of flax oil.

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PUM

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Abstract

The invention discloses a pharmaceutical composition for postoperation radiotherapy after early-stage breast cancer breast conserving surgery, and solves the problem of postoperation radiotherapy after breast cancer surgery. The pharmaceutical composition is characterized by being prepared through the following raw materials according to weight ratio: elsholtzia rugulosa, tomentosecalyx elsholtzia leaf, leycesteria formosa, polygonum multiflorum, red clover, groundsel, Chinese honey locust and cassia twig. Clinical experiments prove that the pharmaceutical composition has a radiotherapy synergia effect, has the characteristics of good curative effect and high safety, and is worth of clinical application and promotion.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for radiotherapy after breast conserving surgery for early breast cancer. Background technique [0002] The incidence of malignant tumors has been increasing in recent years. Chemotherapy, surgery, and radiotherapy are the main means of cancer treatment. Maximum tolerated dose chemotherapy (maximum tolerated dose, MTD) is the main form of traditional chemotherapy. Due to its heavy side effects, each cycle of chemotherapy requires an interval of 2 to 3 weeks to facilitate the recovery of body tissue and organ functions, which is prone to tumor resistance. medicine. At present, there are many theories such as the tumor stem cell hypothesis, which can explain that tumor cells are not sensitive to radiotherapy and chemotherapy or develop drug resistance or resistance during treatment, resulting in tumor recurrence and metastasis. In order to ...

Claims

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Application Information

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IPC IPC(8): A61K36/704A61P35/00
CPCA61K36/53A61K9/08A61K36/28A61K36/355A61K36/48A61K36/483A61K36/54A61K36/704A61K2236/331A61K2236/39A61K2236/53
Inventor 迟玉华
Owner 迟玉华
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