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Synergetic medicinal composition for nasopharynx cancer chemoradiotherapy

A technique for radiotherapy and chemotherapy and nasopharyngeal carcinoma, which is applied in the field of nasopharyngeal carcinoma radiotherapy and chemotherapy-enhancing drug composition, can solve the problems of affecting the curative effect, conflict, deficiency, etc., and achieve the effects of improving tumor inhibition rate, promoting tumor growth and reducing tumor weight.

Inactive Publication Date: 2015-01-21
所俊强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in prescriptions, the two drugs are used together, and their effects conflict, affecting the curative effect.
[0005] Therefore, there is still a lack of a traditional Chinese medicine or formula that does not simply start from the perspective of "killing" or "strengthening", and is used in conjunction with radiotherapy and chemotherapy for synergistic use.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Example 1, the weight ratio of raw materials: 20g of Rhizoma japonica, 20g of Ginger Flower, 6g of Ye Chuxiao, 9g of Pinellia Qu, 6g of Polygonum multiflorum, 10g of Red Trifolium, 10g of Senecio, 3g of Chinese Japonica, 10g of Shichangpu, osmanthus Branch 2g, peach gum 20g.

[0032] The preparation method of Example 1 is: mix and decoct the seeds of wild pluck, wood ginger flower, night blow flute, pinellia song (decoction), fleece-flower root, red clover, Senecio, acacia, calamus and cassia twig, After 30 minutes, take the filtrate, add water to the dregs and continue to decoct for 20 minutes, then take the filtrate. Combine the two filtrates and divide them into two parts. Take half the daily dose of peach gum in the morning and evening, melt and take it.

Embodiment 2

[0033] Example 2, the weight ratio of raw materials: 10 parts of Rhizoma chinensis, 10 parts of Mujianghua, 3 parts of Ye Chuan Xiao, 6 parts of Pinellia Qu, 3 parts of Polygonum multiflorum, 6 parts of red clover, 6 parts of Senecio, and acacia 1 part, 6 parts of Shichangpu, 1 part of Guizhi, 10 parts of peach gum, 3 parts of pine needles, 50 parts of sesame oil.

Embodiment 3

[0034] Example 3, the weight ratio of raw materials: 20 parts of Rhizoma chinensis, 20 parts of Mujianghua, 6 parts of Ye Chuan Xiao, 9 parts of Pinellia Qu, 6 parts of Polygonum multiflorum, 10 parts of red clover, 10 parts of Senecio, acacia 3 parts, 10 parts of Shichangpu, 2 parts of Guizhi, 20 parts of peach gum, 9 parts of pine needles, 50 parts of sesame oil.

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PUM

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Abstract

The invention discloses a synergetic medicinal composition for nasopharynx cancer chemoradiotherapy, and aims to solve the treatment problem of nasopharynx cancer. The synergetic medicinal composition is characterized by comprising the following raw medicinal materials in percentage by weight: elsholtzia rugulosa, pungent litse flower, leycesteria formosa, rhizoma pinelliae, polygonum multiflorum, trifolium pratense, groundsel, Chinese honey locust, acorus gramineus, cassia twig and peach gum. The clinical experiments show that the synergetic medicinal composition is synergetic with the chemotherapy, good in in curative effect, high in safety, and worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a nasopharyngeal carcinoma radiochemotherapy-enhancing pharmaceutical composition. Background technique [0002] The incidence of malignant tumors has been increasing in recent years. Chemotherapy, surgery, and radiotherapy are the main means of cancer treatment. Maximum tolerated dose chemotherapy (maximum tolerated dose, MTD) is the main form of traditional chemotherapy. Due to its heavy side effects, each cycle of chemotherapy requires an interval of 2 to 3 weeks to facilitate the recovery of body tissue and organ functions, which is prone to tumor resistance. medicine. At present, there are many theories such as the tumor stem cell hypothesis, which can explain that tumor cells are not sensitive to radiotherapy and chemotherapy or develop drug resistance or resistance during treatment, resulting in tumor recurrence and metastasis. In order to "completely" kill tu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8888A61P35/00
CPCA61K36/53A61K36/15A61K36/185A61K36/28A61K36/35A61K36/48A61K36/483A61K36/54A61K36/704A61K36/736A61K36/888A61K36/8888
Inventor 曹伟余小妹迟玉华
Owner 所俊强
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