Raw material composition of active wound repair material and preparation method of raw material composition

Abstract

The invention discloses a raw material composition of an active wound repair material and a preparation method of the raw material composition. The raw material composition is prepared from the following components in percentage by weight: 15-51% of an analytically pure reagent anhydrous sodium carbonate, 14-19% of calcium carbonate, 25-57% of silicon dioxide, 6-20% of calcium fluoride, 4-17% of tricalcium phosphate and 2-20% of medical sodium hyaluronate, or 9-51% of an analytically pure reagent anhydrous sodium carbonate, 5-50% of calcium carbonate, 38-58% of silicon dioxide, 5-22% of tricalcium phosphate and 2-20% of medical sodium hyaluronate. The raw material composition can be prepared into external preparations such as gel and ointment for treating the skin wound. The active wound repair material disclosed by the invention can be used for inducing proliferation and differentiation of human epithelial cells, promoting the regeneration of soft tissues, quickening the generation of granulation tissues, promoting the wound to heal and reducing the formation of scars, and therefore has a wide medical application prospect.

Description

technical field [0001] The invention relates to a material for healing wounds, that is, an active wound repair material, which belongs to the technical field of medical hygiene materials and dressings. Background technique [0002] There are many dressings for treating wounds in the prior art, but they need to be improved in the absorption of wound exudate, promoting blood vessel growth, improving microcirculation, promoting wound healing, and reducing scar formation, especially for diabetic ulcers, decubitus ulcers, burns and wounds. Wounds that are difficult to heal caused by unknown reasons have worse treatment effects, bring greater mental and physical pain to patients, and increase the economic burden of patients. [0003] In recent years, a new type of wound repair material has also appeared. Patent 200510104916.2 proposes to use silicon dioxide, sodium oxide, calcium oxide and phosphorus pentoxide to physically mix, crush, sieve (300μm), and then mix it with hyaluron...

AI Technical Summary

Problems solved by technology

[0002] There are many dressings for treating wounds in the prior art, but they need to be improved in the absorption of wound exudate, promoting blood vessel growth, improving microcirculation, promoting wound healing, and reducing scar formation, especially for diabetic ulcers, decubitus ulcers, burns and wounds. Wounds that are difficult to heal caused by unknown reasons, the treatment effect is worse, bring greater mental and physical pain to patients, and increase the economic burden of patients

[0003] In recent years, a new type of wound repair material has also appeared. Patent 200510104916.2 proposes to use silicon dioxide, sodium oxide, calcium oxide and phosphorus pentoxide to physically mix, crush, sieve (300μm), and then mix it with hyaluronic acid. Wound repair material, the patent is a multi-substance mixed powder prepared by physical mixing technology, its crystal structure is still an independent single crystal mixture, and the uniformity, biological activity and therapeutic effect of the tissue need to be improved

Images