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Traditional Chinese medicine for treating cold stasis type vasculitis and preparation method thereof

A technology of vasculitis and traditional Chinese medicine, applied in the field of pharmacy, can solve the problems of large side effects, poor anti-inflammatory effect, and inability to completely cure vasculitis, and achieve the effect of small side effects and definite curative effect

Inactive Publication Date: 2015-01-07
高瑛
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Western medicine mainly treats vasculitis with anti-inflammatory and analgesic medicines. Western medicine can indeed improve the condition, but the anti-inflammatory effect is poor and side effects are large, so it cannot completely cure vasculitis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0041] The present invention also provides the preparation method of above-mentioned Chinese medicine, and the dosage form of described Chinese medicine is tablet, and its preparation method comprises the following steps:

[0042] Step 1: Mix the components of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 85-95% that is 3-5 times the mass of the mixture, heat and reflux for 1-3 hours, extract, and filter to obtain the first extract , filter the dregs obtained, then add ethanol with an alcohol concentration of 85-95% relative to the quality of the dregs 2-4 times, heat and reflux for 1-2 hours, extract, filter to obtain the second extract, mix the first extract and The second extracts were combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0043] The second step: put the dry paste obtained in the first step into a superfine pulverizer for 1 to 2 hours, pulverize and sieve...

Embodiment 1

[0049] Example 1 tablet

[0050] Take 60g of Sandianjincao, 140g of inverted flowers, 120g of reed vine, 80g of Polygonum chinensis, 180g of red bone ginseng, 210g of Dashenjin, 340g of horseradish grass, 160g of double feather grass, 70g of herbal fruit medicine, 170g of spider incense, 140g of Yinxiangpi, 70g of Jianweifeng, 120g of Fenghancao, 240g of Tongjingcao, 60g of white cauliflower and 320g of Surgeon grass;

[0051] Prepare as follows:

[0052] The first step: mix the components of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 95% that is 4 times the mass of the mixture, heat and reflux for 3 hours, extract, filter to obtain the first extract, and filter the obtained medicinal residues Then add ethanol with an alcohol concentration of 95% relative to the quality of the dregs, heat and reflux for 1 hour, extract, filter to obtain the second extract, combine the first extract and the second extract, and concentrate under...

Embodiment 2

[0055] Embodiment 2 Granules

[0056] Take 80g of Sandianjincao, 120g of inverted flowers, 140g of reed vine, 60g of Polygonum japonica, 160g of red bone ginseng, 230g of Dashenjin, 310g of horseradish grass, 180g of double feather grass, 80g of herbal fruit medicine, 160g of spider incense, 120g of Yinxiangpi, 90g of Jianweifeng, 140g of Fenghancao, 220g of Tongjingcao, 80g of white cauliflower and 340g of Surgeon grass;

[0057] Prepare as follows:

[0058] The first step: mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration 3 times that of the mixture and be 85% ethanol, heat to boiling and reflux for 2 hours, filter, and slow down the mixture at a rate of 2ml per minute by percolation method. Slow percolation, collect the percolation liquid, then concentrate under reduced pressure at 0.05Mpa to a paste with a relative density of 1.02 at 70°C, and spray dry. The air inlet temperature of the spray dryer is 180°C, and the o...

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Abstract

The invention provides traditional Chinese medicine for treating cold stasis type vasculitis and a preparation method thereof. The traditional Chinese medicine comprises the following raw medicinal materials: desmodium triflorum, asarum wulingense, stem of falsenettleleaf pepper, actinidia polygama, root of longcoronate sage, smilax nipponica, horseradish grass, root of shrubby elsholtzia, hedychium spicatum, valeriana jatamansi, burmann cinnamon bark, callicarpa longissima, lysimachia congestiflora, silvery aleuritopteris, spiderflower seed and siberian walking fern. According to the invention, the traditional Chinese medicine has the efficacies of warming channels, dredging collaterals, dispelling cold, removing dampness, promoting blood circulation, relieving pain, dispersing swelling and blood stasis and has the advantages of definite curative effects and small side effects on the treatment of the cold stasis type vasculitis.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for treating cold-stasis type vasculitis and a preparation method thereof. Background technique [0002] Thromboangiitis obliterans is called vasculitis for short. Refers to a chronic persistent and progressive vascular inflammatory lesion of peripheral vessels (medium and small arteries and veins), leading to thrombosis and occlusion of the vessel lumen. The lesions mainly involve the medium and small arteries of the distal extremities, and the accompanying veins and superficial veins are also often involved, mainly the lower extremities. In severe cases, ulcers and gangrene that are not easy to heal may occur on the extremities, which may lead to permanent dysfunction or loss of limbs, or even death. [0003] Western medicine treatment of vasculitis is mainly based on anti-inflammatory and analgesic western medicines. Western medicine can indee...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/906A61P9/14
CPCA61K36/48A61K9/1652A61K9/2059A61K36/11A61K36/185A61K36/53A61K36/54A61K36/57A61K36/67A61K36/83A61K36/85A61K36/906A61K2236/333A61K2236/39
Inventor 高瑛卢秀霞
Owner 高瑛
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